Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation

Anna Tikka; Jarkko Soronen; Pirkka-Pekka Laurila; Jari Metso; Christian Ehnholm; Matti Jauhiainen

doi:10.1042/BSR20140115

Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation

Anna Tikka, Jarkko Soronen, Pirkka-Pekka Laurila, Jari Metso, Christian Ehnholm, Matti Jauhiainen

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Artikkeli	00160
Lehti	Bioscience Reports
Vuosikerta	34
Sivut	811-821
Sivumäärä	11
ISSN	0144-8463
DOI - pysyväislinkit	https://doi.org/10.1042/BSR20140115
Tila	Julkaistu - 2014
Julkaistu ulkoisesti	Kyllä
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

3111 Biolääketieteet

Pääsy asiakirjaan

10.1042/BSR20140115

Muut tiedostot ja linkit

Link to publication in Scopus

Siteeraa tätä

Tikka, A., Soronen, J., Laurila, P.-P., Metso, J., Ehnholm, C., & Jauhiainen, M. (2014). Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation. Bioscience Reports, 34, 811-821. Artikkeli 00160. https://doi.org/10.1042/BSR20140115

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title = "Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation",

keywords = "ANGPTL3 silencing, hypolipidaemia, insulin signalling, liver, rosiglitazone, VLDL, FAMILIAL COMBINED HYPOLIPIDEMIA, LIPOPROTEIN-LIPASE ACTIVITY, ACTIVATED RECEPTOR-GAMMA, IN-VIVO, HEPATIC GLUCONEOGENESIS, PEROXISOME PROLIFERATOR, LIPID-METABOLISM, LIVER, RESISTANCE, MICE, 3111 Biomedicine",

author = "Anna Tikka and Jarkko Soronen and Pirkka-Pekka Laurila and Jari Metso and Christian Ehnholm and Matti Jauhiainen",

year = "2014",

doi = "10.1042/BSR20140115",

language = "English",

volume = "34",

pages = "811--821",

journal = "Bioscience Reports",

issn = "0144-8463",

publisher = "Portland Press Ltd.",

}

Tikka, A, Soronen, J, Laurila, P-P, Metso, J, Ehnholm, C & Jauhiainen, M 2014, 'Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation', Bioscience Reports, Vuosikerta 34, 00160, Sivut 811-821. https://doi.org/10.1042/BSR20140115

Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation. / Tikka, Anna; Soronen, Jarkko; Laurila, Pirkka-Pekka et al.
julkaisussa: Bioscience Reports, Vuosikerta 34, 00160, 2014, s. 811-821.

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

TY - JOUR

T1 - Silencing of ANGPTL 3 (angiopoietin-like protein 3) in human hepatocytes results in decreased expression of gluconeogenic genes and reduced triacylglycerol-rich VLDL secretion upon insulin stimulation

AU - Tikka, Anna

AU - Soronen, Jarkko

AU - Laurila, Pirkka-Pekka

AU - Metso, Jari

AU - Ehnholm, Christian

AU - Jauhiainen, Matti

PY - 2014

Y1 - 2014

KW - ANGPTL3 silencing

KW - hypolipidaemia

KW - insulin signalling

KW - liver

KW - rosiglitazone

KW - VLDL

KW - FAMILIAL COMBINED HYPOLIPIDEMIA

KW - LIPOPROTEIN-LIPASE ACTIVITY

KW - ACTIVATED RECEPTOR-GAMMA

KW - IN-VIVO

KW - HEPATIC GLUCONEOGENESIS

KW - PEROXISOME PROLIFERATOR

KW - LIPID-METABOLISM

KW - LIVER

KW - RESISTANCE

KW - MICE

KW - 3111 Biomedicine

UR - https://www.scopus.com/pages/publications/84919624492

U2 - 10.1042/BSR20140115

DO - 10.1042/BSR20140115

M3 - Article

SN - 0144-8463

VL - 34

SP - 811

EP - 821

JO - Bioscience Reports

JF - Bioscience Reports

M1 - 00160

ER -