Genetic studies of body mass index yield new insights for obesity biology

Adam E. Locke, Bratati Kahali, Sonja I. Berndt, Anne E. Justice, Tune H. Pers, Felix R. Day, Corey Powell, Sailaja Vedantam, Martin L. Buchkovich, Jian Yang, Damien C. Croteau-Chonka, Tonu Esko, Tove Fall, Teresa Ferreira, Stefan Gustafsson, Zoltan Kutalik, Jian'an Luan, Reedik Maegi, Joshua C. Randall, Thomas W. Winkler & 44 muut Andrew R. Wood, Tsegaselassie Workalemahu, Jessica D. Faul, Jennifer A. Smith, Jing Hua Zhao, Wei Zhao, Jin Chen, Rudolf Fehrmann, Asa K. Hedman, Juha Karjalainen, Ellen M. Schmidt, Devin Absher, Najaf Amin, Denise Anderson, Marian Beekman, Jennifer L. Bolton, L. Bragg-Gresham, Niina Eklund, Markku Koskenvuo, Niina Sandholm, Johan G. Eriksson, Pekka Jousilahti, Jaakko Kaprio, Juha Sinisalo, Leif C. Groop, Mika Kivimaki, Markus Perola, Jaakko Tuomilehto, LifeLines Cohort Study, ADIPOGen Consortium, AGEN-BMI Working Grp, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GLGC, ICBP, MAGIC Investigators, MuTHER Consortium, MIGen Consortium, PAGE Consortium, ReproGen Consortium, GENIE Consortium, Int Endogene Consortium, Marja-Liisa Lokki, Samuli Olli Ripatti

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

Alkuperäiskielienglanti
LehtiNature
Vuosikerta518
Numero7538
Sivut197-U401
Sivumäärä23
ISSN0028-0836
DOI - pysyväislinkit
TilaJulkaistu - 12 helmikuuta 2015
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Lisätietoja

M.-L. Lokki ja S. Ripatti työryhmien jäseniä.
Volume:
Proceeding volume:

