II kirurgian klinikka

  • Finland

Publikationer

2020

Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas

Heby, M., Karnevi, E., Elebro, J., Nodin, B., Eberhard, J., Saukkonen, K., Hagström, J., Mustonen, H., Seppänen, H., Haglund, C., Jirstrom, K. & Larsson, A. H., 25 jun 2020, I : Scientific Reports. 10, 1, 10 s., 10373.

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Association between chronic pancreatitis and pancreatic cancer: A 10-year retrospective study of endoscopically treated and surgical patients

Korpela, T., Udd, M., Mustonen, H., Ristimäki, A., Haglund, C., Seppänen, H. & Kylänpää, L., 1 sep 2020, I : International Journal of Cancer. 147, 5, s. 1450-1460 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer

Gunnarsson, U., Strigård, K., Edin, S., Gkekas, I., Mustonen, H., Kaprio, T., Böckelman, C., Hagström, J., Palmqvist, R. & Haglund, C., 21 apr 2020, I : Journal of Translational Medicine. 18, 1, 8 s., 178.

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Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

German HNPCC Consortium, Dutch Lynch Syndrome Collaborative, Finnish Lynch Syndrome Registry, Engel, C., Ahadova, A., Seppälä, T. T., Lepistö, A., Renkonen-Sinisalo, L. & Vasen, H. F., apr 2020, I : Gastroenterology. 158, 5, s. 1326-1333 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Axillary nodal metastatic burden in patients with breast cancer with clinically positive axillary nodes

Niinikoski, L., Hukkinen, K., Leidenius, M. H. K., Heikkilä, P., Mattson, J. & Meretoja, T. J., 3 jun 2020, I : British Journal of Surgery. 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Benign biliary strictures treated with biodegradable stents in patients with surgically altered anatomy using double balloon enteroscopy

Lindström, O., Udd, M., Rainio, M., Nuutinen, H., Jokelainen, K. & Kylänpää, L., 11 aug 2020, I : Scandinavian Journal of Gastroenterology. 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Bile Reflux is a Common Finding in the Gastric Pouch After One Anastomosis Gastric Bypass

Saarinen, T., Pietiläinen, K. H., Loimaala, A., Ihalainen, T., Sammalkorpi, H., Penttilä, A. & Juuti, A., mar 2020, I : Obesity Surgery. 30, 3, s. 875-881 7 s.

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Biomarkers in pulmonary carcinoid tumors

Vesterinen, T., 2020, Helsinki: University of Helsinki. 93 s.

Forskningsoutput: AvhandlingDoktorsavhandlingSamling av artiklar

Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

The CAPP2 Investigators, Burn, J., Sheth, H., Elliott, F., Mecklin, J-P., Seppälä, T. T., Pylvänäinen, K. & Bishop, D. T., 13 jun 2020, I : Lancet. 395, 10240, s. 1855-1863 9 s.

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Dominguez-Valentin, M., Sampson, J. R., Seppälä, T. T., Ten Broeke, S. W., Plazzer, J-P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos Tot Nederveen Cappel, W. H., Sijmons, R. H. & 68 andra, Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Köstner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Knebel Doeberitz, M. V., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvänäinen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sánchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rødland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Möslein, G., Mecklin, J-P., Nielsen, M. & Møller, P., jan 2020, I : Genetics In medicine. 22, 1, s. 15-25 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Cell-in-cell phenomenon associates with aggressive characteristics and cancer-related mortality in early oral tongue cancer

Almangush, A., Mäkitie, A. A., Hagström, J., Haglund, C., Kowalski, L. P., Nieminen, P., Coletta, R. D., Salo, T. & Leivo, I., 3 sep 2020, I : BMC Cancer. 20, 1, 7 s., 843.

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Chronic use of statins and acetylsalicylic acid and incidence of post-endoscopic retrograde cholangiopancreatography acute pancreatitis: A multicenter, prospective, cohort study

Cardenas-Jaen, K., Archibugi, L., Poropat, G., Korpela, T., Maisonneuve, P., Aparicio, J. R., Udd, M., Stimac, D., Arcidiacono, P. G., De Pretis, N., Valente, R., Di Giulio, E., Casellas, J. A., Kylanpaa, L., Hauser, G., Mariani, A., Gabbrielli, A., Lohr, M., Vanella, G., Rainio, M. & 5 andra, Brozzi, L., Arnelo, U., Fagerstrom, N., Capurso, G. & de-Madaria, E., 28 sep 2020, I : Digestive Endoscopy. 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Classification, Severity Assessment, and Prevention of Recurrences in Acute Pancreatitis

