The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency

P. Sipilä; A. Junnila; J. Hakkarainen; R. Huhtaniemi; L. Mairinoja; F. P. Zhang; L. Strauss; C. Ohlsson; N. Kotaja; I. Huhtaniemi; M. Poutanen

doi:10.1096/fj.201902384R

The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency

P. Sipilä
, A. Junnila
, J. Hakkarainen
, R. Huhtaniemi
, L. Mairinoja
, F. P. Zhang
, L. Strauss
, C. Ohlsson
, N. Kotaja
, I. Huhtaniemi
, M. Poutanen

Tutkimustuotos: Artikkelijulkaisu › Artikkeli › Tieteellinen › vertaisarvioitu

Alkuperäiskieli	englanti
Lehti	FASEB Journal
Vuosikerta	34
Numero	5
Sivut	6111-6128
Sivumäärä	18
ISSN	0892-6638
DOI - pysyväislinkit	https://doi.org/10.1096/fj.201902384R
Tila	Julkaistu - toukok. 2020
Julkaistu ulkoisesti	Kyllä
OKM-julkaisutyyppi	A1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä, vertaisarvioitu

Tieteenalat

1182 Biokemia, solu- ja molekyylibiologia

Pääsy asiakirjaan

10.1096/fj.201902384R

Siteeraa tätä

Sipilä, P., Junnila, A., Hakkarainen, J., Huhtaniemi, R., Mairinoja, L., Zhang, F. P., Strauss, L., Ohlsson, C., Kotaja, N., Huhtaniemi, I., & Poutanen, M. (2020). The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency. FASEB Journal, 34(5), 6111-6128. https://doi.org/10.1096/fj.201902384R

@article{e2d52d50e81748fa9e00605b348dad27,

title = "The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency",

keywords = "1182 Biochemistry, cell and molecular biology, disorder of sex development, HSD17B3, Leydig cell maturation, LUTEINIZING-HORMONE RECEPTOR, DIAGNOSIS, 17-BETA-HYDROXYSTEROID-DEHYDROGENASE 3 DEFICIENCY, DEHYDROGENASE-DEFICIENCY, MODELS, TISSUE, GERM, MALE PSEUDOHERMAPHRODITISM, EXPRESSION",

author = "P. Sipil{\"a} and A. Junnila and J. Hakkarainen and R. Huhtaniemi and L. Mairinoja and Zhang, \{F. P.\} and L. Strauss and C. Ohlsson and N. Kotaja and I. Huhtaniemi and M. Poutanen",

year = "2020",

month = may,

doi = "10.1096/fj.201902384R",

language = "English",

volume = "34",

pages = "6111--6128",

journal = "FASEB Journal",

issn = "0892-6638",

publisher = "John Wiley \& Sons Ltd. ",

number = "5",

}

Sipilä, P, Junnila, A, Hakkarainen, J, Huhtaniemi, R, Mairinoja, L, Zhang, FP, Strauss, L, Ohlsson, C, Kotaja, N, Huhtaniemi, I & Poutanen, M 2020, 'The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency', FASEB Journal, Vuosikerta 34, Nro 5, Sivut 6111-6128. https://doi.org/10.1096/fj.201902384R

TY - JOUR

T1 - The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency

AU - Sipilä, P.

AU - Junnila, A.

AU - Hakkarainen, J.

AU - Huhtaniemi, R.

AU - Mairinoja, L.

AU - Zhang, F. P.

AU - Strauss, L.

AU - Ohlsson, C.

AU - Kotaja, N.

AU - Huhtaniemi, I.

AU - Poutanen, M.

PY - 2020/5

Y1 - 2020/5

KW - 1182 Biochemistry, cell and molecular biology

KW - disorder of sex development

KW - HSD17B3

KW - Leydig cell maturation

KW - LUTEINIZING-HORMONE RECEPTOR

KW - DIAGNOSIS

KW - 17-BETA-HYDROXYSTEROID-DEHYDROGENASE 3 DEFICIENCY

KW - DEHYDROGENASE-DEFICIENCY

KW - MODELS

KW - TISSUE

KW - GERM

KW - MALE PSEUDOHERMAPHRODITISM

KW - EXPRESSION

U2 - 10.1096/fj.201902384R

DO - 10.1096/fj.201902384R

M3 - Article

C2 - 32190925

SN - 0892-6638

VL - 34

SP - 6111

EP - 6128

JO - FASEB Journal

JF - FASEB Journal

IS - 5

ER -