Stereoselective Synthesis of Alfa-5-halo-2’-deoxyuridines

Tom Erik Lagerwall; Petri Heinonen; Mikko Oivanen

Stereoselective Synthesis of Alfa-5-halo-2’-deoxyuridines

Julkaisun otsikon käännös: Alfa-5-halo-2'-deoksiuridiinien stereoselektiivinen synteesi

Tom Erik Lagerwall, Petri Heinonen, Mikko Oivanen

Kemian osasto

Tutkimustuotos: Artikkeli kirjassa/raportissa/konferenssijulkaisussa › Konferenssiartikkeli › Tieteellinen

Abstrakti

Reversed stereoselectivity is observed, when 5-halouracils are used in place of uracil or thymine in gly-cosidation with 2-deoxy-D-ribose having a β/α-directing 3-O-protection. Several 5-halo-2’-deoxyuridine deriva-tives have been synthesized and the effects on the β/α-ratio are analysed.

Julkaisun otsikon käännös	Alfa-5-halo-2'-deoksiuridiinien stereoselektiivinen synteesi
Alkuperäiskieli	englanti
Otsikko	XX International Round Table on Nucleosides, Nucleotides & Nucleic Acids
Sivumäärä	1
Julkaisupäivä	2012
Tila	Julkaistu - 2012
OKM-julkaisutyyppi	B3 Vertaisarvioimaton artikkeli konferenssijulkaisussa
Tapahtuma	International Round Table - Montréal, Kanada Kesto: 5 elok. 2012 → 9 elok. 2012 Konferenssinumero: 20

Tieteenalat

116 Kemia
nukleiinihappojen synteesi
stereselektiivinen synteesi

Siteeraa tätä

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title = "Stereoselective Synthesis of Alfa-5-halo-2{\textquoteright}-deoxyuridines",

abstract = "Reversed stereoselectivity is observed, when 5-halouracils are used in place of uracil or thymine in gly-cosidation with 2-deoxy-D-ribose having a β/α-directing 3-O-protection. Several 5-halo-2{\textquoteright}-deoxyuridine deriva-tives have been synthesized and the effects on the β/α-ratio are analysed.",

keywords = "116 Chemical sciences, nukleiinihappojen synteesi, stereselektiivinen synteesi",

author = "Lagerwall, {Tom Erik} and Petri Heinonen and Mikko Oivanen",

year = "2012",

language = "English",

booktitle = "XX International Round Table on Nucleosides, Nucleotides & Nucleic Acids",

note = "International Round Table ; Conference date: 05-08-2012 Through 09-08-2012",

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TY - GEN

T1 - Stereoselective Synthesis of Alfa-5-halo-2’-deoxyuridines

AU - Lagerwall, Tom Erik

AU - Heinonen, Petri

AU - Oivanen, Mikko

N1 - Conference code: 20

PY - 2012

Y1 - 2012

N2 - Reversed stereoselectivity is observed, when 5-halouracils are used in place of uracil or thymine in gly-cosidation with 2-deoxy-D-ribose having a β/α-directing 3-O-protection. Several 5-halo-2’-deoxyuridine deriva-tives have been synthesized and the effects on the β/α-ratio are analysed.

AB - Reversed stereoselectivity is observed, when 5-halouracils are used in place of uracil or thymine in gly-cosidation with 2-deoxy-D-ribose having a β/α-directing 3-O-protection. Several 5-halo-2’-deoxyuridine deriva-tives have been synthesized and the effects on the β/α-ratio are analysed.

KW - 116 Chemical sciences

KW - nukleiinihappojen synteesi

KW - stereselektiivinen synteesi

M3 - Conference contribution

BT - XX International Round Table on Nucleosides, Nucleotides & Nucleic Acids

T2 - International Round Table

Y2 - 5 August 2012 through 9 August 2012

ER -