Seppänen, H. & Puolakkainen, P., mar 2020, I : Scandinavian Journal of Surgery. 109, 1, s. 53-58 6 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

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Clinical management of 52 consecutive retro-rectal tumours treated at a tertiary referral centre

Carpelan-Holmström, M., Koskenvuo, L., Haapamäki, C. & Renkonen-Sinisalo, L., 18 maj 2020, I : Colorectal Disease. 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Colonic Adenocarcinomas Harboring NTRK Fusion Genes A Clinicopathologic and Molecular Genetic Study of 16 Cases and Review of the Literature

Lasota, J., Chlopek, M., Lamoureux, J., Christiansen, J., Kowalik, A., Wasag, B., Felisiak-Golabek, A., Agaimy, A., Biernat, W., Canzonieri, V., Centonze, G., Chmielik, E., Daum, O., Dubova, M., Dziuba, I., Goertz, S., Gozdz, S., Guttmejer-Nasierowska, A., Haglund, C., Halon, A. & 22 andra, Hartmann, A., Inaguma, S., Izycka-Swieszewska, E., Kaczorowski, M., Kita, P., Kolos, M., Kopczynski, J., Michal, M., Milione, M., Okon, K., Peksa, R., Pyzlak, M., Ristimäki, A., Rys, J., Szostak, B., Szpor, J., Szumilo, J., Teresinski, L., Waloszczyk, P., Wejman, J., Wesolowski, W. & Miettinen, M., feb 2020, I : American Journal of Surgical Pathology. 44, 2, s. 162-173 12 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Comment on: Evaluation of appendicitis risk prediction models in adults with suspected appendicitis

Mentula, P., Sammalkorpi, H. & Leppäniemi, A., jun 2020, I : British Journal of Surgery. 107, 7, s. E205-E205 1 s.

Forskningsoutput: TidskriftsbidragBrevVetenskaplig

Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients

Dickinson, A., Saraswat, M., Syrjänen, S., Tohmola, T., Silén, R., Randén-Brady, R., Carpén, T., Hagström, J., Haglund, C., Mattila, P., Mäkitie, A., Joenväärä, S. & Silén, S., 15 jun 2020, I : PLoS One. 15, 6, 13 s., 0233974.

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Comparison of operative link for gastritis assessment, operative link on gastric intestinal metaplasia assessment, and TAIM stagings among men with atrophic gastritis

Nieminen, A. A., Kontto, J., Puolakkainen, P., Virtamo, J. & Kokkola, A., 28 jun 2020, I : World Journal of Gastroenterology. 26, 24, s. 3447-3457 11 s.

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Comparison of supervised machine learning classification techniques in prediction of locoregional recurrences in early oral tongue cancer

Alabi, R. O., Elmusrati, M., Sawazaki-Calone, I., Kowalski, L. P., Haglund, C., Coletta, R. D., Mäkitie, A. A., Salo, T., Almangush, A. & Leivo, I., apr 2020, I : International Journal of Medical Informatics. 136, 8 s., 104068.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Diagnosis and treatment of acute appendicitis: 2020 update of the WSES Jerusalem guidelines

Di Saverio, S., Podda, M., De Simone, B., Ceresoli, M., Augustin, G., Gori, A., Boermeester, M., Sartelli, M., Coccolini, F., Tarasconi, A., Angelis, N. D., Weber, D. G., Tolonen, M., Birindelli, A., Biffl, W., Moore, E. E., Kelly, M., Soreide, K., Kashuk, J., Ten Broek, R. & 40 andra, Gomes, C. A., Sugrue, M., Davies, R. J., Damaskos, D., Leppäniemi, A., Kirkpatrick, A., Peitzman, A. B., Fraga, G. P., Maier, R. V., Coimbra, R., Chiarugi, M., Sganga, G., Pisanu, A., Angelis, G. L. D., Tan, E., Van Goor, H., Pata, F., Di Carlo, I., Chiara, O., Litvin, A., Campanile, F. C., Sakakushev, B., Tomadze, G., Demetrashvili, Z., Latifi, R., Abu-Zidan, F., Romeo, O., Segovia-Lohse, H., Baiocchi, G., Costa, D., Rizoli, S., Balogh, Z. J., Bendinelli, C., Scalea, T., Ivatury, R., Velmahos, G., Andersson, R., Kluger, Y., Ansaloni, L. & Catena, F., 15 apr 2020, I : World journal of emergency surgery. 15, 1, 42 s., 27.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

