Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats

Susanne Back; Julie Necarsulmer; Leslie R. Whitaker; Lamarque M. Coke; Pyry Koivula; Emily J. Heathward; Lowella Fortuno; Yajun Zhang; C. Grace Yeh; Heather A. Baldwin; Morgan D. Spencer; Carlos A. Mejias-Aponte; James Pickel; Alexander F. Hoffman; Charles E. Spivak; Carl R. Lupica; Suzanne M. Underhill; Susan G. Amara; Andrii Domanskyi; Jenni E. Anttila; Mikko Airavaara; Bruce T. Hope; F. Kent Hamra; Christopher T. Richie; Brandon K. Harvey

doi:10.1016/j.neuron.2019.01.035

Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats

Susanne Back, Julie Necarsulmer, Leslie R. Whitaker, Lamarque M. Coke, Pyry Koivula, Emily J. Heathward, Lowella Fortuno, Yajun Zhang, C. Grace Yeh, Heather A. Baldwin, Morgan D. Spencer, Carlos A. Mejias-Aponte, James Pickel, Alexander F. Hoffman, Charles E. Spivak, Carl R. Lupica, Suzanne M. Underhill, Susan G. Amara, Andrii Domanskyi, Jenni E. AnttilaMikko Airavaara, Bruce T. Hope, F. Kent Hamra, Christopher T. Richie, Brandon K. Harvey

Biotekniikan instituutti

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	Neuron
Vuosikerta	102
Numero	1
Sivut	105-+
Sivumäärä	23
ISSN	0896-6273
DOI - pysyväislinkit	https://doi.org/10.1016/j.neuron.2019.01.035
Tila	Julkaistu - 3 huhtik. 2019
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

3112 Neurotieteet

Pääsy asiakirjaan

10.1016/j.neuron.2019.01.035

Siteeraa tätä

Back, S., Necarsulmer, J., Whitaker, L. R., Coke, L. M., Koivula, P., Heathward, E. J., Fortuno, L., Zhang, Y., Yeh, C. G., Baldwin, H. A., Spencer, M. D., Mejias-Aponte, C. A., Pickel, J., Hoffman, A. F., Spivak, C. E., Lupica, C. R., Underhill, S. M., Amara, S. G., Domanskyi, A., ... Harvey, B. K. (2019). Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. Neuron, 102(1), 105-+. https://doi.org/10.1016/j.neuron.2019.01.035

Back, Susanne ; Necarsulmer, Julie ; Whitaker, Leslie R. ; Coke, Lamarque M. ; Koivula, Pyry ; Heathward, Emily J. ; Fortuno, Lowella ; Zhang, Yajun ; Yeh, C. Grace ; Baldwin, Heather A. ; Spencer, Morgan D. ; Mejias-Aponte, Carlos A. ; Pickel, James ; Hoffman, Alexander F. ; Spivak, Charles E. ; Lupica, Carl R. ; Underhill, Suzanne M. ; Amara, Susan G. ; Domanskyi, Andrii ; Anttila, Jenni E. ; Airavaara, Mikko ; Hope, Bruce T. ; Hamra, F. Kent ; Richie, Christopher T. ; Harvey, Brandon K. / Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. Julkaisussa: Neuron. 2019 ; Vuosikerta 102, Nro 1. Sivut 105-+.

@article{2d72f7bf86f145ec94d4e4574519e9fe,

title = "Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats",

keywords = "HOMOLOGY-DIRECTED REPAIR, ONE-STEP GENERATION, NEUROTROPHIC FACTOR, DOPAMINE RELEASE, MICE, RNA, CAS9, CRISPR/CAS9, EXPRESSION, MODELS, 3112 Neurosciences",

