Avdelningen för farmaceutiska biovetenskaper

  • Finland

Publikationer 1986 2020

2020
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Endothermic and Exothermic Energy Transfer Made Equally Efficient for Triplet-Triplet Annihilation Upconversion

Isokuortti, J., Allu, S. R., Efimov, A., Vuorimaa-Laukkanen, E., Tkachenko, N. V., Vinogradov, S. A., Laaksonen, T. & Durandin, N. A., 2 jan 2020, I : Journal of Physical Chemistry Letters. 11, 1, s. 318-324 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Linking volatile and non-volatile compounds to sensory profiles and consumer liking of wild edible Nordic mushrooms

Aisala, H., Manninen, H., Laaksonen, T., Linderborg, K. M., Myoda, T., Hopia, A. & Sandell, M., 30 jan 2020, I : Food Chemistry. 304, 9 s., 125403.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Modeling membrane proteins: The importance of cysteine amino-acids

Grazhdankin, E., Stepniewski, M. & Xhaard, H., 1 jan 2020, I : Journal of Structural Biology. 209, 1, 9 s., 107400.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2019

Analysis of Spanish Radiometric Networks with the Novel Bias-Based Quality Control (BQC) Method

Urraca, R., Antonanzas, J., Sanz-Garcia, A. & Javier Martinez-de-Pison, F., 1 jun 2019, I : Sensors. 19, 11, 17 s., 2483.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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A nebulin super-repeat panel reveals stronger actin binding toward the ends of the super-repeat region

Laitila, J., Lehtonen, J., Lehtokari, V-L., Sagath, L., Wallgren-Pettersson, C., Grönholm, M. & Pelin, K., jan 2019, I : Muscle & Nerve. 59, 1, s. 116-121 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

An ethnobotanical survey and antifungal activity of Piper guineense used for the treatment of fungal infections in West-African traditional medicine

Mgbeahuruike, E. E., Holm, Y., Vuorela, H., Amandikwa, C. & Fyhrquist, P., 30 jan 2019, I : Journal of Ethnopharmacology. 229, s. 157-166 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

An optimised series of substituted N-phenylpyrrolamides as DNA gyrase B inhibitors

Benetto Tiz, D., Skok, Ž., Durcik, M., Tomašič, T., Peterlin Mašič, L., Ilaš, J., Draskovits, G., Révész, T., Nyerges, Á., Pál, C., Cruz, C. D., Tammela, P. S. M., Žigon, D., Kikelj, D. & Zidar, N., 1 apr 2019, I : European Journal of Medicinal Chemistry. 167, s. 269-290 22 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Antibacterial and antioxidative properties of different parts of garden rhubarb, blackcurrant, chokeberry and blue honeysuckle

Raudsepp, P., Koskar, J., Anton, D., Meremäe, K., Kapp, K., Laurson, P., Bleive, U., Kaldmäe, H., Roasto, M. & Püssa, T., 30 mar 2019, I : Journal of the Science of Food and Agriculture. 99, 5, s. 2311-2320 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Antimicrobial and Synergistic Effects of Commercial Piperine and Piperlongumine in Combination with Conventional Antimicrobials

Mgbeahuruike, E. E., Stålnacke, M., Vuorela, H. & Holm, Y., jun 2019, I : Antibiotics. 8, 2, 12 s., 55.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Antimicrobial Colloidal Silver-Lignin Particles via Ion- and Solvent Exchange

Sakari Lintinen, K., Luiro, S., Figueiredo, P., Sakarinen, E., Mousavi, Z., Seitsonen, J., N. S. Rivière, G., Mattinen, U., Niemelä, M., Tammela, P., Österberg, M., Johansson, L-S., Bobacka, J., Santos, H. A. & A. Kostiainen, M., 16 sep 2019, I : ACS Sustainable Chemistry & Engineering. 7, 18, s. 15297-15303 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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A potent partial agonist of PKC orients in membranes like the biological activator diacylglycerol

