@article{9b3a8ab0338b4c48a4d3a47671eb3df1,
title = "Seed-effect modeling improves the consistency of genome-wide loss-of-function screens and identifies synthetic lethal vulnerabilities in cancer cells",
keywords = "RNAi screening, Gene essentiality, Seed essentiality, Off-target effects, Reproducibility, Seed effects, Synthetic lethality, Cancer cells, Precision oncology, RNA INTERFERENCE SCREENS, BREAST-CANCER, OVARIAN-CANCER, PI3K PATHWAY, GENE, REVEALS, CRISPR-CAS9, SUPPRESSION, DEPENDENCIES, CRISPR/CAS9, 3111 Biomedicine, 1184 Genetics, developmental biology, physiology",
author = "Alok Jaiswal and Gopal Peddinti and Yevhen Akimov and Krister Wennerberg and Sergey Kuznetsov and Jing Tang and Tero Aittokallio",
year = "2017",
month = jun,
day = "1",
doi = "10.1186/s13073-017-0440-2",
language = "English",
volume = "9",
journal = "Genome medicine",
issn = "1756-994X",
publisher = "BioMed Central Ltd",
}