Stability and change of body mass index as a predictor of disability

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

Kuvaus

AIMS:

To investigate whether stability or change in body mass index (BMI) predict disability pension (DP) due to musculoskeletal diagnosis (MSD) when controlling for familial confounding.

METHODS:

Our study cohort consisted of 17,169 Finnish twins born before 1958. Data on BMI and multiple covariates from questionnaires in 1975 and 1981 were included and DPs were collected from the national pension registers until the end of 2004. Cox proportional hazards regression models with Hazard Ratios (HR) and 95% Confidence Intervals (CI) were used for statistical analyses.

RESULTS:

General DP was granted to 2853 individuals and DP due to MSD to 1143 individuals during the 23-year follow-up. A one-unit increase in BMI in both 1975 (HR 1.08, 95% CI 1.05, 1.10) and 1981 (HR 1.06, 95% CI 1.04, 1.07), as well as the stability of and change in BMI from 1975 to 1981 were all associated with an increased risk of DP. These associations held in the analyses controlling for multiple covariates (age, sex, socioeconomic status, education, marital status, leisure-time physical activity, and musculoskeletal pain), and mainly also familial confounding, that is, genetics and shared environment. HR for stable obesity was 2.28 (95% CI 1.69, 3.08) for DP due to MSD, and 1.91 (95% CI 1.56, 2.34) for general DP in the fully adjusted models.

CONCLUSIONS:

BMI is an early predictor of general DP and also of DP due to MSD. Owing to the independency of various covariates and potentially also familial confounding, BMI may possibly have a direct effect on the risk of DP.
Alkuperäiskielienglanti
LehtiScandinavian Journal of Public Health
Vuosikerta44
Numero4
Sivut369-376
ISSN1403-4948
DOI - pysyväislinkit
TilaJulkaistu - 19 tammikuuta 2016
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

  • 3142 Kansanterveystiede, ympäristö ja työterveys

Lainaa tätä

@article{d24de80580a14e5988e1782ac8cebec8,
title = "Stability and change of body mass index as a predictor of disability",
abstract = "AIMS: To investigate whether stability or change in body mass index (BMI) predict disability pension (DP) due to musculoskeletal diagnosis (MSD) when controlling for familial confounding.METHODS: Our study cohort consisted of 17,169 Finnish twins born before 1958. Data on BMI and multiple covariates from questionnaires in 1975 and 1981 were included and DPs were collected from the national pension registers until the end of 2004. Cox proportional hazards regression models with Hazard Ratios (HR) and 95{\%} Confidence Intervals (CI) were used for statistical analyses.RESULTS: General DP was granted to 2853 individuals and DP due to MSD to 1143 individuals during the 23-year follow-up. A one-unit increase in BMI in both 1975 (HR 1.08, 95{\%} CI 1.05, 1.10) and 1981 (HR 1.06, 95{\%} CI 1.04, 1.07), as well as the stability of and change in BMI from 1975 to 1981 were all associated with an increased risk of DP. These associations held in the analyses controlling for multiple covariates (age, sex, socioeconomic status, education, marital status, leisure-time physical activity, and musculoskeletal pain), and mainly also familial confounding, that is, genetics and shared environment. HR for stable obesity was 2.28 (95{\%} CI 1.69, 3.08) for DP due to MSD, and 1.91 (95{\%} CI 1.56, 2.34) for general DP in the fully adjusted models.CONCLUSIONS: BMI is an early predictor of general DP and also of DP due to MSD. Owing to the independency of various covariates and potentially also familial confounding, BMI may possibly have a direct effect on the risk of DP.",
keywords = "3142 Public health care science, environmental and occupational health, sickness absence, body mass index, disability pension, musculoskeletal disorders, prospective design",
author = "Annina Ropponen and Silventoinen, {Karri Tapani} and Koskenvuo, {Markku Juhani} and Pia Svedberg and Kaprio, {Jaakko Arthur}",
year = "2016",
month = "1",
day = "19",
doi = "10.1177/1403494815622849",
language = "English",
volume = "44",
pages = "369--376",
journal = "Scandinavian Journal of Public Health",
issn = "1403-4948",
publisher = "SAGE Publications Ltd STM",
number = "4",

}

Stability and change of body mass index as a predictor of disability. / Ropponen, Annina; Silventoinen, Karri Tapani; Koskenvuo, Markku Juhani; Svedberg, Pia; Kaprio, Jaakko Arthur.

julkaisussa: Scandinavian Journal of Public Health, Vuosikerta 44, Nro 4, 19.01.2016, s. 369-376.