Lautala, S., Koivuniemi, A., Kulig, W., Rog, T., Talman, V., Tuominen, R. & Bunker, A., jul 2019, I : European Biophysics Journal. 48, s. S122-S122 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

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Azithromycin-liposomes as a novel approach for localized therapy of cervicovaginal bacterial infections

Vanic, Z., Rukavina, Z., Manner, S., Fallarero, A., Uzelac, L., Kralj, M., Klaric, D. A., Bogdanov, A., Raffai, T., Virok, D. P., Filipovic-Grcic, J. & Skalko-Basnet, N., 2019, I : International Journal of Nanomedicine. 14, s. 5957-5976 20 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Azulene-based compounds targeting orexin receptors

Leino, T., Turku, A., Yli-Kauhaluoma, J., Kukkonen, J., Xhaard, H. & Wallen, E., 31 mar 2019, I : Abstracts of papers of the American Chemical Society . 257, 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Biohybrid Cloaked Nanovaccines for Cancer Immunotherapy

Fontana, F., 14 jun 2019, Helsinki: Helsinki University Printing House. 78 s.

Forskningsoutput: AvhandlingDoktorsavhandling

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Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor

Fontana, F., Fusciello, M., Groeneveldt, C., Capasso, C., Chiaro, J., Feola, S., Liu, Z., Mäkilä, E., Salonen, J., Hirvonen, J., Cerullo, V. & Santos, H. A., jun 2019, I : ACS Nano. 13, 6, s. 6477-6490 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Characterization of artificially re-pigmented ARPE-19 retinal pigment epithelial cell model

Hellinen, L., Hagström, M., Knuutila, H., Ruponen, M., Urtti, A. & Reinisalo, M., 24 sep 2019, I : Scientific Reports. 9, 10 s., 13761.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Characterization of CDNF-Secreting ARPE-19 Cell Clones for Encapsulated Cell Therapy

Galli, E., Lindholm, P., Kontturi, L-S., Saarma, M., Urtti, A. & Yliperttula, M., apr 2019, I : Cell Transplantation. 28, 4, s. 413-424 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Chemical characteristics and stability of eucalyptus kraft pulps bleached with tertiary amine catalyzed hypochlorous acid

Afsahi, G., Rojalin, T. & Vuorinen, T., feb 2019, I : Cellulose. 26, 3, s. 2047-2054 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Chondrogenic differentiation of human bone marrow-derived mesenchymal stromal cells in a three-dimensional environment

Salonius, E., Kontturi, L., Laitinen, A., Haaparanta, A-M., Korhonen, M., Nystedt, J., Kiviranta, I. & Muhonen, V., 25 sep 2019, I : Journal of Cellular Physiology. 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Clinical Study of Nanofibrillar Cellulose Hydrogel Dressing for Skin Graft Donor Site Treatment

Koivuniemi, R., Hakkarainen, T., Kiiskinen, J., Kosonen, M., Vuola, J., Valtonen, J., Luukko, K., Kavola, H. & Yliperttula, M., 4 jun 2019, I : Advances in wound care. 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Combination effects of essential oils with antimicrobials

Stalnacke, M., Mgbeahuruike, E. & Holm, Y., dec 2019, I : Planta Medica. 85, 18, s. 1523-1523 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

Clayton, A., Boilard, E., Buzas, E. I., Cheng, L., Falcón-Perez, J. M., Gardiner, C., Gustafson, D., Gualerzi, A., Hendrix, A., Hoffman, A., Jones, J., Lässer, C., Lawson, C., Lenassi, M., Nazarenko, I., O’Driscoll, L., Pink, R., Siljander, P. R-M., Soekmadji, C., Wauben, M. & 4 andra, Welsh, J. A., Witwer, K., Zheng, L. & Nieuwland, R., 1 dec 2019, I : Journal of Extracellular Vesicles. 8, 1, 5 s., 1647027.

