Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model

Eva Ramsay; Marika Ruponen; Theo Picardat; Unni Tengvall; Marjo Tuomainen; Seppo Auriola; Elisa Toropainen; Arto Urtti; Eva M. del Amo

doi:10.1016/j.xphs.2017.04.061

Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model

Eva Ramsay, Marika Ruponen, Theo Picardat, Unni Tengvall, Marjo Tuomainen, Seppo Auriola, Elisa Toropainen, Arto Urtti, Eva M. del Amo

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Journal of Pharmaceutical Sciences
Vuosikerta	106
Numero	9
Sivut	2463-2471
Sivumäärä	9
ISSN	0022-3549
DOI - pysyväislinkit	https://doi.org/10.1016/j.xphs.2017.04.061
Tila	Julkaistu - syysk. 2017
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

317 Farmasia
116 Kemia

Pääsy asiakirjaan

10.1016/j.xphs.2017.04.061

Siteeraa tätä

Ramsay, E., Ruponen, M., Picardat, T., Tengvall, U., Tuomainen, M., Auriola, S., Toropainen, E., Urtti, A., & del Amo, E. M. (2017). Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model. Journal of Pharmaceutical Sciences, 106(9), 2463-2471. https://doi.org/10.1016/j.xphs.2017.04.061

@article{479f6b6530b64a169d3a927c4cf71690,

title = "Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model",

keywords = "permeability, ophthalmic drug delivery, QSPR, absorption, principal component analysis, partial least square, PIGMENTED RABBIT CONJUNCTIVA, SYSTEMIC ABSORPTION, EPITHELIAL-CELLS, QUANTITATIVE-EVALUATION, TRANSPORT-PROPERTIES, CORNEAL PENETRATION, P-GLYCOPROTEIN, SURFACE-AREA, DELIVERY, PILOCARPINE, 317 Pharmacy, 116 Chemical sciences",

author = "Eva Ramsay and Marika Ruponen and Theo Picardat and Unni Tengvall and Marjo Tuomainen and Seppo Auriola and Elisa Toropainen and Arto Urtti and {del Amo}, {Eva M.}",

year = "2017",

month = sep,

doi = "10.1016/j.xphs.2017.04.061",

language = "English",

volume = "106",

pages = "2463--2471",

journal = "Journal of Pharmaceutical Sciences",

issn = "0022-3549",

publisher = "Wiley",

number = "9",

}

Ramsay, E, Ruponen, M, Picardat, T, Tengvall, U, Tuomainen, M, Auriola, S, Toropainen, E, Urtti, A & del Amo, EM 2017, 'Impact of Chemical Structure on Conjunctival Drug Permeability: Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model', Journal of Pharmaceutical Sciences, Vuosikerta 106, Nro 9, Sivut 2463-2471. https://doi.org/10.1016/j.xphs.2017.04.061

Impact of Chemical Structure on Conjunctival Drug Permeability : Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model. / Ramsay, Eva; Ruponen, Marika; Picardat, Theo et al.

julkaisussa: Journal of Pharmaceutical Sciences, Vuosikerta 106, Nro 9, 09.2017, s. 2463-2471.

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Impact of Chemical Structure on Conjunctival Drug Permeability

T2 - Adopting Porcine Conjunctiva and Cassette Dosing for Construction of In Silico Model

AU - Ramsay, Eva

AU - Ruponen, Marika

AU - Picardat, Theo

AU - Tengvall, Unni

AU - Tuomainen, Marjo

AU - Auriola, Seppo

AU - Toropainen, Elisa

AU - Urtti, Arto

AU - del Amo, Eva M.

PY - 2017/9

Y1 - 2017/9

KW - permeability

KW - ophthalmic drug delivery

KW - QSPR

KW - absorption

KW - principal component analysis

KW - partial least square

KW - PIGMENTED RABBIT CONJUNCTIVA

KW - SYSTEMIC ABSORPTION

KW - EPITHELIAL-CELLS

KW - QUANTITATIVE-EVALUATION

KW - TRANSPORT-PROPERTIES

KW - CORNEAL PENETRATION

KW - P-GLYCOPROTEIN

KW - SURFACE-AREA

KW - DELIVERY

KW - PILOCARPINE

KW - 317 Pharmacy

KW - 116 Chemical sciences

U2 - 10.1016/j.xphs.2017.04.061

DO - 10.1016/j.xphs.2017.04.061

M3 - Article

VL - 106

SP - 2463

EP - 2471

JO - Journal of Pharmaceutical Sciences

JF - Journal of Pharmaceutical Sciences

SN - 0022-3549

IS - 9

ER -