Preparation of N-​fluoropyrrolidin-​2-​ylmethoxy-​7-​oxo-​6-​(sulfooxy)​-​1,​6-​diazabicyclo[3.2.1]​octane-​2-​carboxamide derivatives as antibacterial compounds.

Piyush Patel, Vijaykumar Jagdishwar Patil, Ravikumar Tadiparthi, Rajib Bhuniya, Sachin Bhagwat, Swapna Shripad Takalkar, Rajesh Chavan, Anusuya Patel, Vipul Rane, Mahesh Vithalbhai. Patel

Tutkimustuotos: Patentti


Disclosed are compds. of formula I, their prepn., and use in preventing or treating a bacterial infection. Compds. of I [wherein R1 - R3 are independently H, CN, halo, aryl, etc.; n = 0, 1, 2, 3 or 4; M = H or cation] and stereoisomers, pharmaceutically acceptable salt thereof, are claimed and exemplified. Example compd. II was prepd. by a multistep procedure (prepn. given). Candidate compds. of I were evaluated for their antibacterial activity (data given). [on SciFinder(R)]
Julkaisuvuosi21 joulukuuta 2017
TilaJulkaistu - 21 joulukuuta 2017
OKM-julkaisutyyppiH1 Myönnetyt patentit


M1 - Copyright (C) 2019 American Chemical Society (ACS). All Rights Reserved.

CAPLUS AN 2017:2002960(Patent)

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