Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

Olivia Solomon; Karen Huen; Paul Yousefi; Leanne K. Küpers; Juan R. González; Matthew Suderman; Sarah E. Reese; Christian M. Page; Olena Gruzieva; Peter Rzehak; Lu Gao; Kelly M. Bakulski; Alexei Novoloaca; Catherine Allard; Irene Pappa; Maria Llambrich; Marta Vives; Dereje D. Jima; Tuomas Kvist; Andrea Baccarelli; Cory White; Faisal I. Rezwan; Gemma C. Sharp; Gwen Tindula; Anna Bergström; Veit Grote; John F. Dou; Elena Isaevska; Maria C. Magnus; Eva Corpeleijn; Patrice Perron; Vincent W.V. Jaddoe; Ellen A. Nohr; Lea Maitre; Maria Foraster; Cathrine Hoyo; Siri E. Håberg; Jari Lahti; Dawn L. DeMeo; Hongmei Zhang; Wilfried Karmaus; Inger Kull; Berthold Koletzko; Jason I. Feinberg; Luigi Gagliardi; Luigi Bouchard; Cecilia Høst Ramlau-Hansen; Henning Tiemeier; Gillian Santorelli; Rachel L. Maguire; Darina Czamara; Augusto A. Litonjua; Jean Paul Langhendries; Michelle Plusquin; Johanna Lepeule; Elisabeth B. Binder; Elvira Verduci; Terence Dwyer; Ángel Carracedo; Natalia Ferre; Brenda Eskenazi; Manolis Kogevinas; Tim S. Nawrot; Monica C. Munthe-Kaas; Zdenko Herceg; Caroline Relton; Erik Melén; Dariusz Gruszfeld; Carrie Breton; M. D. Fallin; Akram Ghantous; Wenche Nystad; Barbara Heude; Harold Snieder; Marie France Hivert; Janine F. Felix; Thorkild I.A. Sørensen; Mariona Bustamante; Susan K. Murphy; Katri Räikkönen; Emily Oken; John W. Holloway; Syed Hasan Arshad; Stephanie J. London; Nina Holland

doi:10.1016/j.mrrev.2022.108415

Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

Olivia Solomon, Karen Huen, Paul Yousefi, Leanne K. Küpers, Juan R. González, Matthew Suderman, Sarah E. Reese, Christian M. Page, Olena Gruzieva, Peter Rzehak, Lu Gao, Kelly M. Bakulski, Alexei Novoloaca, Catherine Allard, Irene Pappa, Maria Llambrich, Marta Vives, Dereje D. Jima, Tuomas Kvist, Andrea BaccarelliCory White, Faisal I. Rezwan, Gemma C. Sharp, Gwen Tindula, Anna Bergström, Veit Grote, John F. Dou, Elena Isaevska, Maria C. Magnus, Eva Corpeleijn, Patrice Perron, Vincent W.V. Jaddoe, Ellen A. Nohr, Lea Maitre, Maria Foraster, Cathrine Hoyo, Siri E. Håberg, Jari Lahti, Dawn L. DeMeo, Hongmei Zhang, Wilfried Karmaus, Inger Kull, Berthold Koletzko, Jason I. Feinberg, Luigi Gagliardi, Luigi Bouchard, Cecilia Høst Ramlau-Hansen, Henning Tiemeier, Gillian Santorelli, Rachel L. Maguire, Darina Czamara, Augusto A. Litonjua, Jean Paul Langhendries, Michelle Plusquin, Johanna Lepeule, Elisabeth B. Binder, Elvira Verduci, Terence Dwyer, Ángel Carracedo, Natalia Ferre, Brenda Eskenazi, Manolis Kogevinas, Tim S. Nawrot, Monica C. Munthe-Kaas, Zdenko Herceg, Caroline Relton, Erik Melén, Dariusz Gruszfeld, Carrie Breton, M. D. Fallin, Akram Ghantous, Wenche Nystad, Barbara Heude, Harold Snieder, Marie France Hivert, Janine F. Felix, Thorkild I.A. Sørensen, Mariona Bustamante, Susan K. Murphy, Katri Räikkönen, Emily Oken, John W. Holloway, Syed Hasan Arshad, Stephanie J. London, Nina Holland

Tutkimustuotos: Artikkelijulkaisu › Katsausartikkeli › vertaisarvioitu

Alkuperäiskieli	englanti
Artikkeli	108415
Lehti	Mutation research. Reviews in mutation research
Vuosikerta	789
ISSN	1383-5742
DOI - pysyväislinkit	https://doi.org/10.1016/j.mrrev.2022.108415
Tila	Julkaistu - 1 tammik. 2022
OKM-julkaisutyyppi	A2 Katsausartikkeli tieteellisessä aikakauslehdessä

Lisätietoja

Funding Information:
For all studies, acknowledgments can be found in the Supplementary Material (Supplementary Methods).