Forskningsoutput: TidskriftsbidragArtikelVetenskaplig

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Design, Synthesis and Biological Evaluation of Novel DNA Gyrase Inhibitors and their Siderophore Mimic Conjugates

Lamut, A., Cruz, C. D., Skok, Ž., Barančoková, M., Zidar, N., Zega, A., Peterlin Mašič, L., Ilaš, J., Tammela, P., Kikelj, D. & Tomašič, T., 20 dec 2019, (!!Accepted/In press) I : Bioorganic Chemistry.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Design and evaluation of a multiplexed angular-scanning surface plasmon resonance system employing line-laser optics and CCD detection in combination with multi-ligand sensor chips

Lakayan, D., Tuppurainen, J., Suutari, T. E., van Iperen, D. J., Somsen, G. W. & Kool, J., 1 mar 2019, I : Sensors and Actuators B: Chemical. 282, s. 243-250 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties

Subrizi, A., del Amo, E. M., Korzhikov-Vlakh, V., Tennikova, T., Ruponen, M. & Urtti, A., aug 2019, I : Drug Discovery Today. 24, 8, s. 1446-1457 12 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Determinants of Orexin Receptor Binding and Activation—A Molecular Dynamics Study

Karhu, L., Magarkar, A., Bunker, A. & Xhaard, H., 28 mar 2019, I : Journal of Physical Chemistry B. 123, 12, s. 2609-2622 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Distribution of Small Molecular Weight Drugs into the Porcine Lens: Studies on Imaging Mass Spectrometry, Partition Coefficients, and Implications in Ocular Pharmacokinetics

Heilkkinen, E. M., Auriola, S., Ranta, V-P., Demarais, N. J., Grey, A. C., del Amo, E. M., Toropainen, E., Vellonen, K-S., Urtti, A. & Ruponen, M., sep 2019, I : Molecular Pharmaceutics. 16, 9, s. 3968-3976 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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DPD-inspired discovery of novel LsrK kinase inhibitors: an opportunity to fight antimicrobial resistance

Stotani, S., Gatta, V., Medarametla, P., Padmanaban, M., Karawajzyk, A., Giordanetto, F., Tammela, P., Laitinen, T., Poso, A., Tzalis, D. & Collina, S., 14 mar 2019, I : Journal of Medicinal Chemistry. 62, 5, s. 2720-2737 18 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effects of nanofibrillated cellulose hydrogels on adipose tissue extract and hepatocellular carcinoma cell spheroids in freeze-drying

Auvinen, V-V., Merivaara, A., Kiiskinen, J., Paukkonen, H., Laurén, P., Hakkarainen, T., Koivuniemi, R., Sarkanen, R., Ylikomi, T., Laaksonen, T. & Yliperttula, M., 15 sep 2019, I : Cryobiology. 91, s. 137-145 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Efficient Fabrication of Polycaprolactone Scaffolds for Printing Hybrid Tissue-Engineered Constructs

Sodupe Ortega, E., Sanz-Garcia, A., Pernia-Espinoza, A. & Escobedo-Lucea, C., 2 feb 2019, I : Materials. 12, 4, 18 s., 613.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Efflux transport of nicotine, cotinine and trans-3 '-hydroxycotinine glucuronides by human hepatic transporters

Jarvinen, E., Sjöstedt, N., Koenderink, J. B., Kidron, H. & Finel, M., dec 2019, I : Basic & Clinical Pharmacology & Toxicology. 125, 6, s. 490-498 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Electrical synapses interconnecting axons revealed in the optic nerve head – a novel model of gap junctions’ involvement in optic nerve function

Smedowski, A., Akhtar, S., Liu, X., Pietrucha-Dutczak, M., Podracka, L., Toropainen, E., Alkanaan, A., Ruponen, M., Urtti, A., Varjosalo, M., Kaarniranta, K. & Lewin-Kowalik, J., 10 okt 2019, I : Acta Ophthalmologica. 0, 0

