Helsinki Institute of Life Science HiLIFE

  • Finland

  • Finland

Publikationer 1966 2020

Blurring the germline: Genome editing and transgenerational epigenetic inheritance

Nordberg, A., Minssen, T., Feeney, O., Beriain, I. D. M., Galvagni, L. & Wartiovaara, K., jan 2020, I : Bioethics. 34, 1, s. 16-32 17 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Cost-effective survival prediction for patients with advanced prostate cancer using clinical trial and real-world hospital registry datasets

Murtojärvi, M., Halkola, A. S., Airola, A., Laajala, T. D., Mirtti, T., Aittokallio, T. & Pahikkala, T., jan 2020, I : International Journal of Medical Informatics. 133, 8 s., 104014.

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Cross-sectional associations between the diversity of sport activities and the type of low back pain in adulthood

Kaartinen, S., Aaltonen, S., Korhonen, T., Rottensteiner, M., Kujala, U. M. & Kaprio, J., 4 jan 2020, I : European Journal of Sport Science. 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Dereplication of natural products with antimicrobial and anticancer activity from Brazilian cyanobacteria.

Shishido, T. K., Vicentini Popin, R., Jokela, J., Wahlsten, M., Fiore, M. F., Fewer, D., Herfindal, L. & Sivonen, K., jan 2020, I : Toxins. 12, 12, 17 s., 2020, 12, 12.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Design, Synthesis and Characterization of a PEGylated Stanozolol for Potential Therapeutic Applications

Vergallo, C., Torrieri, G., Provenzani, R., Miettinen, S., Moslova, K., Varjosalo, M., Cristiano, M. C., Fresta, M., Celia, C., Santos, H. A., Cilurzo, F. & Di Marzio, L., 5 jan 2020, I : International Journal of Pharmaceutics. 573, 11 s., 118826.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Digital image analysis of multiplex fluorescence IHC in colorectal cancer recognizes the prognostic value of CDX2 and its negative correlation with SOX2

Lopes, N., Bergsland, C. H., Bjornslett, M., Pellinen, T., Svindland, A., Nesbakken, A., Almeida, R., Lothe, R. A., David, L. & Bruun, J., jan 2020, I : Laboratory Investigation. 100, 1, s. 120-134 15 s.

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Gelatin Templated Polypeptide Co-crosslinked Hydrogel for Bone Regeneration

Qiao, Y., Liu, X., Zhou, X., Zhang, H., Zhang, W., Xiao, W., Pan, G., Cui, W., Santos, H. A. & Shi, Q., 8 jan 2020, I : Advanced Healthcare Materials. 9, 1, 7 s., 1901239.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Haptoglobin Hp1 variant does not associate with small vessel disease

Lempiäinen, J. E., Ijäs, P., Niiranen, T. J., Kaste, M., Karhunen, P., Lindsberg, P., Erkinjuntti, T. J. & Melkas, S., 1 jan 2020, I : Brain Sciences. 2020 10, 18, 8 s., 10.3390/brainsci10010018.

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High-dimensional structure learning of binary pairwise Markov networks: A comparative numerical study

Pensar, J., Xu, Y., Puranen, S., Pesonen, M., Kabashima, Y. & Corander, J., jan 2020, I : Computational Statistics & Data Analysis. 141, s. 62-76 15 s.

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High-throughput retrotransposon-based genetic diversity of maize germplasm assessment and analysis

Ghonaim, M., Kalendar, R., Barakat, H., Elsherif, N., Ashry, N. & Schulman, A., 9 jan 2020, I : Molecular Biology Reports. 47, 2, s. 1-15

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Implant survival of constrained acetabular device in primary total hip arthroplasty based on data from the Finnish Arthroplasty Register

Karvonen, M., Laaksonen, I., Pulkkinen, P., Eskelinen, A., Haapakoski, J., Puhto, A-P., Kettunen, J., Manninen, M. & Mäkelä, K. T., jan 2020, I : Journal of Arthroplasty. 35, 1, s. 219-223 5 s.

