Mouse Behavioural Phenotyping Facility

Utrustning/facilitet: Utrustning

  • Plats

    Mustialankatu 1G

    F-building

    Helsinki

    Finland

Utrustningsinformation

Text

Mouse genetic models play a key role in the investigation of molecular pathways underlying normal biological functions or pathological states. The models require extensive analysis at various levels of complexity. Behavioural testing is an important approach in comprehensive studies aimed at understanding psychiatric and neurological diseases. The analysis of mouse behaviour in laboratory conditions is undergoing a rapid evolution, and a growing need exists for expertise in this field. Behavioural core unit is a state-of-the-art laboratory providing collaboration-based service for researchers interested in behavioural or neuropharmacological examination of the mice. Unit provides professional assistance in design and implementation of behavioural experiments, as well as in data analysis and interpretation.

Forskningsinfrastrukturens typ

  • !!Equipment
  • !!Service

Vetenskapsgrenar

  • 3112 Neurovetenskaper

HU forskningsinfrastruktur klassificering

  • Central serviceenhet

Forskningsresultat

Trim37-deficient mice recapitulate several features of the multi-organ disorder Mulibrey nanism

Kettunen, K. M., Karikoski, R., Hamalainen, R. H., Toivonen, T. T., Antonenkov, V. D., Kulesskaya, N., Voikar, V., Holtta-Vuori, M., Ikonen, E., Sainio, K., Jalanko, A., Karlberg, S., Karlberg, N., Lipsanen-Nyman, M., Toppari, J., Jauhiainen, M., Hiltunen, J. K., Jalanko, H. & Lehesjoki, A-E., 15 maj 2016, I : Biology open. 5, 5, s. 584-595 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Differential expression of brain immune genes and schizophrenia-related behavior in C57BL/6N and DBA/2J female mice

Ma, L., Kulesskaya, N., Voikar, V. & Tian, L., mar 2015, I : Psychiatry Research. 226, 1, s. 211-216 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

GDNF is not required for catecholaminergic neuron survival in vivo

Kopra, J., Vilenius, C., Grealish, S., Härma, M-A., Varendi, K., Lindholm, J., Castrén, E., Voikar, V., Björklund, A., Piepponen, T. P., Saarma, M. & Andressoo, J-O., mar 2015, I : Nature Neuroscience. 18, 3, s. 319-322 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review