Publisher Copyright:
© 2022 The Authors

Tieteenalat

3111 Biolääketieteet
3123 Naisten- ja lastentaudit

Pääsy asiakirjaan

10.1016/j.mrrev.2022.108415Lisenssi: CC BY-NC-ND

1-s2.0-S1383574222000059-mainLopullinen julkaistu versio, 3,24 MBLisenssi: CC BY-NC-ND

Siteeraa tätä

Solomon, O., Huen, K., Yousefi, P., Küpers, L. K., González, J. R., Suderman, M., Reese, S. E., Page, C. M., Gruzieva, O., Rzehak, P., Gao, L., Bakulski, K. M., Novoloaca, A., Allard, C., Pappa, I., Llambrich, M., Vives, M., Jima, D. D., Kvist, T., ... Holland, N. (2022). Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutation research. Reviews in mutation research, 789, Artikkeli 108415. https://doi.org/10.1016/j.mrrev.2022.108415

@article{62491eb7c7b942509b4b62fce9c33f21,

title = "Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation",

keywords = "Children, Cord blood, DNA methylation, EWAS, Sex, 3111 Biomedicine, 3123 Gynaecology and paediatrics",

author = "Olivia Solomon and Karen Huen and Paul Yousefi and K{\"u}pers, {Leanne K.} and Gonz{\'a}lez, {Juan R.} and Matthew Suderman and Reese, {Sarah E.} and Page, {Christian M.} and Olena Gruzieva and Peter Rzehak and Lu Gao and Bakulski, {Kelly M.} and Alexei Novoloaca and Catherine Allard and Irene Pappa and Maria Llambrich and Marta Vives and Jima, {Dereje D.} and Tuomas Kvist and Andrea Baccarelli and Cory White and Rezwan, {Faisal I.} and Sharp, {Gemma C.} and Gwen Tindula and Anna Bergstr{\"o}m and Veit Grote and Dou, {John F.} and Elena Isaevska and Magnus, {Maria C.} and Eva Corpeleijn and Patrice Perron and Jaddoe, {Vincent W.V.} and Nohr, {Ellen A.} and Lea Maitre and Maria Foraster and Cathrine Hoyo and H{\aa}berg, {Siri E.} and Jari Lahti and DeMeo, {Dawn L.} and Hongmei Zhang and Wilfried Karmaus and Inger Kull and Berthold Koletzko and Feinberg, {Jason I.} and Luigi Gagliardi and Luigi Bouchard and Ramlau-Hansen, {Cecilia H{\o}st} and Henning Tiemeier and Gillian Santorelli and Maguire, {Rachel L.} and Darina Czamara and Litonjua, {Augusto A.} and Langhendries, {Jean Paul} and Michelle Plusquin and Johanna Lepeule and Binder, {Elisabeth B.} and Elvira Verduci and Terence Dwyer and {\'A}ngel Carracedo and Natalia Ferre and Brenda Eskenazi and Manolis Kogevinas and Nawrot, {Tim S.} and Munthe-Kaas, {Monica C.} and Zdenko Herceg and Caroline Relton and Erik Mel{\'e}n and Dariusz Gruszfeld and Carrie Breton and Fallin, {M. D.} and Akram Ghantous and Wenche Nystad and Barbara Heude and Harold Snieder and Hivert, {Marie France} and Felix, {Janine F.} and S{\o}rensen, {Thorkild I.A.} and Mariona Bustamante and Murphy, {Susan K.} and Katri R{\"a}ikk{\"o}nen and Emily Oken and Holloway, {John W.} and Arshad, {Syed Hasan} and London, {Stephanie J.} and Nina Holland",

