Anja Maria Söderlund-Venermo / Ansvarig forskare

  • Haartmaninkatu 3

    00290 Helsinki

    Finland

Organisationsprofil

Organisationsprofil

We assess the epidemiology, clinical impact and pathogenesis of human parvoviruses by development of an extensive repertoire of molecular and immunological diagnostic approaches and by characterization of virus-cell interactions.

Recent highlights:

- We showed that antibody EIA, mRNA RT-PCR or PCR of serum is needed for accurate diagnosis of acute HBoV1 infections, while the commonly used PCR of airway samples is insufficient.

- We showed that respiratory infections by HBoV1 are systemic, elicit immune responses, cause respiratory tract symptoms and otitis media, and affect almost all children before age 7.

- We showed that HBoV1 can persist in the upper airways for 6 months, cause life-threatening respiratory infections, can penetrate the blood-brain barrier causing encephalitis, and along with HBoV2-4, confuse serology by cross reactivity and an immunological phenomenon called “original antigenic sin”.

- We confirmed bufavirus to be a human virus and showed B-cell responses in humans.

- We found a striking difference in the global seroprevalence of BuV: 2-4% in Finland and the USA but 56-85% in Africa and the Middle East.

- We found a significant association of cutaneous T-cell lymphoma with detection of cutavirus DNA in skin biopsies.

 

Current team members: Elina Väisänen, Man Xu and Ushanandini Mohanraj

Recent short-term students: Yu Fu, Daranee Monthian, Maija Jokinen, and Michelle Ardales

Past PhD students: Kati Hokynar 2007, Laura Kakkola 2008, Anita Riipinen 2011, Päivi Norja 2012, Tingting Chen 2013, Kalle Kantola 2014, Reza Sadeghi 2014.

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer 2000 2019

ICTV Virus Taxonomy Profile: Parvoviridae

ICTV Report Consortium, Cotmore, S. F., Agbandje-McKenna, M., Canuti, M., Soderlund-Venermo, M. & Tattersall, P., mar 2019, I : Journal of General Virology. 100, 3, s. 367-368 2 s., 001212.

Forskningsoutput: TidskriftsbidragLedareVetenskaplig

Öppen tillgång
Fil

Pulmonary function and bronchial reactivity 4 years after the first virus-induced wheezing

Leino, A., Lukkarinen, M., Turunen, R., Vuorinen, T., Söderlund-Venermo, M., Vahlberg, T., Camargo, C. A., Bochkov, Y. A., Gern, J. E. & Jartti, T., mar 2019, I : Allergy : European journal of allergy and clinical immunology. 74, 3, s. 518-526 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Aktiviteter 1999 2018

Expert Review of Molecular Diagnostics (Tidskrift)

Maria Söderlund-Venermo (Referentgranskare)
2018

Aktivitet: Typer för peer review av output och redaktionsarbeteReferentgranskning av manuskript

Parvovirus Workshop

Maria Söderlund-Venermo (Medlem av vetenskaplig kommitté)
10 jun 201814 jun 2018

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Journal of General Virology (Tidskrift)

Maria Söderlund-Venermo (Referentgranskare)
2018

Aktivitet: Typer för peer review av output och redaktionsarbeteReferentgranskning av manuskript

Parvovirus Workshop

Maria Söderlund-Venermo (Talare: Inledningsanförande (keynote))
10 jun 201814 jun 2018

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

PhD Supervision

Maria Söderlund-Venermo (Handledare)
2018 → …

Aktivitet: ExaminationstyperHandledare eller bihandledare av doktorsavhandling

Priser

Award for outstanding review

Maria Söderlund-Venermo (!!Recipient), 2010

Pris: Pris och hedersbetygelser

Award for outstanding review

Maria Söderlund-Venermo (!!Recipient), 2008

Pris: Pris och hedersbetygelser