PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis

Julia Perttilä; Carolina Huaman-Samanez; Sandrine Caron; Kimmo Tanhuanpaa; Bart Staels; Hannele Yki-Järvinen; Vesa Olkkonen

doi:10.1152/ajpendo.00125.2011

PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis

Julia Perttilä, Carolina Huaman-Samanez, Sandrine Caron, Kimmo Tanhuanpaa, Bart Staels, Hannele Yki-Järvinen, Vesa Olkkonen

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	American Journal of Physiology: Endocrinology and Metabolism
Vuosikerta	302
Numero	9
Sivut	E1063-E1069
Sivumäärä	7
ISSN	0193-1849
DOI - pysyväislinkit	https://doi.org/10.1152/ajpendo.00125.2011
Tila	Julkaistu - 2012
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

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3121 Yleislääketiede, sisätaudit ja muut kliiniset lääketieteet

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10.1152/ajpendo.00125.2011

Valomikroskopian teknologia-alusta / Valomikroskopiayksikkö
Kimmo Tanhuanpää (Johtaja)
Biotekniikan instituutti
Laitteistot/tilat: Keskuspalveluyksikkö

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Perttilä, Julia ; Huaman-Samanez, Carolina ; Caron, Sandrine ; Tanhuanpaa, Kimmo ; Staels, Bart ; Yki-Järvinen, Hannele ; Olkkonen, Vesa. / PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis. Julkaisussa: American Journal of Physiology: Endocrinology and Metabolism. 2012 ; Vuosikerta 302, Nro 9. Sivut E1063-E1069.

@article{53a09cfc3aa34e5e8bf4fe84cfd1e3b2,

title = "PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis",

keywords = "patatin-like phospholipase domain-containing 3, isoleucine to methionine change at position 148, NONALCOHOLIC FATTY LIVER, ELEMENT-BINDING PROTEIN, ADIPONUTRIN/PNPLA3 GENE, HISTOLOGICAL SEVERITY, DISEASE, VARIANT, SUSCEPTIBILITY, ASSOCIATION, METABOLISM, EXPRESSION, 3121 General medicine, internal medicine and other clinical medicine",

author = "Julia Perttil{\"a} and Carolina Huaman-Samanez and Sandrine Caron and Kimmo Tanhuanpaa and Bart Staels and Hannele Yki-J{\"a}rvinen and Vesa Olkkonen",

year = "2012",

doi = "10.1152/ajpendo.00125.2011",

language = "English",

volume = "302",

pages = "E1063--E1069",

journal = "American Journal of Physiology: Endocrinology and Metabolism",

issn = "0193-1849",

publisher = "American Physiological Society",

number = "9",

}

PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis. / Perttilä, Julia; Huaman-Samanez, Carolina; Caron, Sandrine; Tanhuanpaa, Kimmo; Staels, Bart; Yki-Järvinen, Hannele ; Olkkonen, Vesa.

julkaisussa: American Journal of Physiology: Endocrinology and Metabolism, Vuosikerta 302, Nro 9, 2012, s. E1063-E1069.

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis

AU - Perttilä, Julia

AU - Huaman-Samanez, Carolina

AU - Caron, Sandrine

AU - Tanhuanpaa, Kimmo

AU - Staels, Bart

AU - Yki-Järvinen, Hannele

AU - Olkkonen, Vesa

PY - 2012

Y1 - 2012

KW - patatin-like phospholipase domain-containing 3

KW - isoleucine to methionine change at position 148

KW - NONALCOHOLIC FATTY LIVER

KW - ELEMENT-BINDING PROTEIN

KW - ADIPONUTRIN/PNPLA3 GENE

KW - HISTOLOGICAL SEVERITY

KW - DISEASE

KW - VARIANT

KW - SUSCEPTIBILITY

KW - ASSOCIATION

KW - METABOLISM

KW - EXPRESSION

KW - 3121 General medicine, internal medicine and other clinical medicine

U2 - 10.1152/ajpendo.00125.2011

DO - 10.1152/ajpendo.00125.2011

M3 - Article

VL - 302

SP - E1063-E1069

JO - American Journal of Physiology: Endocrinology and Metabolism

JF - American Journal of Physiology: Endocrinology and Metabolism

SN - 0193-1849

IS - 9

ER -

PNPLA3 is regulated by glucose in human hepatocytes, and its I148M mutant slows down triglyceride hydrolysis

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Valomikroskopian teknologia-alusta / Valomikroskopiayksikkö

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