Incorrect aseptic techniques in medicine preparation and recommendations for safer practices: a systematic review

Tutkimustuotos: ArtikkelijulkaisuKatsausartikkeliTieteellinenvertaisarvioitu

Kuvaus

Objective Many patient deaths have been reported because of administration of contaminated intravenous medicines due to incorrect aseptic techniques. Our aim was to review the literature for (1) incorrect practices in aseptic drug preparation and administration and (2) recommendations for safer practices in hospitals.
Methods A systematic literature search was conducted in PubMed covering 2007–2015. Studies were included if they concerned aseptic medicine preparation and administration in hospitals by different healthcare professionals, assessed incorrect practices and made recommendations for safer aseptic preparation and administration.
Results 26 studies were included of which 19 were original articles. 12 of the studies concerned description of incorrect practices that led to contamination. The studies reported 11 incorrect practices that increased the risk of contamination of parenteral medicines. The most reported incorrect practices were multiple use of phials and syringes (2/12 studies) and lack of overall disinfection during the aseptic preparation and administration (3/12 studies). 22 practices were recommended to avoid contamination, which were classified into six categories: equipment and medicines (7); disinfection (6); working environment (3); storing (3); catheter care (2) and quality of prepared medicines (1). The results indicate that pharmacists prepared syringes with less contamination than nurses because of the pharmacist's aseptic skills and environmental aspects in pharmacy units.
Conclusions The review discusses many appropriate and enhanced practices in aseptic drug preparation and administration. As the change for the better in contamination rates of administered medicines seems to be challenging to achieve in hospitals, better and possibly international procedures for safe parenteral practices need to be developed.
Alkuperäiskielienglanti
LehtiEuropean journal of hospital pharmacy-Science and practice
Vuosikerta24
Sivut175-181
Sivumäärä7
ISSN2047-9956
DOI - pysyväislinkit
TilaJulkaistu - 2017
OKM-julkaisutyyppiA2 Katsausartikkeli tieteellisessä aikakauslehdessä

Tieteenalat

  • 317 Farmasia

Lainaa tätä

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title = "Incorrect aseptic techniques in medicine preparation and recommendations for safer practices: a systematic review",
abstract = "Objective Many patient deaths have been reported because of administration of contaminated intravenous medicines due to incorrect aseptic techniques. Our aim was to review the literature for (1) incorrect practices in aseptic drug preparation and administration and (2) recommendations for safer practices in hospitals.Methods A systematic literature search was conducted in PubMed covering 2007–2015. Studies were included if they concerned aseptic medicine preparation and administration in hospitals by different healthcare professionals, assessed incorrect practices and made recommendations for safer aseptic preparation and administration.Results 26 studies were included of which 19 were original articles. 12 of the studies concerned description of incorrect practices that led to contamination. The studies reported 11 incorrect practices that increased the risk of contamination of parenteral medicines. The most reported incorrect practices were multiple use of phials and syringes (2/12 studies) and lack of overall disinfection during the aseptic preparation and administration (3/12 studies). 22 practices were recommended to avoid contamination, which were classified into six categories: equipment and medicines (7); disinfection (6); working environment (3); storing (3); catheter care (2) and quality of prepared medicines (1). The results indicate that pharmacists prepared syringes with less contamination than nurses because of the pharmacist's aseptic skills and environmental aspects in pharmacy units.Conclusions The review discusses many appropriate and enhanced practices in aseptic drug preparation and administration. As the change for the better in contamination rates of administered medicines seems to be challenging to achieve in hospitals, better and possibly international procedures for safe parenteral practices need to be developed.",
keywords = "317 Pharmacy, PATIENT SAFETY, Quality Assurance, Health Care, Medication safety, medicine compounding, aseptic practice",
author = "Eeva Suvikas-Peltonen and Hakoinen, {Suvi Marjaana} and Ercan Celikkayalar and Laaksonen, {Raisa Aurora} and Airaksinen, {Marja Sisko Anneli}",
year = "2017",
doi = "10.1136/ejhpharm-2016-001015",
language = "English",
volume = "24",
pages = "175--181",
journal = "European journal of hospital pharmacy-Science and practice",
issn = "2047-9956",
publisher = "BMJ PUBLISHING GROUP",

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Incorrect aseptic techniques in medicine preparation and recommendations for safer practices: a systematic review. / Suvikas-Peltonen, Eeva; Hakoinen, Suvi Marjaana; Celikkayalar, Ercan; Laaksonen, Raisa Aurora; Airaksinen, Marja Sisko Anneli.

julkaisussa: European journal of hospital pharmacy-Science and practice, Vuosikerta 24, 2017, s. 175-181.

