Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

Hanna Vauhkonen; Hannimari Kallio-Kokko; Eija Hiltunen-Back; Lasse  Lönnqvist; Jaana Leppäaho-Lakka; Laura Mannonen; Ravi Kant; Tarja Sironen; Satu Kurkela; Maija Lappalainen; Tomaž Mark Zorec; Samo Zakotnik; Doroteja  Vlaj; Miša  Korva; Tatjana  Avšič-Županc; Mario  Poljak; Teemu Smura; Olli Vapalahti

doi:10.3201/eid2903.221388

Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

Hanna Vauhkonen
, Hannimari Kallio-Kokko
, Eija Hiltunen-Back
, Lasse Lönnqvist
, Jaana Leppäaho-Lakka
, Laura Mannonen
, Ravi Kant
, Tarja Sironen
, Satu Kurkela
, Maija Lappalainen
, Tomaž Mark Zorec
, Samo Zakotnik
, Doroteja Vlaj
, Miša Korva
, Tatjana Avšič-Županc
, Mario Poljak
, Teemu Smura
, Olli Vapalahti

Tutkimustuotos: Artikkelijulkaisu › Kirje › Tieteellinen › vertaisarvioitu

Abstrakti

Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.

Alkuperäiskieli	englanti
Lehti	Emerging Infectious Diseases
Vuosikerta	29
Numero	3
Sivut	649-652
Sivumäärä	4
ISSN	1080-6040
DOI - pysyväislinkit	https://doi.org/10.3201/eid2903.221388
Tila	Julkaistu - maalisk. 2023
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

11832 Mikrobiologia ja virologia
3141 Terveystiede

Pääsy asiakirjaan

10.3201/eid2903.221388Lisenssi: CC BY

22-1388Lopullinen julkaistu versio, 1,08 MBLisenssi: CC BY

Siteeraa tätä

Vauhkonen, H., Kallio-Kokko, H., Hiltunen-Back, E., Lönnqvist, L., Leppäaho-Lakka, J., Mannonen, L., Kant, R., Sironen, T., Kurkela, S., Lappalainen, M., Zorec, T. M., Zakotnik, S., Vlaj, D., Korva, M., Avšič-Županc, T., Poljak, M., Smura, T., & Vapalahti, O. (2023). Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022. Emerging Infectious Diseases, 29(3), 649-652. https://doi.org/10.3201/eid2903.221388

@article{cc169f14e58448d48a9dacb1ab91eb7b,

title = "Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022",

abstract = "Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.",

keywords = "11832 Microbiology and virology, 3141 Health care science",

author = "Hanna Vauhkonen and Hannimari Kallio-Kokko and Eija Hiltunen-Back and Lasse L{\"o}nnqvist and Jaana Lepp{\"a}aho-Lakka and Laura Mannonen and Ravi Kant and Tarja Sironen and Satu Kurkela and Maija Lappalainen and Zorec, \{Toma{\v z} Mark\} and Samo Zakotnik and Doroteja Vlaj and Mi{\v s}a Korva and Tatjana Av{\v s}i{\v c}-{\v Z}upanc and Mario Poljak and Teemu Smura and Olli Vapalahti",

year = "2023",

month = mar,

doi = "10.3201/eid2903.221388",

language = "English",

volume = "29",

pages = "649--652",

journal = "Emerging Infectious Diseases",

issn = "1080-6040",

publisher = "Centers for Disease Control and Prevention (CDC)",

number = "3",

}

Vauhkonen, H, Kallio-Kokko, H, Hiltunen-Back, E, Lönnqvist, L, Leppäaho-Lakka, J, Mannonen, L , Kant, R , Sironen, T , Kurkela, S , Lappalainen, M, Zorec, TM, Zakotnik, S, Vlaj, D, Korva, M, Avšič-Županc, T, Poljak, M, Smura, T & Vapalahti, O 2023, 'Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022', Emerging Infectious Diseases, Vuosikerta 29, Nro 3, Sivut 649-652. https://doi.org/10.3201/eid2903.221388

TY - JOUR

T1 - Intrahost Monkeypox Virus Genome Variation in Patient with Early Infection, Finland, 2022

AU - Vauhkonen, Hanna

AU - Kallio-Kokko, Hannimari

AU - Hiltunen-Back, Eija

AU - Lönnqvist, Lasse

AU - Leppäaho-Lakka, Jaana

AU - Mannonen, Laura

AU - Kant, Ravi

AU - Sironen, Tarja

AU - Kurkela, Satu

AU - Lappalainen, Maija

AU - Zorec, Tomaž Mark

AU - Zakotnik, Samo

AU - Vlaj, Doroteja

AU - Korva, Miša

AU - Avšič-Županc, Tatjana

AU - Poljak, Mario

AU - Smura, Teemu

AU - Vapalahti, Olli

PY - 2023/3

Y1 - 2023/3

N2 - Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.

AB - Monkeypox virus was imported into Finland during late May–early June 2022. Intrahost viral genome variation in a sample from 1 patient comprised a major variant with 3 lineage B.1.3–specific mutations and a minor variant with ancestral B.1 nucleotides. Results suggest either ongoing APOBEC3 enzyme–mediated evolution or co-infection.

KW - 11832 Microbiology and virology

KW - 3141 Health care science

U2 - 10.3201/eid2903.221388

DO - 10.3201/eid2903.221388

M3 - Letter

SN - 1080-6040

VL - 29

SP - 649

EP - 652

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 3

ER -