• P.O. Box 56 (Viikinkaari 9), Biocenter 1

    00014 UNIVERSITY OF HELSINKI

    Finland

Organisationsprofil

Organisationsprofil

The Glycoscience group headed by Professor Jukka Finne is engaged with the biology of carbohydrates, the most abundant biological molecules of nature, involved in the biology of all living organisms. Glycans have received little attention due to lack of efficient tools to probe their complex structures and properties.

The group has focused on the study of two main topics of carbohydrate interactions: the role of polysialic acid, a developmentally regulated carbohydrate moiety of cell adhesion molecules originally discovered by us, in the childhood cancer neuroblastoma, as well as the role of cell surface carbohydrates in the adhesion of pathogenic bacteria to the cells of our body.

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Projekt 2013 2016

Cytotoxic constructs targeting polysialic acid

Lehti, T., Skog, M., Lilie, H., Nacher, J. & Finne, J.

Projekt: Forskningsprojekt

Role of polysialic acid in human neuroblastoma

Finne, J., Vettenranta, K., Sariola, H., Porkka, K. & Lehti, T.

Projekt: Forskningsprojekt

Towards picomolar inhibitors of bacterial adhesion

Finne, J., Haataja, S., Nilsson, U. & Pieters, R.

Projekt: Forskningsprojekt

Publikationer 1974 2018

Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering

Rasila, T. S., Pulkkinen, E., Kiljunen, S., Haapa-Paananen, S., Pajunen, M. I., Salminen, A., Paulin, L., Vihinen, M., Rice, P. A. & Savilahti, H., 18 maj 2018, I : Nucleic Acids Research. 46, 9, s. 4649-4661 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Rationally designed chemically modified glycodendrimer inhibits Streptococcus suis adhesin SadP at picomolar concentrations

Haataja, S., Verma, P., Fu, O., Papageorgiou, A. C., Pöysti, S., Pieters, R. J., Nilsson, U. J. & Finne, J., 2018, I : Chemistry: A European Journal. 24, 8, s. 1905-1912 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells

Lehti, T. A., Pajunen, M. I., Skog, M. S. & Finne, J., 4 dec 2017, I : Nature Communications. 8, 12 s., 1915.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O: 3 are mediated by derepression of the transcriptional regulator RovM

Leskinen, K., Pajunen, M. I., Varjosalo, M., Fernandez-Carrasco, H., Bengoechea, J. A. & Skurnik, M., mar 2017, I : Molecular Microbiology. 103, 6, s. 1065-1091 27 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång

Aktiviteter 1978 2020

Member of the Scientific Advisory Board of Sialoglyco 2020 Meeting, Gifu, Japan

Jukka Finne (Medlem av vetenskaplig kommitté)
2020

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Member of the Council of the Finnish Union of University Professors

Jukka Finne (Deltagare)
20192020

Aktivitet: Andra aktivitetstyperTyper av övriga aktiviteter - Övrigt

Societas Biophysica, Biochimica et Microbiologica Fenniae (Extern organisation)

Jukka Finne (Styrelsemedlem)
2019

Aktivitet: MedlemskapstyperMedlemskap eller annan role i inhemsk/internationell kommitté, råd, styrelse

Invited speaker at 25th International Symposium on Glycoconjugates, Milan, Italy

Jukka Finne (Talare: Presentation)
2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Member of the Board of the University Helsinki branch of the Finnish Union of University Professors

Jukka Finne (Deltagare)
2019

Aktivitet: Andra aktivitetstyperTyper av övriga aktiviteter - Övrigt

Press / media

Interviewed for an article in Acatiimi

Jukka Finne

01/01/2016

1 mediabidrag

Press/media: !!Press / Media

Interviewed for an article in Yliopisto-lehti

Jukka Finne

01/01/2015

1 mediabidrag

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Interviewed for an article in Teknia Journal

Jukka Finne

01/01/1995

1 mediabidrag

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Interviewed for local news program in radio

Jukka Finne

01/01/1989

1 mediabidrag

Press/media: !!Press / Media

Interviewed for local news program in radio

Jukka Finne

01/01/1988

1 mediabidrag

Press/media: !!Press / Media