Tutkimustuotos: ArtikkelijulkaisuArtikkeliTieteellinenvertaisarvioitu

TY - JOUR

T1 - Stability and change of body mass index as a predictor of disability

AU - Ropponen, Annina

AU - Silventoinen, Karri Tapani

AU - Koskenvuo, Markku Juhani

AU - Svedberg, Pia

AU - Kaprio, Jaakko Arthur

PY - 2016/1/19

Y1 - 2016/1/19

N2 - AIMS: To investigate whether stability or change in body mass index (BMI) predict disability pension (DP) due to musculoskeletal diagnosis (MSD) when controlling for familial confounding.METHODS: Our study cohort consisted of 17,169 Finnish twins born before 1958. Data on BMI and multiple covariates from questionnaires in 1975 and 1981 were included and DPs were collected from the national pension registers until the end of 2004. Cox proportional hazards regression models with Hazard Ratios (HR) and 95% Confidence Intervals (CI) were used for statistical analyses.RESULTS: General DP was granted to 2853 individuals and DP due to MSD to 1143 individuals during the 23-year follow-up. A one-unit increase in BMI in both 1975 (HR 1.08, 95% CI 1.05, 1.10) and 1981 (HR 1.06, 95% CI 1.04, 1.07), as well as the stability of and change in BMI from 1975 to 1981 were all associated with an increased risk of DP. These associations held in the analyses controlling for multiple covariates (age, sex, socioeconomic status, education, marital status, leisure-time physical activity, and musculoskeletal pain), and mainly also familial confounding, that is, genetics and shared environment. HR for stable obesity was 2.28 (95% CI 1.69, 3.08) for DP due to MSD, and 1.91 (95% CI 1.56, 2.34) for general DP in the fully adjusted models.CONCLUSIONS: BMI is an early predictor of general DP and also of DP due to MSD. Owing to the independency of various covariates and potentially also familial confounding, BMI may possibly have a direct effect on the risk of DP.

AB - AIMS: To investigate whether stability or change in body mass index (BMI) predict disability pension (DP) due to musculoskeletal diagnosis (MSD) when controlling for familial confounding.METHODS: Our study cohort consisted of 17,169 Finnish twins born before 1958. Data on BMI and multiple covariates from questionnaires in 1975 and 1981 were included and DPs were collected from the national pension registers until the end of 2004. Cox proportional hazards regression models with Hazard Ratios (HR) and 95% Confidence Intervals (CI) were used for statistical analyses.RESULTS: General DP was granted to 2853 individuals and DP due to MSD to 1143 individuals during the 23-year follow-up. A one-unit increase in BMI in both 1975 (HR 1.08, 95% CI 1.05, 1.10) and 1981 (HR 1.06, 95% CI 1.04, 1.07), as well as the stability of and change in BMI from 1975 to 1981 were all associated with an increased risk of DP. These associations held in the analyses controlling for multiple covariates (age, sex, socioeconomic status, education, marital status, leisure-time physical activity, and musculoskeletal pain), and mainly also familial confounding, that is, genetics and shared environment. HR for stable obesity was 2.28 (95% CI 1.69, 3.08) for DP due to MSD, and 1.91 (95% CI 1.56, 2.34) for general DP in the fully adjusted models.CONCLUSIONS: BMI is an early predictor of general DP and also of DP due to MSD. Owing to the independency of various covariates and potentially also familial confounding, BMI may possibly have a direct effect on the risk of DP.

KW - 3142 Public health care science, environmental and occupational health

KW - sickness absence

KW - body mass index

KW - disability pension

KW - musculoskeletal disorders

KW - prospective design

U2 - 10.1177/1403494815622849

DO - 10.1177/1403494815622849

M3 - Article

VL - 44

SP - 369

EP - 376

JO - Scandinavian Journal of Public Health

JF - Scandinavian Journal of Public Health

SN - 1403-4948

IS - 4

ER -