Tieteenalat

  • 3121 Sisätaudit
  • 3142 Kansanterveystiede, ympäristö ja työterveys

Lainaa tätä

Locke, A. E., Kahali, B., Berndt, S. I., Justice, A. E., Pers, T. H., Day, F. R., ... Ripatti, S. O. (2015). Genetic studies of body mass index yield new insights for obesity biology. Nature, 518(7538), 197-U401. https://doi.org/10.1038/nature14177
Locke, Adam E. ; Kahali, Bratati ; Berndt, Sonja I. ; Justice, Anne E. ; Pers, Tune H. ; Day, Felix R. ; Powell, Corey ; Vedantam, Sailaja ; Buchkovich, Martin L. ; Yang, Jian ; Croteau-Chonka, Damien C. ; Esko, Tonu ; Fall, Tove ; Ferreira, Teresa ; Gustafsson, Stefan ; Kutalik, Zoltan ; Luan, Jian'an ; Maegi, Reedik ; Randall, Joshua C. ; Winkler, Thomas W. ; Wood, Andrew R. ; Workalemahu, Tsegaselassie ; Faul, Jessica D. ; Smith, Jennifer A. ; Zhao, Jing Hua ; Zhao, Wei ; Chen, Jin ; Fehrmann, Rudolf ; Hedman, Asa K. ; Karjalainen, Juha ; Schmidt, Ellen M. ; Absher, Devin ; Amin, Najaf ; Anderson, Denise ; Beekman, Marian ; Bolton, Jennifer L. ; Bragg-Gresham, L. ; Eklund, Niina ; Koskenvuo, Markku ; Sandholm, Niina ; Eriksson, Johan G. ; Jousilahti, Pekka ; Kaprio, Jaakko ; Sinisalo, Juha ; Groop, Leif C. ; Kivimaki, Mika ; Perola, Markus ; Tuomilehto, Jaakko ; LifeLines Cohort Study ; ADIPOGen Consortium ; AGEN-BMI Working Grp ; CARDIOGRAMplusC4D Consortium ; CKDGen Consortium ; GLGC ; ICBP ; MAGIC Investigators ; MuTHER Consortium ; MIGen Consortium ; PAGE Consortium ; ReproGen Consortium ; GENIE Consortium ; Int Endogene Consortium ; Lokki, Marja-Liisa ; Ripatti, Samuli Olli. / Genetic studies of body mass index yield new insights for obesity biology. Julkaisussa: Nature. 2015 ; Vuosikerta 518, Nro 7538. Sivut 197-U401.
@article{379001146280415e997289bc5163b7ae,
title = "Genetic studies of body mass index yield new insights for obesity biology",
keywords = "GENOME-WIDE ASSOCIATION, PROVIDES INSIGHTS, GLYCEMIC TRAITS, HUMAN HEIGHT, LOCI, METAANALYSIS, VARIANTS, EXPRESSION, PATHWAYS, ARCHITECTURE, 3121 Internal medicine, 3142 Public health care science, environmental and occupational health",
author = "Locke, {Adam E.} and Bratati Kahali and Berndt, {Sonja I.} and Justice, {Anne E.} and Pers, {Tune H.} and Day, {Felix R.} and Corey Powell and Sailaja Vedantam and Buchkovich, {Martin L.} and Jian Yang and Croteau-Chonka, {Damien C.} and Tonu Esko and Tove Fall and Teresa Ferreira and Stefan Gustafsson and Zoltan Kutalik and Jian'an Luan and Reedik Maegi and Randall, {Joshua C.} and Winkler, {Thomas W.} and Wood, {Andrew R.} and Tsegaselassie Workalemahu and Faul, {Jessica D.} and Smith, {Jennifer A.} and Zhao, {Jing Hua} and Wei Zhao and Jin Chen and Rudolf Fehrmann and Hedman, {Asa K.} and Juha Karjalainen and Schmidt, {Ellen M.} and Devin Absher and Najaf Amin and Denise Anderson and Marian Beekman and Bolton, {Jennifer L.} and L. Bragg-Gresham and Niina Eklund and Markku Koskenvuo and Niina Sandholm and Eriksson, {Johan G.} and Pekka Jousilahti and Jaakko Kaprio and Juha Sinisalo and Groop, {Leif C.} and Mika Kivimaki and Markus Perola and Jaakko Tuomilehto and {LifeLines Cohort Study} and {ADIPOGen Consortium} and {AGEN-BMI Working Grp} and {CARDIOGRAMplusC4D Consortium} and {CKDGen Consortium} and GLGC and ICBP and {MAGIC Investigators} and {MuTHER Consortium} and {MIGen Consortium} and {PAGE Consortium} and {ReproGen Consortium} and {GENIE Consortium} and {Int Endogene Consortium} and Marja-Liisa Lokki and Ripatti, {Samuli Olli}",
note = "M.-L. Lokki ja S. Ripatti ty{\"o}ryhmien j{\"a}seni{\"a}. Volume: Proceeding volume:",
year = "2015",
month = "2",
day = "12",
doi = "10.1038/nature14177",
language = "English",
volume = "518",
pages = "197--U401",
journal = "Nature",
issn = "0028-0836",
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number = "7538",

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Locke, AE, Kahali, B, Berndt, SI, Justice, AE, Pers, TH, Day, FR, Powell, C, Vedantam, S, Buchkovich, ML, Yang, J, Croteau-Chonka, DC, Esko, T, Fall, T, Ferreira, T, Gustafsson, S, Kutalik, Z, Luan, J, Maegi, R, Randall, JC, Winkler, TW, Wood, AR, Workalemahu, T, Faul, JD, Smith, JA, Zhao, JH, Zhao, W, Chen, J, Fehrmann, R, Hedman, AK, Karjalainen, J, Schmidt, EM, Absher, D, Amin, N, Anderson, D, Beekman, M, Bolton, JL, Bragg-Gresham, L, Eklund, N, Koskenvuo, M, Sandholm, N, Eriksson, JG, Jousilahti, P, Kaprio, J, Sinisalo, J, Groop, LC, Kivimaki, M, Perola, M, Tuomilehto, J, LifeLines Cohort Study, ADIPOGen Consortium, AGEN-BMI Working Grp, CARDIOGRAMplusC4D Consortium, CKDGen Consortium, GLGC, ICBP, MAGIC Investigators, MuTHER Consortium, MIGen Consortium, PAGE Consortium, ReproGen Consortium, GENIE Consortium, Int Endogene Consortium, Lokki, M-L & Ripatti, SO 2015, 'Genetic studies of body mass index yield new insights for obesity biology', Nature, Vuosikerta 518, Nro 7538, Sivut 197-U401. https://doi.org/10.1038/nature14177