note = "Publisher Copyright: {\textcopyright} 2022 The Authors",

year = "2022",

month = jan,

day = "1",

doi = "10.1016/j.mrrev.2022.108415",

language = "English",

volume = "789",

journal = "Mutation research. Reviews in mutation research",

issn = "1383-5742",

publisher = "Elsevier B.V.",

}

Solomon, O, Huen, K, Yousefi, P, Küpers, LK, González, JR, Suderman, M, Reese, SE, Page, CM, Gruzieva, O, Rzehak, P, Gao, L, Bakulski, KM, Novoloaca, A, Allard, C, Pappa, I, Llambrich, M, Vives, M, Jima, DD, Kvist, T, Baccarelli, A, White, C, Rezwan, FI, Sharp, GC, Tindula, G, Bergström, A, Grote, V, Dou, JF, Isaevska, E, Magnus, MC, Corpeleijn, E, Perron, P, Jaddoe, VWV, Nohr, EA, Maitre, L, Foraster, M, Hoyo, C, Håberg, SE, Lahti, J, DeMeo, DL, Zhang, H, Karmaus, W, Kull, I, Koletzko, B, Feinberg, JI, Gagliardi, L, Bouchard, L, Ramlau-Hansen, CH, Tiemeier, H, Santorelli, G, Maguire, RL, Czamara, D, Litonjua, AA, Langhendries, JP, Plusquin, M, Lepeule, J, Binder, EB, Verduci, E, Dwyer, T, Carracedo, Á, Ferre, N, Eskenazi, B, Kogevinas, M, Nawrot, TS, Munthe-Kaas, MC, Herceg, Z, Relton, C, Melén, E, Gruszfeld, D, Breton, C, Fallin, MD, Ghantous, A, Nystad, W, Heude, B, Snieder, H, Hivert, MF, Felix, JF, Sørensen, TIA, Bustamante, M, Murphy, SK, Räikkönen, K, Oken, E, Holloway, JW, Arshad, SH, London, SJ & Holland, N 2022, 'Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation', Mutation research. Reviews in mutation research, Vuosikerta 789, 108415. https://doi.org/10.1016/j.mrrev.2022.108415

TY - JOUR

T1 - Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation

AU - Solomon, Olivia

AU - Huen, Karen

AU - Yousefi, Paul

AU - Küpers, Leanne K.

AU - González, Juan R.

AU - Suderman, Matthew

AU - Reese, Sarah E.

AU - Page, Christian M.

AU - Gruzieva, Olena

AU - Rzehak, Peter

AU - Gao, Lu

AU - Bakulski, Kelly M.

AU - Novoloaca, Alexei

AU - Allard, Catherine

AU - Pappa, Irene

AU - Llambrich, Maria

AU - Vives, Marta

AU - Jima, Dereje D.

AU - Kvist, Tuomas

AU - Baccarelli, Andrea

AU - White, Cory

AU - Rezwan, Faisal I.

AU - Sharp, Gemma C.

AU - Tindula, Gwen

AU - Bergström, Anna

AU - Grote, Veit

AU - Dou, John F.

AU - Isaevska, Elena

AU - Magnus, Maria C.

AU - Corpeleijn, Eva

AU - Perron, Patrice

AU - Jaddoe, Vincent W.V.

AU - Nohr, Ellen A.

AU - Maitre, Lea

AU - Foraster, Maria

AU - Hoyo, Cathrine

AU - Håberg, Siri E.

AU - Lahti, Jari

AU - DeMeo, Dawn L.

AU - Zhang, Hongmei

AU - Karmaus, Wilfried

AU - Kull, Inger

AU - Koletzko, Berthold

AU - Feinberg, Jason I.

AU - Gagliardi, Luigi

AU - Bouchard, Luigi

AU - Ramlau-Hansen, Cecilia Høst

AU - Tiemeier, Henning

AU - Santorelli, Gillian

AU - Maguire, Rachel L.

AU - Czamara, Darina

AU - Litonjua, Augusto A.

AU - Langhendries, Jean Paul

AU - Plusquin, Michelle

AU - Lepeule, Johanna

AU - Binder, Elisabeth B.

AU - Verduci, Elvira

AU - Dwyer, Terence

AU - Carracedo, Ángel

AU - Ferre, Natalia

AU - Eskenazi, Brenda

AU - Kogevinas, Manolis

AU - Nawrot, Tim S.

AU - Munthe-Kaas, Monica C.

AU - Herceg, Zdenko

AU - Relton, Caroline

AU - Melén, Erik

AU - Gruszfeld, Dariusz

AU - Breton, Carrie

AU - Fallin, M. D.

AU - Ghantous, Akram

AU - Nystad, Wenche

AU - Heude, Barbara

AU - Snieder, Harold

AU - Hivert, Marie France

AU - Felix, Janine F.

AU - Sørensen, Thorkild I.A.

AU - Bustamante, Mariona

AU - Murphy, Susan K.

AU - Räikkönen, Katri

AU - Oken, Emily

AU - Holloway, John W.

AU - Arshad, Syed Hasan

AU - London, Stephanie J.

AU - Holland, Nina

PY - 2022/1/1

Y1 - 2022/1/1

KW - Children

KW - Cord blood

KW - DNA methylation

KW - EWAS

KW - Sex

KW - 3111 Biomedicine

KW - 3123 Gynaecology and paediatrics

U2 - 10.1016/j.mrrev.2022.108415

DO - 10.1016/j.mrrev.2022.108415

M3 - Review Article

C2 - 35690418

AN - SCOPUS:85126865473

SN - 1383-5742

VL - 789

JO - Mutation research. Reviews in mutation research

JF - Mutation research. Reviews in mutation research

M1 - 108415

ER -