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Life-long impairment of glucose homeostasis upon prenatal exposure to psychostimulants

Korchynska, S., Krassnitzer, M., Malenczyk, K., Prasad, R. B., Tretiakov, E. O., Rehman, S., Cinquina, V., Gernedl, V., Farlik, M., Petersen, J., Hannes, S., Schachenhofer, J., Reisinger, S. N., Zambon, A., Asplund, O., Artner, I., Keimpema, E., Lubec, G., Mulder, J., Bock, C. & 6 andra, Pollak, D. D., Romanov, R. A., Pifl, C., Groop, L., Hokfelt, T. G. M. & Harkany, T., 2 jan 2020, I : EMBO Journal. 39, 1, 19 s., 100882.

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Manuscript ANA-19-1498

Palotie, A., 6 jan 2020, I : Annals of Neurology. Issue 1/ 2020 / Volume 87

Forskningsoutput: TidskriftsbidragLitteraturöversiktVetenskapligPeer review

Microfluidics for Production of Particles: Mechanism, Methodology, and Applications

Liu, Z., Fontana, F., Python, A., Hirvonen, J. T. & Santos, H. A., 2020, I : Small. 24 s., 1904673.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Osteogenic Hydrogels: Gelatin Templated Polypeptide Co‐Cross‐Linked Hydrogel for Bone Regeneration (Adv. Healthcare Mater. 1/2020)

Qiao, Y., Liu, X., Zhou, X., Zhang, H., Zhang, W., Xiao, W., Pan, G., Cui, W., Santos, H. A. & Shi, Q., 8 jan 2020, I : Advanced Healthcare Materials. 9, 1, s. 2070001 1 s., 2070001.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Reactive oxygen species responsive nanoplatforms as smart drug delivery systems for gastrointestinal tract targeting

Bertoni, S., Machness, A., Tiboni, M., Bártolo, R. & Santos, H. A., 2020, I : Biopolymers. 14 s., 23336.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Regulation of INF2-mediated actin polymerization through site-specific lysine acetylation of actin itself

A, M., Fung, T. S., Francomacaro, L. M., Huynh, T., Kotila, T., Svindrych, Z. & Higgs, H. N., 7 jan 2020, I : Proceedings of the National Academy of Sciences of the United States of America. 117, 1

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Streptococcus halichoeri - Comparative Genomics of an emerging pathogen

Aaltonen, K., Kant, R., Eklund, M., Raunio-Saarnisto, M., Paulin, L., Vapalahti, O., Grönthal, T., Rantala, M. & Sironen, T., 14 jan 2020, (!!Accepted/In press) I : International Journal of Genomics.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Structural basis of SALM3 dimerization and synaptic adhesion complex formation with PTPσ

Karki, S., Shkumatov, A. V., Bae, S., Ko, J. & Kajander, T., 9 jan 2020, I : bioRxiv : the preprint server for biology .

Forskningsoutput: TidskriftsbidragAndra artiklarVetenskaplig

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The family-based assessment of HNF1A-MODY

Kettunen, J. L. T., Miettinen, P. J., Isomaa, B., Groop, L. & Tuomi, T., 2020.

Forskningsoutput: KonferensbidragKonferenspapper

2019

1-Hour Post-OGTT Glucose Improves the Early Prediction of Type 2 Diabetes by Clinical and Metabolic Markers

Peddinti, G., Bergman, M., Tuomi, T. & Groop, L., apr 2019, I : Journal of Clinical Endocrinology and Metabolism. 104, 4, s. 1131-1140 10 s.

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2018 William Allan Award Introduction: Eric S. Lander

Daly, M. J., 7 mar 2019, I : American Journal of Human Genetics. 104, 3, s. 373-374 2 s.

Forskningsoutput: TidskriftsbidragLedareVetenskaplig

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5-year versus risk-category-specific screening intervals for cardiovascular disease prevention: a cohort study

Lindbohm, J., Sipilä, P. N., Mars, N. J., Pentti, J., Ahmadi-Abhari, S., Brunner, E. J., Shipley, M. J., Singh-Manoux, A., Tabak, A. G. & Kivimäki, M., apr 2019, I : The Lancet Public Health. 4, 4, s. E189-E199 11 s.

