Rapid particle size measurement using 3D surface imaging

Ira Soppela, Sari Airaksinen, Juha Hatara, Heikki Räikkönen, Osmo Antikainen, Jouko Yliruusi, Niklas Sandler

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

Abstrakti

The present study introduces a new three-dimensional (3D) surface image analysis technique in which white light illumination from different incident angles is used to create 3D surfaces with a photometric approach. The three-dimensional features of the surface images created are then used in the characterization of particle size distributions of granules. This surface image analysis method is compared to sieve analysis and a particle sizing method based on spatial filtering technique with nearly 30 granule batches. The aim is also to evaluate the technique in flowability screening of granular materials. Overall, the new 3D imaging approach allows a rapid analysis of large amounts of sample and gives valuable visual information on the granule surfaces in terms of surface roughness and particle shape.
Alkuperäiskielienglanti
LehtiAAPS PharmSciTech
Vuosikerta12
Numero2
Sivut476-484
ISSN1530-9932
DOI - pysyväislinkit
TilaJulkaistu - huhtik. 2011
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

  • 317 Farmasia

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