Tutkimustuotos: ArtikkelijulkaisuKatsausartikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Incorrect aseptic techniques in medicine preparation and recommendations for safer practices: a systematic review

AU - Suvikas-Peltonen, Eeva

AU - Hakoinen, Suvi Marjaana

AU - Celikkayalar, Ercan

AU - Laaksonen, Raisa Aurora

AU - Airaksinen, Marja Sisko Anneli

PY - 2017

Y1 - 2017

N2 - Objective Many patient deaths have been reported because of administration of contaminated intravenous medicines due to incorrect aseptic techniques. Our aim was to review the literature for (1) incorrect practices in aseptic drug preparation and administration and (2) recommendations for safer practices in hospitals.Methods A systematic literature search was conducted in PubMed covering 2007–2015. Studies were included if they concerned aseptic medicine preparation and administration in hospitals by different healthcare professionals, assessed incorrect practices and made recommendations for safer aseptic preparation and administration.Results 26 studies were included of which 19 were original articles. 12 of the studies concerned description of incorrect practices that led to contamination. The studies reported 11 incorrect practices that increased the risk of contamination of parenteral medicines. The most reported incorrect practices were multiple use of phials and syringes (2/12 studies) and lack of overall disinfection during the aseptic preparation and administration (3/12 studies). 22 practices were recommended to avoid contamination, which were classified into six categories: equipment and medicines (7); disinfection (6); working environment (3); storing (3); catheter care (2) and quality of prepared medicines (1). The results indicate that pharmacists prepared syringes with less contamination than nurses because of the pharmacist's aseptic skills and environmental aspects in pharmacy units.Conclusions The review discusses many appropriate and enhanced practices in aseptic drug preparation and administration. As the change for the better in contamination rates of administered medicines seems to be challenging to achieve in hospitals, better and possibly international procedures for safe parenteral practices need to be developed.

AB - Objective Many patient deaths have been reported because of administration of contaminated intravenous medicines due to incorrect aseptic techniques. Our aim was to review the literature for (1) incorrect practices in aseptic drug preparation and administration and (2) recommendations for safer practices in hospitals.Methods A systematic literature search was conducted in PubMed covering 2007–2015. Studies were included if they concerned aseptic medicine preparation and administration in hospitals by different healthcare professionals, assessed incorrect practices and made recommendations for safer aseptic preparation and administration.Results 26 studies were included of which 19 were original articles. 12 of the studies concerned description of incorrect practices that led to contamination. The studies reported 11 incorrect practices that increased the risk of contamination of parenteral medicines. The most reported incorrect practices were multiple use of phials and syringes (2/12 studies) and lack of overall disinfection during the aseptic preparation and administration (3/12 studies). 22 practices were recommended to avoid contamination, which were classified into six categories: equipment and medicines (7); disinfection (6); working environment (3); storing (3); catheter care (2) and quality of prepared medicines (1). The results indicate that pharmacists prepared syringes with less contamination than nurses because of the pharmacist's aseptic skills and environmental aspects in pharmacy units.Conclusions The review discusses many appropriate and enhanced practices in aseptic drug preparation and administration. As the change for the better in contamination rates of administered medicines seems to be challenging to achieve in hospitals, better and possibly international procedures for safe parenteral practices need to be developed.

KW - 317 Pharmacy

KW - PATIENT SAFETY

KW - Quality Assurance, Health Care

KW - Medication safety

KW - medicine compounding

KW - aseptic practice

U2 - 10.1136/ejhpharm-2016-001015

DO - 10.1136/ejhpharm-2016-001015

M3 - Review Article

VL - 24

SP - 175

EP - 181

JO - European journal of hospital pharmacy-Science and practice

JF - European journal of hospital pharmacy-Science and practice

SN - 2047-9956

ER -