Projekt per år
Organisationsprofil
Organisationsprofil
The Glycoscience group headed by Professor Jukka Finne is engaged with the biology of carbohydrates, the most abundant biological molecules of nature, involved in the biology of all living organisms. Glycans have received little attention due to lack of efficient tools to probe their complex structures and properties.
The group has focused on the study of two main topics of carbohydrate interactions: the role of polysialic acid, a developmentally regulated carbohydrate moiety of cell adhesion molecules originally discovered by us, in the childhood cancer neuroblastoma, as well as the role of cell surface carbohydrates in the adhesion of pathogenic bacteria to the cells of our body.
Internationellt och inhemskt samarbete
Publikationer och projekt inom de senaste fem åren.
Personer
Maria Pajunen
- Glycoscience Group
- Human Microbiome Research - universitetsforskare
Person: U3 Undervisnings- och forskningspersonal, HU
Projekt 2013 2016
Neural cell adhesion molecule and polysialic acid in clinical-grade human bone marrow-derived mesenchymal stromal cell
Skog, M., Pajunen, M., Anderson, H. & Colley, K.
Projekt: Forskningsprojekt
Regulation of polysialic acid expression
Pajunen, M., Anderson, H., Lehti, T., Skog, M., Schachner, M., Kallioniemi, O., Saarela, J. & Finne, J.
Projekt: Forskningsprojekt
Cytotoxic constructs targeting polysialic acid
Lehti, T., Skog, M., Lilie, H., Nacher, J. & Finne, J.
Projekt: Forskningsprojekt
Role of polysialic acid in human neuroblastoma
Finne, J., Vettenranta, K., Sariola, H., Porkka, K. & Lehti, T.
Projekt: Forskningsprojekt
Towards picomolar inhibitors of bacterial adhesion
Finne, J., Haataja, S., Nilsson, U. & Pieters, R.
Projekt: Forskningsprojekt
Publikationer 1974 2018
Mu transpososome activity-profiling yields hyperactive MuA variants for highly efficient genetic and genome engineering
Rasila, T. S., Pulkkinen, E., Kiljunen, S., Haapa-Paananen, S., Pajunen, M. I., Salminen, A., Paulin, L., Vihinen, M., Rice, P. A. & Savilahti, H., 18 maj 2018, I : Nucleic Acids Research. 46, 9, s. 4649-4661 12 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång
Fil
Rationally designed chemically modified glycodendrimer inhibits Streptococcus suis adhesin SadP at picomolar concentrations
Haataja, S., Verma, P., Fu, O., Papageorgiou, A. C., Pöysti, S., Pieters, R. J., Nilsson, U. J. & Finne, J., 2018, I : Chemistry: A European Journal. 24, 8, s. 1905-1912 8 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Internalization of a polysialic acid-binding Escherichia coli bacteriophage into eukaryotic neuroblastoma cells
Lehti, T. A., Pajunen, M. I., Skog, M. S. & Finne, J., 4 dec 2017, I : Nature Communications. 8, 12 s., 1915.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång
Fil
Phages crossing the border to eukaryotes: Is there a gateway for bacteriophages to get access to the interior of eukaryotic cells?
Lehti, T. A. & Finne, J., 4 dec 2017, I : Nature Microbiology.Forskningsoutput: Tidskriftsbidrag › Kommentar/debatt › Professionell
Several Hfq-dependent alterations in physiology of Yersinia enterocolitica O: 3 are mediated by derepression of the transcriptional regulator RovM
Leskinen, K., Pajunen, M. I., Varjosalo, M., Fernandez-Carrasco, H., Bengoechea, J. A. & Skurnik, M., mar 2017, I : Molecular Microbiology. 103, 6, s. 1065-1091 27 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgång
Aktiviteter 1978 2020
Member of the Scientific Advisory Board of Sialoglyco 2020 Meeting, Gifu, Japan
Jukka Finne (Medlem av vetenskaplig kommitté)2020
Aktivitet: Typer för deltagande i eller organisering av evenemang › Arrangemang av och deltagande i konferens/workshop/kurs/seminarium
Member of the Council of the Finnish Union of University Professors
Jukka Finne (Deltagare)2019 → 2020
Aktivitet: Andra aktivitetstyper › Typer av övriga aktiviteter - Övrigt
Societas Biophysica, Biochimica et Microbiologica Fenniae (Extern organisation)
Jukka Finne (Styrelsemedlem)2019
Aktivitet: Medlemskapstyper › Medlemskap eller annan role i inhemsk/internationell kommitté, råd, styrelse
Invited speaker at 25th International Symposium on Glycoconjugates, Milan, Italy
Jukka Finne (Talare: Presentation)2019
Aktivitet: Typer för deltagande i eller organisering av evenemang › Arrangemang av och deltagande i konferens/workshop/kurs/seminarium
Member of the Board of the University Helsinki branch of the Finnish Union of University Professors
Jukka Finne (Deltagare)2019
Aktivitet: Andra aktivitetstyper › Typer av övriga aktiviteter - Övrigt
Priser
Awarded as a member of the MembRec group in the International evaluation of research and doctoral training training of the University of Helsinki
Jukka Finne (!!Recipient), 2013
Pris: Pris och hedersbetygelser
Golden medal of the Federation of Finnish Learned Societies and Universities Finland UNIFI
Jukka Finne (!!Recipient), 2016
Pris: Pris och hedersbetygelser
Young Researcher's Prize of Duodecim (Finnish College of Physicians)
Jukka Finne (!!Recipient), 1985
Pris: Pris och hedersbetygelser