Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

Ian P. M. Tomlinson, Luis G. Carvajal-Carmona, Sara E. Dobbins, Albert Tenesa, Angela M. Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma E. M. Jaeger, Susan Farrington, Annabelle Lewis, James G. D. Prendergast, Alan M. Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin & 31 muut Stephane Ballereau, Amy Lloyd, Maggie Gorman, Steven Lubbe, Bryan Howie, Jonathan Marchini, Clara Ruiz-Ponte, Ceres Fernandez-Rozadilla, Antoni Castells, Angel Carracedo, Sergi Castellvi-Bel, David Duggan, David Conti, Jean-Baptiste Cazier, Harry Campbell, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G. Martin, Grant W. Montgomery, Joanne Young, Paul N. Baird, Steven Gallinger, Polly Newcomb, John Hopper, Mark A. Jenkins, Lauri A. Aaltonen, David J. Kerr, Jeremy Cheadle, Paul Pharoah, CORGI Collaborators, COGENT Consortium, EPICOLON Consortium

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

Alkuperäiskielienglanti
LehtiPLoS Genetics
Vuosikerta7
Numero6
Sivute1002105
Sivumäärä11
ISSN1553-7390
DOI - pysyväislinkit
TilaJulkaistu - 2011
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

  • 3122 Syöpätaudit

Lainaa tätä

Tomlinson, I. P. M., Carvajal-Carmona, L. G., Dobbins, S. E., Tenesa, A., Jones, A. M., Howarth, K., ... CORGI Collaborators, COGENT Consortium, EPICOLON Consortium (2011). Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer. PLoS Genetics, 7(6), e1002105. https://doi.org/10.1371/journal.pgen.1002105
Tomlinson, Ian P. M. ; Carvajal-Carmona, Luis G. ; Dobbins, Sara E. ; Tenesa, Albert ; Jones, Angela M. ; Howarth, Kimberley ; Palles, Claire ; Broderick, Peter ; Jaeger, Emma E. M. ; Farrington, Susan ; Lewis, Annabelle ; Prendergast, James G. D. ; Pittman, Alan M. ; Theodoratou, Evropi ; Olver, Bianca ; Walker, Marion ; Penegar, Steven ; Barclay, Ella ; Whiffin, Nicola ; Martin, Lynn ; Ballereau, Stephane ; Lloyd, Amy ; Gorman, Maggie ; Lubbe, Steven ; Howie, Bryan ; Marchini, Jonathan ; Ruiz-Ponte, Clara ; Fernandez-Rozadilla, Ceres ; Castells, Antoni ; Carracedo, Angel ; Castellvi-Bel, Sergi ; Duggan, David ; Conti, David ; Cazier, Jean-Baptiste ; Campbell, Harry ; Sieber, Oliver ; Lipton, Lara ; Gibbs, Peter ; Martin, Nicholas G. ; Montgomery, Grant W. ; Young, Joanne ; Baird, Paul N. ; Gallinger, Steven ; Newcomb, Polly ; Hopper, John ; Jenkins, Mark A. ; Aaltonen, Lauri A. ; Kerr, David J. ; Cheadle, Jeremy ; Pharoah, Paul ; CORGI Collaborators, COGENT Consortium, EPICOLON Consortium. / Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer. Julkaisussa: PLoS Genetics. 2011 ; Vuosikerta 7, Nro 6. Sivut e1002105.
@article{6facf3f5427f4c119e2a2cf3cadfa220,
title = "Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer",
keywords = "GENOME-WIDE ASSOCIATION, JUVENILE POLYPOSIS, GENETIC-VARIANTS, METAANALYSIS, RISK, MUTATIONS, TRIAL, 3122 Cancers",
author = "Tomlinson, {Ian P. M.} and Carvajal-Carmona, {Luis G.} and Dobbins, {Sara E.} and Albert Tenesa and Jones, {Angela M.} and Kimberley Howarth and Claire Palles and Peter Broderick and Jaeger, {Emma E. M.} and Susan Farrington and Annabelle Lewis and Prendergast, {James G. D.} and Pittman, {Alan M.} and Evropi Theodoratou and Bianca Olver and Marion Walker and Steven Penegar and Ella Barclay and Nicola Whiffin and Lynn Martin and Stephane Ballereau and Amy Lloyd and Maggie Gorman and Steven Lubbe and Bryan Howie and Jonathan Marchini and Clara Ruiz-Ponte and Ceres Fernandez-Rozadilla and Antoni Castells and Angel Carracedo and Sergi Castellvi-Bel and David Duggan and David Conti and Jean-Baptiste Cazier and Harry Campbell and Oliver Sieber and Lara Lipton and Peter Gibbs and Martin, {Nicholas G.} and Montgomery, {Grant W.} and Joanne Young and Baird, {Paul N.} and Steven Gallinger and Polly Newcomb and John Hopper and Jenkins, {Mark A.} and Aaltonen, {Lauri A.} and Kerr, {David J.} and Jeremy Cheadle and Paul Pharoah and {CORGI Collaborators, COGENT Consortium, EPICOLON Consortium}",
year = "2011",
doi = "10.1371/journal.pgen.1002105",
language = "English",
volume = "7",
pages = "e1002105",
journal = "PLoS Genetics",
issn = "1553-7390",
publisher = "PUBLIC LIBRARY OF SCIENCE",
number = "6",

