Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth

Toni T. Lemmetyinen; Emma W. Viitala; Linnea Wartiovaara; Tuomas Kaprio; Jaana Hagström; Caj Haglund; Pekka Katajisto; Timothy C. Wang; Eva Domenech-Moreno; Saara Ollila

doi:10.1242/dmm.049692

Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth

Toni T. Lemmetyinen
, Emma W. Viitala
, Linnea Wartiovaara
, Tuomas Kaprio
, Jaana Hagström
, Caj Haglund
, Pekka Katajisto
, Timothy C. Wang
, Eva Domenech-Moreno
, Saara Ollila

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Disease Models & Mechanisms
Vuosikerta	16
Numero	4
Sivumäärä	18
ISSN	1754-8403
DOI - pysyväislinkit	https://doi.org/10.1242/dmm.049692
Tila	Julkaistu - huhtik. 2023
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

Colorectal cancer
Egf
Ereg
Intestinal regeneration
Nrg1
3111 Biolääketieteet
1182 Biokemia, solu- ja molekyylibiologia

Pääsy asiakirjaan

10.1242/dmm.049692

dmm049692Lopullinen julkaistu versio, 10,4 MBLisenssi: CC BY

Siteeraa tätä

Lemmetyinen, T. T., Viitala, E. W., Wartiovaara, L., Kaprio, T., Hagström, J., Haglund, C., Katajisto, P., Wang, T. C., Domenech-Moreno, E., & Ollila, S. (2023). Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth. Disease Models & Mechanisms, 16(4). https://doi.org/10.1242/dmm.049692

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title = "Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth",

keywords = "Colorectal cancer, Egf, Ereg, Intestinal regeneration, Nrg1, 3111 Biomedicine, 1182 Biochemistry, cell and molecular biology",

author = "Lemmetyinen, \{Toni T.\} and Viitala, \{Emma W.\} and Linnea Wartiovaara and Tuomas Kaprio and Jaana Hagstr{\"o}m and Caj Haglund and Pekka Katajisto and Wang, \{Timothy C.\} and Eva Domenech-Moreno and Saara Ollila",

year = "2023",

month = apr,

doi = "10.1242/dmm.049692",

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Lemmetyinen, TT , Viitala, EW, Wartiovaara, L, Kaprio, T , Hagström, J , Haglund, C , Katajisto, P, Wang, TC, Domenech-Moreno, E & Ollila, S 2023, 'Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth', Disease Models & Mechanisms, Vuosikerta 16, Nro 4. https://doi.org/10.1242/dmm.049692

TY - JOUR

T1 - Fibroblast-derived EGF ligand neuregulin 1 induces fetal-like reprogramming of the intestinal epithelium without supporting tumorigenic growth

AU - Lemmetyinen, Toni T.

AU - Viitala, Emma W.

AU - Wartiovaara, Linnea

AU - Kaprio, Tuomas

AU - Hagström, Jaana

AU - Haglund, Caj

AU - Katajisto, Pekka

AU - Wang, Timothy C.

AU - Domenech-Moreno, Eva

AU - Ollila, Saara

PY - 2023/4

Y1 - 2023/4

KW - Colorectal cancer

KW - Egf

KW - Ereg

KW - Intestinal regeneration

KW - Nrg1

KW - 3111 Biomedicine

KW - 1182 Biochemistry, cell and molecular biology

U2 - 10.1242/dmm.049692

DO - 10.1242/dmm.049692

M3 - Article

C2 - 36912192

SN - 1754-8403

VL - 16

JO - Disease Models & Mechanisms

JF - Disease Models & Mechanisms

IS - 4

ER -