Single embryo transfer: why and how to identify the embryo with the best developmental potential

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

Kuvaus

Multiple pregnancies with higher risk of preterm birth and the associated higher morbidity have been a major obstacle from the early days of in vitro fertilization. A good strategy to avoid multiple pregnancies is elective single embryo transfer and cryopreservation of spare embryos. Important factors in adopting this strategy are good counselling of the patients and the selection of embryos with high implantation potential. Technical advances in embryo selection have been described during recent years, time lapse monitoring and genetic assessment of the embryos being the most important achievements. With these studies we have gained new information on early embryos. However, at present, there is insufficient evidence to recommend the routine use of these new techniques. The ultimate goal of infertility treatment is a healthy baby.
Alkuperäiskielienglanti
LehtiBest Practice & Research. Clinical Endocrinology & Metabolism
ISSN1521-690X
DOI - pysyväislinkit
TilaJulkaistu - 13 huhtikuuta 2019
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

  • 3123 Naisten- ja lastentaudit

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title = "Single embryo transfer: why and how to identify the embryo with the best developmental potential",
abstract = "Multiple pregnancies with higher risk of preterm birth and the associated higher morbidity have been a major obstacle from the early days of in vitro fertilization. A good strategy to avoid multiple pregnancies is elective single embryo transfer and cryopreservation of spare embryos. Important factors in adopting this strategy are good counselling of the patients and the selection of embryos with high implantation potential. Technical advances in embryo selection have been described during recent years, time lapse monitoring and genetic assessment of the embryos being the most important achievements. With these studies we have gained new information on early embryos. However, at present, there is insufficient evidence to recommend the routine use of these new techniques. The ultimate goal of infertility treatment is a healthy baby.",
keywords = "Assisted reproduction technology (ART), in vitro fertilization (IVF), cryopreservation, elective single embryo transfer (eSET), time lapse monitoring, preimplantation genetic testing for aneuploidy (PGT-A), 3123 Gynaecology and paediatrics",
author = "Aila Tiitinen",
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doi = "10.1016/j.beem.2019.04.001",
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Single embryo transfer: why and how to identify the embryo with the best developmental potential. / Tiitinen, Aila.

julkaisussa: Best Practice & Research. Clinical Endocrinology & Metabolism, 13.04.2019.

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Single embryo transfer: why and how to identify the embryo with the best developmental potential

AU - Tiitinen, Aila

PY - 2019/4/13

Y1 - 2019/4/13

N2 - Multiple pregnancies with higher risk of preterm birth and the associated higher morbidity have been a major obstacle from the early days of in vitro fertilization. A good strategy to avoid multiple pregnancies is elective single embryo transfer and cryopreservation of spare embryos. Important factors in adopting this strategy are good counselling of the patients and the selection of embryos with high implantation potential. Technical advances in embryo selection have been described during recent years, time lapse monitoring and genetic assessment of the embryos being the most important achievements. With these studies we have gained new information on early embryos. However, at present, there is insufficient evidence to recommend the routine use of these new techniques. The ultimate goal of infertility treatment is a healthy baby.

AB - Multiple pregnancies with higher risk of preterm birth and the associated higher morbidity have been a major obstacle from the early days of in vitro fertilization. A good strategy to avoid multiple pregnancies is elective single embryo transfer and cryopreservation of spare embryos. Important factors in adopting this strategy are good counselling of the patients and the selection of embryos with high implantation potential. Technical advances in embryo selection have been described during recent years, time lapse monitoring and genetic assessment of the embryos being the most important achievements. With these studies we have gained new information on early embryos. However, at present, there is insufficient evidence to recommend the routine use of these new techniques. The ultimate goal of infertility treatment is a healthy baby.

KW - Assisted reproduction technology (ART)

KW - in vitro fertilization (IVF)

KW - cryopreservation

KW - elective single embryo transfer (eSET)

KW - time lapse monitoring

KW - preimplantation genetic testing for aneuploidy (PGT-A)

KW - 3123 Gynaecology and paediatrics

U2 - 10.1016/j.beem.2019.04.001

DO - 10.1016/j.beem.2019.04.001

M3 - Article

JO - Best Practice & Research. Clinical Endocrinology & Metabolism

JF - Best Practice & Research. Clinical Endocrinology & Metabolism

SN - 1521-690X

ER -