Genetic studies of body mass index yield new insights for obesity biology. / Locke, Adam E.; Kahali, Bratati; Berndt, Sonja I.; Justice, Anne E.; Pers, Tune H.; Day, Felix R.; Powell, Corey; Vedantam, Sailaja; Buchkovich, Martin L.; Yang, Jian; Croteau-Chonka, Damien C.; Esko, Tonu; Fall, Tove; Ferreira, Teresa; Gustafsson, Stefan; Kutalik, Zoltan; Luan, Jian'an; Maegi, Reedik; Randall, Joshua C.; Winkler, Thomas W.; Wood, Andrew R.; Workalemahu, Tsegaselassie; Faul, Jessica D.; Smith, Jennifer A.; Zhao, Jing Hua; Zhao, Wei; Chen, Jin; Fehrmann, Rudolf; Hedman, Asa K.; Karjalainen, Juha; Schmidt, Ellen M.; Absher, Devin; Amin, Najaf; Anderson, Denise; Beekman, Marian; Bolton, Jennifer L.; Bragg-Gresham, L.; Eklund, Niina; Koskenvuo, Markku; Sandholm, Niina; Eriksson, Johan G.; Jousilahti, Pekka; Kaprio, Jaakko; Sinisalo, Juha; Groop, Leif C.; Kivimaki, Mika; Perola, Markus; Tuomilehto, Jaakko; LifeLines Cohort Study; ADIPOGen Consortium; AGEN-BMI Working Grp; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; Int Endogene Consortium ; Lokki, Marja-Liisa; Ripatti, Samuli Olli.

julkaisussa: Nature, Vuosikerta 518, Nro 7538, 12.02.2015, s. 197-U401.

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Genetic studies of body mass index yield new insights for obesity biology

AU - Locke, Adam E.

AU - Kahali, Bratati

AU - Berndt, Sonja I.

AU - Justice, Anne E.

AU - Pers, Tune H.

AU - Day, Felix R.

AU - Powell, Corey

AU - Vedantam, Sailaja

AU - Buchkovich, Martin L.

AU - Yang, Jian

AU - Croteau-Chonka, Damien C.

AU - Esko, Tonu

AU - Fall, Tove

AU - Ferreira, Teresa

AU - Gustafsson, Stefan

AU - Kutalik, Zoltan

AU - Luan, Jian'an

AU - Maegi, Reedik

AU - Randall, Joshua C.

AU - Winkler, Thomas W.

AU - Wood, Andrew R.

AU - Workalemahu, Tsegaselassie

AU - Faul, Jessica D.

AU - Smith, Jennifer A.

AU - Zhao, Jing Hua

AU - Zhao, Wei

AU - Chen, Jin

AU - Fehrmann, Rudolf

AU - Hedman, Asa K.

AU - Karjalainen, Juha

AU - Schmidt, Ellen M.

AU - Absher, Devin

AU - Amin, Najaf

AU - Anderson, Denise

AU - Beekman, Marian

AU - Bolton, Jennifer L.

AU - Bragg-Gresham, L.

AU - Eklund, Niina

AU - Koskenvuo, Markku

AU - Sandholm, Niina

AU - Eriksson, Johan G.

AU - Jousilahti, Pekka

AU - Kaprio, Jaakko

AU - Sinisalo, Juha

AU - Groop, Leif C.

AU - Kivimaki, Mika

AU - Perola, Markus

AU - Tuomilehto, Jaakko

AU - LifeLines Cohort Study

AU - ADIPOGen Consortium

AU - AGEN-BMI Working Grp

AU - CARDIOGRAMplusC4D Consortium

AU - CKDGen Consortium

AU - GLGC

AU - ICBP

AU - MAGIC Investigators

AU - MuTHER Consortium

AU - MIGen Consortium

AU - PAGE Consortium

AU - ReproGen Consortium

AU - GENIE Consortium

AU - Int Endogene Consortium

AU - Lokki, Marja-Liisa

AU - Ripatti, Samuli Olli

N1 - M.-L. Lokki ja S. Ripatti työryhmien jäseniä. Volume: Proceeding volume:

PY - 2015/2/12

Y1 - 2015/2/12

KW - GENOME-WIDE ASSOCIATION

KW - PROVIDES INSIGHTS

KW - GLYCEMIC TRAITS

KW - HUMAN HEIGHT

KW - LOCI

KW - METAANALYSIS

KW - VARIANTS

KW - EXPRESSION

KW - PATHWAYS

KW - ARCHITECTURE

KW - 3121 Internal medicine

KW - 3142 Public health care science, environmental and occupational health

U2 - 10.1038/nature14177

DO - 10.1038/nature14177

M3 - Article

VL - 518

SP - 197-U401

JO - Nature

JF - Nature

SN - 0028-0836

IS - 7538

ER -

Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR et al. Genetic studies of body mass index yield new insights for obesity biology. Nature. 2015 helmi 12;518(7538):197-U401. https://doi.org/10.1038/nature14177