}

Tomlinson, IPM, Carvajal-Carmona, LG, Dobbins, SE, Tenesa, A, Jones, AM, Howarth, K, Palles, C, Broderick, P, Jaeger, EEM, Farrington, S, Lewis, A, Prendergast, JGD, Pittman, AM, Theodoratou, E, Olver, B, Walker, M, Penegar, S, Barclay, E, Whiffin, N, Martin, L, Ballereau, S, Lloyd, A, Gorman, M, Lubbe, S, Howie, B, Marchini, J, Ruiz-Ponte, C, Fernandez-Rozadilla, C, Castells, A, Carracedo, A, Castellvi-Bel, S, Duggan, D, Conti, D, Cazier, J-B, Campbell, H, Sieber, O, Lipton, L, Gibbs, P, Martin, NG, Montgomery, GW, Young, J, Baird, PN, Gallinger, S, Newcomb, P, Hopper, J, Jenkins, MA, Aaltonen, LA, Kerr, DJ, Cheadle, J, Pharoah, P & CORGI Collaborators, COGENT Consortium, EPICOLON Consortium 2011, 'Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer', PLoS Genetics, Vuosikerta 7, Nro 6, Sivut e1002105. https://doi.org/10.1371/journal.pgen.1002105

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer. / Tomlinson, Ian P. M.; Carvajal-Carmona, Luis G.; Dobbins, Sara E.; Tenesa, Albert; Jones, Angela M.; Howarth, Kimberley; Palles, Claire; Broderick, Peter; Jaeger, Emma E. M.; Farrington, Susan; Lewis, Annabelle; Prendergast, James G. D.; Pittman, Alan M.; Theodoratou, Evropi; Olver, Bianca; Walker, Marion; Penegar, Steven; Barclay, Ella; Whiffin, Nicola; Martin, Lynn; Ballereau, Stephane; Lloyd, Amy; Gorman, Maggie; Lubbe, Steven; Howie, Bryan; Marchini, Jonathan; Ruiz-Ponte, Clara; Fernandez-Rozadilla, Ceres; Castells, Antoni; Carracedo, Angel; Castellvi-Bel, Sergi; Duggan, David; Conti, David; Cazier, Jean-Baptiste; Campbell, Harry; Sieber, Oliver; Lipton, Lara; Gibbs, Peter; Martin, Nicholas G.; Montgomery, Grant W.; Young, Joanne; Baird, Paul N.; Gallinger, Steven; Newcomb, Polly; Hopper, John; Jenkins, Mark A.; Aaltonen, Lauri A.; Kerr, David J.; Cheadle, Jeremy; Pharoah, Paul; CORGI Collaborators, COGENT Consortium, EPICOLON Consortium.

julkaisussa: PLoS Genetics, Vuosikerta 7, Nro 6, 2011, s. e1002105.

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

AU - Tomlinson, Ian P. M.

AU - Carvajal-Carmona, Luis G.

AU - Dobbins, Sara E.

AU - Tenesa, Albert

AU - Jones, Angela M.

AU - Howarth, Kimberley

AU - Palles, Claire

AU - Broderick, Peter

AU - Jaeger, Emma E. M.

AU - Farrington, Susan

AU - Lewis, Annabelle

AU - Prendergast, James G. D.

AU - Pittman, Alan M.

AU - Theodoratou, Evropi

AU - Olver, Bianca

AU - Walker, Marion

AU - Penegar, Steven

AU - Barclay, Ella

AU - Whiffin, Nicola

AU - Martin, Lynn

AU - Ballereau, Stephane

AU - Lloyd, Amy

AU - Gorman, Maggie

AU - Lubbe, Steven

AU - Howie, Bryan

AU - Marchini, Jonathan

AU - Ruiz-Ponte, Clara

AU - Fernandez-Rozadilla, Ceres

AU - Castells, Antoni

AU - Carracedo, Angel

AU - Castellvi-Bel, Sergi

AU - Duggan, David

AU - Conti, David

AU - Cazier, Jean-Baptiste

AU - Campbell, Harry

AU - Sieber, Oliver

AU - Lipton, Lara

AU - Gibbs, Peter

AU - Martin, Nicholas G.

AU - Montgomery, Grant W.

AU - Young, Joanne

AU - Baird, Paul N.

AU - Gallinger, Steven

AU - Newcomb, Polly

AU - Hopper, John

AU - Jenkins, Mark A.

AU - Aaltonen, Lauri A.

AU - Kerr, David J.

AU - Cheadle, Jeremy

AU - Pharoah, Paul

AU - CORGI Collaborators, COGENT Consortium, EPICOLON Consortium

PY - 2011

Y1 - 2011

KW - GENOME-WIDE ASSOCIATION

KW - JUVENILE POLYPOSIS

KW - GENETIC-VARIANTS

KW - METAANALYSIS

KW - RISK

KW - MUTATIONS

KW - TRIAL

KW - 3122 Cancers

U2 - 10.1371/journal.pgen.1002105

DO - 10.1371/journal.pgen.1002105

M3 - Article

VL - 7

SP - e1002105

JO - PLoS Genetics

JF - PLoS Genetics

SN - 1553-7390

IS - 6

ER -