Reduction mammaplasty- pre- and postoperative detection of breast cancer and lesions associated with increased risk

Reduction mammaplasty is one of the most common plastic surgery procedures. Variation exists between preoperative imaging and histopathology protocols in different countries and institutions. The aim of this study was to analyse the incidence of occult breast cancer and lesions associated with increased risk in reduction mammaplasty specimens, both in patients with or without a previous history of breast cancer. This study assessed whether patients with abnormal histopathology differed from the study population in terms of demographics. In addition, in patients with a previous history of breast cancer, it was analysed if timing of reduction mammaplasty with respect to oncological treatment influenced the incidence of abnormal findings in the specimens. This study described the imaging process and its ability to catch disease preoperatively. In addition, the association between imaging and histopathological findings in reduction mammaplasty specimens was examined. The 1255 women that underwent reduction mammaplasty between 1/2007 and 12/2011 were retrospectively reviewed for demographics, preoperative imaging, further preoperative examinations, histopathology reports, and postoperative follow-up. Among women with no previous history of breast cancer (n=918), abnormal histopathological findings were revealed in 88 (10.4%) patients. The incidence of breast cancer was 1.2% (n=10), and the incidence of high-risk lesions (atypical ductal hyperplasia, atypical lobular hyperplasia, and lobular carcinoma in situ) was 5.5% (n=47). Age (p