The phylodynamics of SARS-CoV-2 during 2020 in Finland — Disappearance and re-emergence of introduced strains.

Phuoc Truong Nguyen, Ravi Kant, Frederik Van den Broeck, Maija T. Suvanto, Hussein Alburkat, Jenni Virtanen, Ella Ahvenainen, Robert Castren, Samuel L. Hong, Guy Baele, Maarit J. Ahava, Hanna Jarva, Suvi Tuulia Jokiranta, Hannimari Kallio-Kokko, Eliisa Kekäläinen, Vesa Kirjavainen, Elisa Kortela, Satu Kurkela, Maija Lappalainen, Hanna LiimatainenMarc A. Suchard, Sari Hannula, Pekka Ellonen, Tarja Sironen, Philippe Lemey, Olli Vapalahti, Teemu Smura

Tutkimustuotos: ArtikkelijulkaisuArtikkeli

Abstrakti

Finland has had a low incidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infections as compared to most European countries. Here we report the origins and turnover of SARS-CoV-2 lineages circulating in Finland in 2020. SARS-CoV-2 introduced to Finland in January 2020 and spread rapidly across southern Finland during spring. We observed rapid turnover among Finnish lineages during this period. Clade 20C became the most prevalent among sequenced cases and was replaced by other strains in fall 2020. Bayesian phylogeographic reconstructions suggested 42 independent introductions into Finland during spring 2020, mainly from Italy, Austria, and Spain, which might have been the source for a third of cases. The investigations of the original introductions of SARS-CoV-2 to Finland during the early stages of the pandemic and of the subsequent lineage dynamics could be utilized to assess the role of transboundary movements and effects of early intervention and public health measures.
Alkuperäiskielienglanti
LehtiResearch Square
ISSN2693-5015
DOI - pysyväislinkit
TilaValmisteltavana - 28 heinäkuuta 2021
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