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2019

Associations between Microrna Expression, Disease Progression and Ex Vivo Drug Response in Multiple Myeloma

Kumari, R., Kumar, A., Parsons, A., Suvela, M., Lievonen, J., Silvennoinen, R., Anttila, P. & Heckman, C., 2019, I : Blood. 134, Supplement_1, 3069.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

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T Cell Landscape of Immune Aplastic Anemia Reveals a Convergent Antigen-Specific Signature

Huuhtanen, J., Lundgren, S., Keranen, M. A., Feng, X., Kerr, C. M., Jokinen, E., Heinonen, M., Savola, P., Kelkka, T., Ebeling, F., Ryland, G. L., Fox, L., Blombery, P., Lindberg, E. H., Young, N. S., Maciejewski, J. P., Lahdesmaki, H. & Mustjoki, S., 13 nov 2019, I : Blood. 134, Suppl. 1, s. 108-108 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2018

Combined Targeting of BET Family Proteins and BCL2 Is Synergistic in Acute Myeloid Leukemia Cells Overexpressing S100A8 and S100A9

Karjalainen, R., Liu, M., Kumar, A., Parsons, A., He, L., Malani, D. R., Kontro, M., Porkka, K. & Heckman, C. A., 2018, I : Blood. 132

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Genome-Scale CRISPR Screens Identify Essential Genes for Sensitivity to Natural Killer Cells in Hematological Malignancies

Dufva, O., Klievink, J., Saeed, K., Kankainen, M., Ilander, M., Hannunen, T., Lagstrom, S., Ellonen, P., Lee, D. A. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Multi-Parametric Single Cell Profiling Defines Distinct Drug Responses in Healthy Hematological Cell Lineages That Are Retained in Corresponding Malignant Cell Types

Majumder, MM., Leppä, A-M., Hellesøy, M., Dowling, P., Malyutina, A., Bazou, D., Andersson, E. I., Parsons, A., Tang, J., Kallioniemi, O-P., Mustjoki, S. M., O'Gorman, P., Wennerberg, J. K., Porkka, K. V. K., Gjertsen, B-T. & Heckman, C. A., 2018, I : Blood. 132

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Next-Generation Sequencing Reveals a T Cell Receptor Signature Characteristic of Patients with Aplastic Anemia

Lundgren, S., Huuhtanen, J., Keranen, M. A., Hirsch, C. M., Jokinen, E., Heinonen, M., Savola, P., Kelkka, T., Ebeling, F., Maciejewski, J. P., Hellstrom-Lindberg, E., Lahdesmaki, H. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Quantitative Multiplex Immunohistochemistry Identifies Immunosuppression in the AML Bone Marrow and NK-Cells As Prognostic Biomarker in Intermediate-Risk Patients

Bruck, O., Dufva, O., Blom, S., Turkki, R., Ilander, M., Siitonen, S. M., Kovanen, P., Pallaud, C., Ramos, P. M., Lahteenmaki, H., Valimaki, K., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Somatic Mutations in T Cells As Possible Regulators of Immunodeficiency

Savola, P., Martelius, T., Kankainen, M., Koski, Y., Eldfors, S., Huuhtanen, J., Kelkka, T., Lundgren, S., Ellonen, P., Kovanen, P., Kytola, S., Seppanen, M. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2017

CHRONIC MYELOID LEUKEMIA PATIENTS WERE NOT DIFFERENT IN MOLECULAR RELAPSE AFTER STOPPING IMATINIB IN MR4 WHETHER RESIDUAL DISEASE WAS DETECTED OR NOT - WHEN ADJUSTING FOR NUMBER OF CONTROL TRANSCRIPTS

Pfirrmann, M., Mahon, F-X., Guilhot, J., Richter, J., Almeida, A., Janssen, J. J., Mayer, J., Koskenvesa, P., Panayiotidis, P., Olsson-Stromberg, U., Berger, M. G., Diamond, J., Ehrencrona, H., Kairisto, V., Polakova, K. M., Mueller, M. C., Mustjoki, S., Hochhaus, A., Saussele, S. & Hjorth-Hansen, H., 26 jun 2017, I : Haematologica. 102, s. 153-153 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

CLINICAL AND IMMUNOLOGICAL EFFECTS OF NILOTINIB IN COMBINATION WITH PEGYLATED INTERFERON-A2B IN PATIENTS WITH SUBOPTIMAL MOLECULAR RESPONSE ON IMATINIB (NORDDUTCHCML009)

Geelen, I., Olsson-Stromberg, U., Mustjoki, S., Richter, J., Blijlevens, N., Smit, W., Gjertsen, B., Gedde-Dahl, T., Markevarn, B., Koppes, M., Westerweel, P., Janssen, J. & Hjorth-Hansen, H., 26 jun 2017, I : Haematologica. 102, s. 435-435 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Copanlisib (COP) in patients with relapsed or refractory indolent B-cell lymphoma: primary results of the pivotal Chronos-1 study

Dreyling, M., Santoro, A., Mollica, L., Leppa, S., Follows, G. A., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Stevens, D. A., Trevarthen, D., Giurescu, M., Kupit, L., Childs, B. H. & Zinzani, P. L., sep 2017, I : Oncology research and treatment. 40, s. 12-12 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Copanlisib in patients with relapsed or refractory follicular lymphoma.