author = "Susanne Back and Julie Necarsulmer and Whitaker, {Leslie R.} and Coke, {Lamarque M.} and Pyry Koivula and Heathward, {Emily J.} and Lowella Fortuno and Yajun Zhang and Yeh, {C. Grace} and Baldwin, {Heather A.} and Spencer, {Morgan D.} and Mejias-Aponte, {Carlos A.} and James Pickel and Hoffman, {Alexander F.} and Spivak, {Charles E.} and Lupica, {Carl R.} and Underhill, {Suzanne M.} and Amara, {Susan G.} and Andrii Domanskyi and Anttila, {Jenni E.} and Mikko Airavaara and Hope, {Bruce T.} and Hamra, {F. Kent} and Richie, {Christopher T.} and Harvey, {Brandon K.}",

year = "2019",

month = apr,

day = "3",

doi = "10.1016/j.neuron.2019.01.035",

language = "English",

volume = "102",

pages = "105--+",

journal = "Neuron",

issn = "0896-6273",

publisher = "Cell Press",

number = "1",

}

Back, S, Necarsulmer, J, Whitaker, LR, Coke, LM, Koivula, P, Heathward, EJ, Fortuno, L, Zhang, Y, Yeh, CG, Baldwin, HA, Spencer, MD, Mejias-Aponte, CA, Pickel, J, Hoffman, AF, Spivak, CE, Lupica, CR, Underhill, SM, Amara, SG, Domanskyi, A , Anttila, JE , Airavaara, M, Hope, BT, Hamra, FK, Richie, CT & Harvey, BK 2019, 'Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats', Neuron, Vuosikerta 102, Nro 1, Sivut 105-+. https://doi.org/10.1016/j.neuron.2019.01.035

Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats. / Back, Susanne; Necarsulmer, Julie; Whitaker, Leslie R.; Coke, Lamarque M.; Koivula, Pyry; Heathward, Emily J.; Fortuno, Lowella; Zhang, Yajun; Yeh, C. Grace; Baldwin, Heather A.; Spencer, Morgan D.; Mejias-Aponte, Carlos A.; Pickel, James; Hoffman, Alexander F.; Spivak, Charles E.; Lupica, Carl R.; Underhill, Suzanne M.; Amara, Susan G.; Domanskyi, Andrii ; Anttila, Jenni E.; Airavaara, Mikko; Hope, Bruce T.; Hamra, F. Kent; Richie, Christopher T.; Harvey, Brandon K.

julkaisussa: Neuron, Vuosikerta 102, Nro 1, 03.04.2019, s. 105-+.

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Neuron-Specific Genome Modification in the Adult Rat Brain Using CRISPR-Cas9 Transgenic Rats

AU - Back, Susanne

AU - Necarsulmer, Julie

AU - Whitaker, Leslie R.

AU - Coke, Lamarque M.

AU - Koivula, Pyry

AU - Heathward, Emily J.

AU - Fortuno, Lowella

AU - Zhang, Yajun

AU - Yeh, C. Grace

AU - Baldwin, Heather A.

AU - Spencer, Morgan D.

AU - Mejias-Aponte, Carlos A.

AU - Pickel, James

AU - Hoffman, Alexander F.

AU - Spivak, Charles E.

AU - Lupica, Carl R.

AU - Underhill, Suzanne M.

AU - Amara, Susan G.

AU - Domanskyi, Andrii

AU - Anttila, Jenni E.

AU - Airavaara, Mikko

AU - Hope, Bruce T.

AU - Hamra, F. Kent

AU - Richie, Christopher T.

AU - Harvey, Brandon K.

PY - 2019/4/3

Y1 - 2019/4/3

KW - HOMOLOGY-DIRECTED REPAIR

KW - ONE-STEP GENERATION

KW - NEUROTROPHIC FACTOR

KW - DOPAMINE RELEASE

KW - MICE

KW - RNA

KW - CAS9

KW - CRISPR/CAS9

KW - EXPRESSION

KW - MODELS

KW - 3112 Neurosciences

U2 - 10.1016/j.neuron.2019.01.035

DO - 10.1016/j.neuron.2019.01.035

M3 - Article

VL - 102

SP - 105-+

JO - Neuron

JF - Neuron

SN - 0896-6273

IS - 1

ER -