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Diclofenac does not reduce the risk of acute pancreatitis in patients with primary sclerosing cholangitis after endoscopic retrograde cholangiography

Koskensalo, V., Tenca, A., Udd, M., Lindström, O., Rainio, M., Jokelainen, K., Kylänpää, L. & Färkkilä, M., maj 2020, I : United european gastroenterology journal. 8, 4, s. 462-471 10 s.

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Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers

Blatter, R., Tschupp, B., Aretz, S., Bernstein, I., Colas, C., Evans, D. G., Genuardi, M., Hes, F. J., Hueneburg, R., Jarvinen, H., Lalloo, F., Moeslein, G., Renkonen-Sinisalo, L., Resta, N., Spier, I., Varvara, D., Vasen, H., Latchford, A. R. & Heinimann, K., 13 maj 2020, I : Genetics In medicine. 9 s.

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Doxapram as an additive to propofol sedation for endoscopic retrograde cholangiopancreatography: a placebo-controlled, randomized, double-blinded study

Jokelainen, J., Belozerskikh, A., Mustonen, H., Udd, M., Kylänpää, L., Lindström, O., Mazanikov, M. & Pöyhiä, R., 28 jan 2020, I : Surgical Endoscopy. 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Dysplasia in the mucosal biopsy specimen is still a warning sign of cancer in ulcerative colitis

Karjalainen, E. K., Renkonen-Sinisalo, L. & Lepistö, A. H., 14 jul 2020, I : Scandinavian Journal of Gastroenterology. 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effect And Predictive Value Of Routine Preoperative Laboratory Testing For Endoscopic Retrograde Cholangiopancreatography

Jokelainen, J., Ismail, S., Kylänpää, L., Udd, M., Mustonen, H., Lindström, O. & Pöyhiä, R., jun 2020, I : Scandinavian Journal of Surgery. 109, 2, s. 115-120 6 s.

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Ei-alkoholiperäinen rasvamaksatauti (NAFLD)

Yki-Järvinen, H., Arkkila, P., Eskelinen, S., Juuti, A., Lapatto, R., Lempiäinen, A., Mervaala, E., Schwab Nikkola, A. & Winterfeld, U., 2020, I : Duodecim. 136, 4, s. 403-405 3 s.

Forskningsoutput: TidskriftsbidragArtikelProfessionell

Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma

Kylmä, A. K., Tolvanen, T. A., Carpén, T., Haglund, C., Mäkitie, A., Mattila, P. S., Grenman, R., Jouhi, L., Sorsa, T., Lehtonen, S. & Hagström, J., jun 2020, I : Experimental and Molecular Pathology. 114, 9 s., 104435.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Entero-atmospheric fistula migration: a new management alternative for complex septic open abdomen

Pereira, B. M., Duchesne, J. C., Concon-Filho, A. & Leppäniemi, A., 2020, I : Anaesthesiology Intensive Therapy. 52, 1, s. 56-62 7 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Epstein-Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact

Carpen, T., Syrjänen, S., Jouhi, L., Randen-Brady, R., Haglund, C., Mäkitie, A., Mattila, P. S. & Hagström, J., aug 2020, I : Cancer Immunology, Immunotherapy. 69, 8, s. 1615-1626 12 s.

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Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment

European-African, van Roessel, S., van Veldhuisen, E., Klompmaker, S., Tarvainen, T. & Besselink, M. G., 10 sep 2020, I : JAMA Oncology. 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Evaluation of prognosis and treatment response in colorectal cancer with focus on biomarkers

Hermunen, K., 2020, Helsinki: [K. Hermunen]. 114 s.