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8-chloro-adenosine activity in FLT3-ITD acute myeloid leukemia

Buettner, R., Le Xuan Truong Nguyen, Kumar, B., Morales, C., Liu, C., Chen, L. S., Pemovska, T., Synold, T. W., Palmer, J., Thompson, R., Li, L., Dinh Hoa Hoang, Zhang, B., Ghoda, L., Kowolik, C., Kontro, M., Leitch, C., Wennerberg, K., Yu, X., Chen, C-C. & 5 andra, Horne, D., Gandhi, V., Pullarkat, V., Marcucci, G. & Rosen, S. T., sep 2019, I : Journal of Cellular Physiology. 234, 9, s. 16295-16303 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

A 2.8-Angstrom-Resolution Cryo-Electron Microscopy Structure of Human Parechovirus 3 in Complex with Fab from a Neutralizing Antibody

Domanska, A., Flatt, J. W., Jukonen, J., Geraets, J. & Butcher, S. J., feb 2019, I : Journal of Virology. 93, 4, 12 s., e01597-18.

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A beta2-Integrin/MRTF-A/SRF Pathway Regulates Dendritic Cell Gene Expression, Adhesion, and Traction Force Generation

Guenther, C., Faisal, I., Uotila, L., Llort Asens, M., Harjunpää, H., Savinko, T., Öhman, T., Yao, S., Moser, M., Morris, S. W., Tojkander, S. & Fagerholm, S., 28 maj 2019, I : Frontiers in Immunology. 10, 1138, 13 s., 1138.

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Abnormal behavior, striatal dopamine turnover and opioid peptide gene expression in histamine-deficient mice

Abdurakhmanova, S., Semenova, S., Piepponen, T. P. & Panula, P., nov 2019, I : Genes, Brain and Behavior. 18, 8, 12 s., 12595.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Accumulation of Progerin Affects the Symmetry of Cell Division and Is Associated with Impaired Wnt Signaling and the Mislocalization of Nuclear Envelope Proteins

Sola-Carvajal, A., Revechon, G., Helgadottir, H. T., Whisenant, D., Hagblom, R., Döhla, J., Katajisto, P., Brodin, D., Fagerstrom-Billai, F., Viceconte, N. & Eriksson, M., nov 2019, I : Journal of Investigative Dermatology. 139, 11, s. 2272-+ 21 s.

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Accuracy of self-reported anthropometric measures - Findings from the Finnish Twin Study

Tuomela, J., Kaprio, J., Sipilä, P. N., Silventoinen, K., Wang, X., Ollikainen, M. & Piirtola, M., 2019, I : Obesity Research & Clinical Practice. 13, 6, s. 522-528 7 s.

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A comprehensive evaluation of predictive performance of 33 species distribution models at species and community levels

Norberg, A., Abrego Antia, N., Blanchet, F. G., Adler, F. R., Anderson, B. J., Anttila, J., Araújo, M. B., Dallas, T. A., Dunson, D., Elith, J., Foster, S., Fox, R., Franklin, J., Godsoe, W., Guisan, A., O'Hara, B., Hill, N. A., Holt, R. D., Hui, F. K. C., Husby, M. & 15 andra, Kålås, J. A., Lehikoinen, A., Luoto, M., Mod, H. K., Newell, G., Renner, I., Roslin, T. V., Soininen, J., Thuiller, W., Vanhatalo, J. P., Warton, D., White, M., Zimmermann, N. E., Gravel, D. & Ovaskainen, O. T., aug 2019, I : Ecological Monographs. 89, 3, 24 s., 01370.

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A core mechanism for specifying root vascular patterning can replicate the anatomical variation seen in diverse plant species

Mellor, N., Vaughan-Hirsch, J., Kumpers, B. M. C., Help-Rinta-Rahko, H., Miyashima, S., Mahonen, A. P., Campilho, A., Kings, J. R. & Bishopp, A., mar 2019, I : Development. 146, 6, 10 s., 172411.