Dreyling, M. H., Santoro, A., Leppa, S., Demeter, J., Follows, G., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provencio, M., Stevens, D. A., Trevarthen, D., Magagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., -Vargas, J. E. G., Childs, B. H. & Zinzani, P. L., 20 maj 2017, I : Journal of Clinical Oncology. 35, 5 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Copanlisib treatment in patients with relapsed or refractory indolent B-cell lymphoma: Subgroup analyses from the CHRONOS-1 study

Provencio Pulla, M., Santoro, A., Mollica, L., Leppa, S., Follows, G., Lenz, G., Kim, W. S., Nagler, A., Panayiotidis, P., Demeter, J., Ozcan, M., Kosinova, M., Bouabdallah, K., Morschhauser, F., Ishida, T., Huang, L., Garcia-Vargas, J., Childs, B. H., Zinzani, P. L. & Dreyling, M., sep 2017, I : Annals of Oncology. 28, 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

EFFICACY AND SAFETY OF COPANLISIB IN PATIENTS WITH RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: A SUBSET ANALYSIS OF THE CHRONOS-1 STUDY

Zinzani, P. L., Santoro, A., Leppa, S., Demeter, J., Follows, G. A., Lenz, G., Kim, W. S., Mollica, L., Nagler, A., Diong, C. P., Provenciio, M., Stevens, D. A., Trevarthen, D., Maagnoli, M., Cupit, L., Yin, S., Hiemeyer, F., Garcia-Vargas, J., Childs, B. H. & Dreyling, M., 26 jun 2017, I : Haematologica. 102, s. 314-315 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 dec 2017, I : Blood. 130, Suppl 1, s. Meeting Abstract: 2761 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 jun 2017, I : Haematologica. 102, s. 654-654 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

INCREASED INDOLEAMINE 2,3-DIOXYGENASE (IDO1) ACTIVITY IN EARLY CHRONIC PHASE CHRONIC MYELOGENOUS LEUKEMIA (CML-CP) IS REDUCED BY NILOTINIB THERAPY AND PREDICTS MOLECULAR RESPONSE

Sopper, S., Mustjoki, S., Gastl, G., Trajanoski, Z., Giles, F., Hochhaus, A., Janssen, J., Geisler, S., Fuchs, D. & Wolf, D., 26 jun 2017, I : Haematologica. 102, s. 232-233 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Indoleamine 2,3-Dioxygenase (Ido1) activity is increased in early chronic phase Chronic Myelogenous Leukemia (CML) and predicts molecular response to nilotinib therapy

Sopper, S., Mustjoki, S., Geisler, S., Fuchs, D., Hackl, H., Trajanoski, Z., Hochhaus, A. & Wolf, D., dec 2017, I : European Journal of Immunology. 47, s. 170-170 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 dec 2017, I : Blood. 130, 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

LOW IL-2 CONCENTRATION FAVORS GENERATION OF EARLY MEMORY T CELLS OVER TERMINAL EEFECTORS DURING CAR T-CELL EXPANSION

Luostarinen, A., Kaartinen, T., Maliniernii, P., Keto, J., Arvas, M., Belt, H., Koponen, J., Loskog, A., Mustjoki, S., Porkka, K., Yla-Herttuala, S. & Korhonen, M., maj 2017, I : Cytotherapy. 19, 5, s. S8-S8 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

TELOMERE SHORTENING IN CD34+38-BCR-ABL POSITIVE BONE MARROW CELLS FROM NEWLY DIAGNOSED PATIENTS WITH CML CORRELATES WITH THE CLONE SIZE OF THE LEUKEMIC STEM CELL COMPARTMENT

Bouillon, A. -S., Ferreira, M. V., Awad, S. A., Richter, J., Hjorth-Hansen, H., Hummel, S., Schemionek, M., Mustjoki, S., Beier, F. & Bruemmendorf, T. H., 26 jun 2017, I : Haematologica. 102, s. 231-232 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2014

Somatic Mutations in E3 Ubiquitin Ligase Deltex 1 Are Associated with Survival in Diffuse Large B-Cell Lymphoma

Taskinen, M., Meriranta, L., Pasanen, A., Louhimo, R., Cervera, A., Karjalainen-Lindsberg, M-L., Holte, H., Delabie, J., Lehtonen, R., Hautaniemi, S. & Leppa, S., 6 dec 2014, I : Blood. 124, 21, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review