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Electron dispersive X-ray spectroscopy and degradation properties of hyaluronic acid decorated microparticles

Serri, C., Frigione, M., Ruponen, M., Urtti, A., Borzacchiello, A., Biondi, M., Itkonen, J. & Mayol, L., 1 sep 2019, I : Colloids and Surfaces B: Biointerfaces. 181, s. 896-901 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Enantiospecific pharmacogenomics of fluvastatin

Hirvensalo, P., Tornio, A., Neuvonen, M., Kiander, W., Kidron, H., Paile-Hyvärinen, M., Tapaninen, T., Backman, J. T. & Niemi, M., sep 2019, I : Clinical Pharmacology and Therapeutics. 106, 3, s. 668-680 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Endogenous, cholesterol-activated ATP-dependent transport in membrane vesicles from Spodoptera frugiperda cells

Sjöstedt, N., Salminen, T. A. & Kidron, H., 1 sep 2019, I : European Journal of Pharmaceutical Sciences. 137, 9 s., 104963.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Enhanced coordination of care to reduce medication risks in older home care clients in primary care: a randomized controlled trial

Toivo, T., Airaksinen, M., Dimitrow, M., Savela, E., Pelkonen, K., Kiuru, V., Suominen, T., Uunimäki, M., Kivelä, S-L., Leikola, S. & Puustinen, J., 27 nov 2019, I : BMC Geriatrics. 19, 1, 13 s., 332.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Equity and diversity in academic medicine: a perspective from the JCI editors

Resar, L. M. S., Jaffee, E. M., Armanios, M., Jackson, S., Azad, N. S., Horton, M. R., Kaplan, M. J., Laiho, M., Maus, M. V., Sumner, C. J., Wheelan, S. J. & Wills-Karp, M., 1 okt 2019, I : Journal of Clinical Investigation. 129, 10, s. 3974-3977 4 s.

Forskningsoutput: TidskriftsbidragLedareVetenskaplig

Establishment of an In Vitro-In Vivo Correlation for Melanin Binding and the Extension of the Ocular Half-Life of Small-Molecule Drugs

Jakubiak, P., Cantrill, C., Urtti, A. & Alvarez-Sanchez, R., dec 2019, I : Molecular Pharmaceutics. 16, 12, s. 4890-4901 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Evaluation of quorum sensing inhibitory activity of bis-primaquine derivatives

Pavić, K., Patel, J., Savijoki, K., Fallarero, A., Yli-Kauhaluoma, J., Rajić, Z. & Zorc, B., 4 apr 2019.

Forskningsoutput: KonferensbidragPoster

Exploring Light-Sensitive Nanocarriers for Simultaneous Triggered Antibiotic Release and Disruption of Biofilms Upon Generation of Laser-Induced Vapor Nanobubbles

Teirlinck, E., Barras, A., Liu, J., Fraire, J. C., Lajunen, T., Xiong, R., Forier, K., Li, C., Urtti, A., Boukherroub, R., Szunerits, S., De Smedt, S. C., Coenye, T. & Braeckmans, K., maj 2019, I : Pharmaceutics. 11, 5, 15 s., 201.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Exploring the mucoadhesive behavior of sucrose acetate isobutyrate: a novel excipient for oral delivery of biopharmaceuticals

Harloff-Helleberg, S., Fliervoet, L. A. L., Fano, M., Schmitt, M., Antopolski, M., Urtti, A. & Nielsen, H. M., 1 jan 2019, I : Drug Delivery. 26, 1, s. 532-541 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Extracellular vesicles enhance the targeted delivery of immunogenic oncolytic adenovirus and paclitaxel in immunocompetent mice

Garofalo, M., Villa, A., Rizzi, N., Kuryk, L., Rinner, B., Cerullo, V., Yliperttula, M., Mazzaferro, V. & Ciana, P., 28 jan 2019, I : Journal of Controlled Release. 294, s. 165-175 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review