In our view, Allan and Arroll (1) misrepresent the findings of our Cochrane review on vitamin C and colds (2). They state that "vitamin C may provide some benefit in people under physical stress". From 5 RCTs with participants under heavy short-term physical stress, we calculated that vitamin C reduced common cold incidence by 52%, which is a substantial effect. Thus, people who often catch a cold after heavy exercise should be encouraged to test whether vitamin C is useful for them (2).
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