Targeting peptides, a Swiss-army knife against cancer

Tutkimustuotos: Artikkeli kirjassa/raportissa/konferenssijulkaisussaKirjan luku tai artikkeliTieteellinenvertaisarvioitu

Kuvaus

Characterised by both great selectivity and flexibility, peptides are also considered safe and usually quite well tolerated by patients. During the past two decades, development of anti-cancer peptide therapeutics has formed sustained activity in the research and development (R&D) departments of pharmaceutical industry. Cancer is the emerging leading cause of death worldwide often without a satisfactory therapeutic option available. To overcome the often-acquired chemotherapeutic resistance and side effects, novel drugs that are specifically attacking cancer cells and less toxic to normal cells are required. Thus, tumour targeting peptides constitute an appealing tool for cancer detection and treatment. In this chapter, we will summarise the identification of novel cancer targeting peptides and also address some of the most promising candidates currently under preclinical investigation.
Alkuperäiskielienglanti
OtsikkoAmino Acids, Peptides and Proteins
ToimittajatMaxim Ryadnov, Ferenc Hudecz
Sivumäärä40
Vuosikerta42
KustantajaRoyal Society of Chemistry
Julkaisupäivä2018
Sivut281-320
ISBN (painettu)978-1-78801-002-3
ISBN (elektroninen)978-1-78801-062-7
DOI - pysyväislinkit
TilaJulkaistu - 2018
OKM-julkaisutyyppiA3 Kirjan tai muun kokoomateoksen osa

Tieteenalat

  • 413 Eläinlääketiede

Lainaa tätä

Le Joncour, V. J. M., & Laakkonen, P. (2018). Targeting peptides, a Swiss-army knife against cancer. teoksessa M. Ryadnov, & F. Hudecz (Toimittajat), Amino Acids, Peptides and Proteins (Vuosikerta 42, Sivut 281-320). Royal Society of Chemistry. https://doi.org/10.1039/9781788010627-00280
Le Joncour, Vadim Jacques Mara ; Laakkonen, Pirjo . / Targeting peptides, a Swiss-army knife against cancer. Amino Acids, Peptides and Proteins. Toimittaja / Maxim Ryadnov ; Ferenc Hudecz. Vuosikerta 42 Royal Society of Chemistry, 2018. Sivut 281-320
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Le Joncour, VJM & Laakkonen, P 2018, Targeting peptides, a Swiss-army knife against cancer. julkaisussa M Ryadnov & F Hudecz (toim), Amino Acids, Peptides and Proteins. Vuosikerta 42, Royal Society of Chemistry, Sivut 281-320. https://doi.org/10.1039/9781788010627-00280

Targeting peptides, a Swiss-army knife against cancer. / Le Joncour, Vadim Jacques Mara; Laakkonen, Pirjo .

Amino Acids, Peptides and Proteins. toim. / Maxim Ryadnov; Ferenc Hudecz. Vuosikerta 42 Royal Society of Chemistry, 2018. s. 281-320.

Tutkimustuotos: Artikkeli kirjassa/raportissa/konferenssijulkaisussaKirjan luku tai artikkeliTieteellinenvertaisarvioitu

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PY - 2018

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N2 - Characterised by both great selectivity and flexibility, peptides are also considered safe and usually quite well tolerated by patients. During the past two decades, development of anti-cancer peptide therapeutics has formed sustained activity in the research and development (R&D) departments of pharmaceutical industry. Cancer is the emerging leading cause of death worldwide often without a satisfactory therapeutic option available. To overcome the often-acquired chemotherapeutic resistance and side effects, novel drugs that are specifically attacking cancer cells and less toxic to normal cells are required. Thus, tumour targeting peptides constitute an appealing tool for cancer detection and treatment. In this chapter, we will summarise the identification of novel cancer targeting peptides and also address some of the most promising candidates currently under preclinical investigation.

AB - Characterised by both great selectivity and flexibility, peptides are also considered safe and usually quite well tolerated by patients. During the past two decades, development of anti-cancer peptide therapeutics has formed sustained activity in the research and development (R&D) departments of pharmaceutical industry. Cancer is the emerging leading cause of death worldwide often without a satisfactory therapeutic option available. To overcome the often-acquired chemotherapeutic resistance and side effects, novel drugs that are specifically attacking cancer cells and less toxic to normal cells are required. Thus, tumour targeting peptides constitute an appealing tool for cancer detection and treatment. In this chapter, we will summarise the identification of novel cancer targeting peptides and also address some of the most promising candidates currently under preclinical investigation.

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Le Joncour VJM, Laakkonen P. Targeting peptides, a Swiss-army knife against cancer. julkaisussa Ryadnov M, Hudecz F, toimittajat, Amino Acids, Peptides and Proteins. Vuosikerta 42. Royal Society of Chemistry. 2018. s. 281-320 https://doi.org/10.1039/9781788010627-00280