Lymphatic Vessels in Regenerative Medicine and Tissue Engineering

Mira Schaupper, Michael Jeltsch, Sabrina Rohringer, Heinz Redl, Wolfgang Holnthoner

Tutkimustuotos: ArtikkelijulkaisuKatsausartikkeliTieteellinenvertaisarvioitu

Kuvaus

The lymphatic system is involved in maintaining interstitial fluid homeostasis, fat absorption and immune surveillance. Dysfunction of lymphatic fluid uptake can lead to lymphedema. Worldwide up to 250 million people are estimated to suffer from this disfiguring and disabling disease, which places a strain on the healthcare system as well as on the affected patients. The severity of lymphatic diseases calls for the establishment of new treatment methods. One approach is to replace dysfunctional lymphatic vessels with bio-engineered ones. Here, we mainly focus on hydrogels, scaffolds with cellular constructs, interstitial flow, and extracorporeal shock wave therapy. This review provides an overview on the current status of lymphatic biology and approaches of reconstruction and regeneration of lymphatic vascular tissues.
Alkuperäiskielienglanti
LehtiTissue Engineering. Part B. Reviews
Vuosikerta22
Numero5
Sivut395-407
Sivumäärä13
ISSN1937-3368
DOI - pysyväislinkit
TilaJulkaistu - 2016
OKM-julkaisutyyppiA2 Katsausartikkeli tieteellisessä aikakauslehdessä

Lisätietoja

Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/ten.TEB.2016.0034
Volume:
Proceeding volume:

Tieteenalat

  • 3111 Biolääketieteet

Lainaa tätä

Schaupper, Mira ; Jeltsch, Michael ; Rohringer, Sabrina ; Redl, Heinz ; Holnthoner, Wolfgang. / Lymphatic Vessels in Regenerative Medicine and Tissue Engineering. Julkaisussa: Tissue Engineering. Part B. Reviews. 2016 ; Vuosikerta 22, Nro 5. Sivut 395-407.
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abstract = "The lymphatic system is involved in maintaining interstitial fluid homeostasis, fat absorption and immune surveillance. Dysfunction of lymphatic fluid uptake can lead to lymphedema. Worldwide up to 250 million people are estimated to suffer from this disfiguring and disabling disease, which places a strain on the healthcare system as well as on the affected patients. The severity of lymphatic diseases calls for the establishment of new treatment methods. One approach is to replace dysfunctional lymphatic vessels with bio-engineered ones. Here, we mainly focus on hydrogels, scaffolds with cellular constructs, interstitial flow, and extracorporeal shock wave therapy. This review provides an overview on the current status of lymphatic biology and approaches of reconstruction and regeneration of lymphatic vascular tissues.",
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author = "Mira Schaupper and Michael Jeltsch and Sabrina Rohringer and Heinz Redl and Wolfgang Holnthoner",
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Lymphatic Vessels in Regenerative Medicine and Tissue Engineering. / Schaupper, Mira; Jeltsch, Michael; Rohringer, Sabrina; Redl, Heinz; Holnthoner, Wolfgang.

julkaisussa: Tissue Engineering. Part B. Reviews, Vuosikerta 22, Nro 5, 2016, s. 395-407.

Tutkimustuotos: ArtikkelijulkaisuKatsausartikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Lymphatic Vessels in Regenerative Medicine and Tissue Engineering

AU - Schaupper, Mira

AU - Jeltsch, Michael

AU - Rohringer, Sabrina

AU - Redl, Heinz

AU - Holnthoner, Wolfgang

N1 - Final publication is available from Mary Ann Liebert, Inc., publishers http://dx.doi.org/10.1089/ten.TEB.2016.0034 Volume: Proceeding volume:

PY - 2016

Y1 - 2016

N2 - The lymphatic system is involved in maintaining interstitial fluid homeostasis, fat absorption and immune surveillance. Dysfunction of lymphatic fluid uptake can lead to lymphedema. Worldwide up to 250 million people are estimated to suffer from this disfiguring and disabling disease, which places a strain on the healthcare system as well as on the affected patients. The severity of lymphatic diseases calls for the establishment of new treatment methods. One approach is to replace dysfunctional lymphatic vessels with bio-engineered ones. Here, we mainly focus on hydrogels, scaffolds with cellular constructs, interstitial flow, and extracorporeal shock wave therapy. This review provides an overview on the current status of lymphatic biology and approaches of reconstruction and regeneration of lymphatic vascular tissues.

AB - The lymphatic system is involved in maintaining interstitial fluid homeostasis, fat absorption and immune surveillance. Dysfunction of lymphatic fluid uptake can lead to lymphedema. Worldwide up to 250 million people are estimated to suffer from this disfiguring and disabling disease, which places a strain on the healthcare system as well as on the affected patients. The severity of lymphatic diseases calls for the establishment of new treatment methods. One approach is to replace dysfunctional lymphatic vessels with bio-engineered ones. Here, we mainly focus on hydrogels, scaffolds with cellular constructs, interstitial flow, and extracorporeal shock wave therapy. This review provides an overview on the current status of lymphatic biology and approaches of reconstruction and regeneration of lymphatic vascular tissues.

KW - 3111 Biomedicine

U2 - 10.1089/ten.TEB.2016.0034

DO - 10.1089/ten.TEB.2016.0034

M3 - Review Article

VL - 22

SP - 395

EP - 407

JO - Tissue Engineering. Part B. Reviews

JF - Tissue Engineering. Part B. Reviews

SN - 1937-3368

IS - 5

ER -