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Activation of P2X7 Receptors in Peritoneal and Meningeal Mast Cells Detected by Uptake of Organic Dyes: Possible Purinergic Triggers of Neuroinflammation in Meninges

Nurkhametova, D., Kudryavtsev, I., Guselnikova, V., Serebryakova, M., Giniatullina, R. R., Wojciechowski, S., Tore, F., Rizvanov, A., Koistinaho, J., Malm, T. & Giniatullin, R., 13 feb 2019, I : Frontiers in Cellular Neuroscience. 13

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Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine

Ribeiro, D. E., Casarotto, P. C., Júnior, A. S., Fernandes, G. G., Pinheiro, L. C., dos Santos, J. E. T., Júnior, H. Z., Guimarães, F. S., Joca, S. R. L. & Biojone, C., 13 apr 2019, I : Progress in Neuro-Psychopharmacology & Biological Psychiatry.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Additive multivariate Gaussian processes for joint species distribution modeling with heterogeneous data

Vanhatalo, J. P., Hartmann, M. & Veneranta, L., 2019, I : Bayesian analysis.

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Adenovirus Entry: From Infection to Immunity

Greber, U. F. & Flatt, J. W., 2019, ANNUAL REVIEW OF VIROLOGY, VOL 6, 2019. Enquist, L., DiMaio, D. & Demody, T. (red.). Annual Reviews, Vol. 6. s. 177-197 21 s. (Annual Review of Virology; vol. 6).

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

Adenovirus flow in host cell networks

Flatt, J. W. & Butcher, S. J., feb 2019, I : Open biology. 9, 2, 11 s., 190012.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

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A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle

Comai, G., Heude, E., Mella, S., Paisant, S., Pala, F., Gallardo, M., Langa, F., Kardon, G., Gopalakrishnan, S. & Tajbakhsh, S., 19 sep 2019, I : eLife. 8, 27 s., 47460.

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A Gaussian process model and Bayesian variable selection for mapping function-valued quantitative traits with incomplete phenotypic data

Vanhatalo, J., Li, Z. & Sillanpää, M. J., 1 okt 2019, I : Bioinformatics. 35, 19, s. 3684–3692 9 s.

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Aggressive behaviour in childhood and adolescence: the role of smoking during pregnancy, evidence from four twin cohorts in the EU-ACTION consortium

Malanchini, M., Smith-Woolley, E., Ayorech, Z., Rimfeld, K., Krapohl, E., Vuoksimaa, E., Korhonen, T., Bartels, M., van Beijsterveldt, T. C. E. M., Rose, R. J., Lundstrom, S., Anckarsater, H., Kaprio, J., Lichtenstein, P., Boomsma, D. I. & Plomin, R., mar 2019, I : Psychological Medicine. 49, 4, s. 646-654 9 s.

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A High Prevalence of Gastrointestinal Manifestations in Common Variable Immunodeficiency

Pikkarainen, S., Martelius, T., Ristimäki, A., Siitonen, S., Seppanen, M. R. J. & Färkkilä, M., apr 2019, I : American Journal of Gastroenterology. 114, 4, s. 648-655 8 s.

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Alcoholic liver disease - epidemiology, prognosis and risk factors

Sahlman, P., 2019, Helsinki: [P. Sahlman]. 57 s.

Forskningsoutput: AvhandlingDoktorsavhandling

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ALDH1A1-related stemness in high-grade serous ovarian cancer is a negative prognostic indicator but potentially targetable by EGFR/mTOR-PI3K/aurora kinase inhibitors

Kaipio, K., Chen, P., Roering, P., Huhtinen, K., Mikkonen, P., Östling, P., Lehtinen, L., Mansuri, N., Korpela, T., Potdar, S., Hynninen, J., Auranen, A., Grénman, S., Wennerberg, K., Hautaniemi, S. & Carpén, O., 3 dec 2019, I : Journal of Pathology. 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia

Batcha, A. M. N., Bamopoulos, S. A., Kerbs, P., Kumar, A., Jurinovic, V., Rothenberg-Thurley, M., Ksienzyk, B., Philippou-Massier, J., Krebs, S., Blum, H., Schneider, S., Konstandin, N., Bohlander, S. K., Heckman, C., Kontro, M., Hiddemann, W., Spiekermann, K., Braess, J., Metzeler, K. H., Greif, P. A. & 2 andra, Mansmann, U. & Herold, T., 13 aug 2019, I : Scientific Reports. 9, 11 s., 11796.

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