Forskningsoutput: AvhandlingDoktorsavhandlingSamling av artiklar

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Executive summary: WSES Guidelines for the management of severe acute pancreatitis

Leppäniemi, A., Tolonen, M., Tarasconi, A., Segovia-Lohse, H., Gamberini, E., Kirkpatrick, A. W., Ball, C. G., Parry, N., Sartelli, M., Wolbrink, D., van Goor, H., Baiocchi, G., Ansaloni, L., Biffl, W., Coccolini, F., Di Saverio, S., Kluger, Y., Moore, E. E. & Catena, F., jun 2020, I : Journal of trauma and acute care surgery. 88, 6, s. 888-890 3 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Factors associated with decision-making on prophylactic hysterectomy and attitudes towards gynecological surveillance among women with Lynch syndrome (LS): a descriptive study

Kalamo, M. H., Mäenpää, J. U., Seppälä, T. T., Mecklin, J. P., Huhtala, H., Sorvettula, K., Pylvänäinen, K. & Staff, S., apr 2020, I : Familial Cancer. 19, 2, s. 177-182 6 s.

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Familiaalinen adenomatoottinen polypoosi (FAP)

Koskenvuo, L., Pöyhönen, M. & Lepistö, A., 2020, I : Duodecim. 136, 1, s. 52-60 9 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Gut Microbiota and Host Gene Mutations in Colorectal Cancer Patients and Controls of Iranian and Finnish Origin

Sarhadi, V., Lahti, L., Saberi, F., Youssef, O., Kokkola, A., Karla, T., Tikkanen, M., Rautelin, H., Puolakkainen, P., Salehi, R. & Knuutila, S., mar 2020, I : Anticancer Research. 40, 3, s. 1325-1334 10 s.

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Hydroxysteroid 17-beta dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

Luukkonen, P. K., Tukiainen, T., Juuti, A., Sammalkorpi, H., Haridas, P. A. N., Niemelä, O., Arola, J., Orho-Melander, M., Hakkarainen, A., Kovanen, P. T., Dwivedi, O., Groop, L., Hodson, L., Gastaldelli, A., Hyötyläinen, T., Oresic, M. & Yki-Järvinen, H., 12 mar 2020, I : JCI INSIGHT. 5, 5, 12 s., 132158.

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Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population-based study

Väyrynen, V., Wirta, E. -V., Seppälä, T., Sihvo, E., Mecklin, J. -P., Vasala, K. & Kellokumpu, I., aug 2020, I : BMJ Open. 4, 4, s. 685-692 8 s.

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In HPV-negative oropharyngeal squamous cell carcinoma, elevated toll-like receptor 2 immunoexpression may increase the risk of disease-specific mortality

Kylmä, A. K., Jouhi, L., Mohamed, H., Randen-Brady, R., Mäkitie, A., Atula, T., Haglund, C., Sorsa, T. & Hagström, J., aug 2020, I : Oral Oncology. 107, 8 s., 104778.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Intraoperative surgical site infection control and prevention: a position paper and future addendum to WSES intra-abdominal infections guidelines

De Simone, B., Sartelli, M., Coccolini, F., Ball, C. G., Brambillasca, P., Chiarugi, M., Campanile, F. C., Nita, G., Corbella, D., Leppäniemi, A., Boschini, E., Moore, E. E., Biffl, W., Peitzmann, A., Kluger, Y., Sugrue, M., Fraga, G., Di Saverio, S., Weber, D., Sakakushev, B. & 10 andra, Chiara, O., Abu-Zidan, F. M., ten Broek, R., Kirkpatrick, A. W., Wani, I., Coimbra, R., Baiocchi, G. L., Kelly, M. D., Ansaloni, L. & Catena, F., 10 feb 2020, I : World journal of emergency surgery. 15, 1, 23 s., 10.

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Is preoperative bowel preparation always superfluous? reply

Koskenvuo, L. & Sallinen, V., 7 mar 2020, I : Lancet. 395, 10226, s. 782-782 1 s.

Forskningsoutput: TidskriftsbidragBrevVetenskaplig

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Iäkkään naisen vatsakipu

Pekkarinen, P. & Leppäniemi, A., 2020, I : Finnanest.. 53, 1, s. 54-57 4 s.

Forskningsoutput: TidskriftsbidragArtikelProfessionell

Kirurgia vaatii erityisjärjestelyjä COVID-19-pandemian aikana : välttämätön kirurginen toiminta on turvattava

Leppäniemi, A., Tolonen, M., Mentula, P. & Sallinen, V., 2020, I : Duodecim. 136, 12, s. 1377-1379 3 s.

Forskningsoutput: TidskriftsbidragLedareProfessionell

Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Holm, M., Saraswat, M., Joenväärä, S., Seppänen, H., Renkonen, R. & Haglund, C., 25 jun 2020, I : Tumor Biology. 42, 6, 10 s., 1010428320936410.

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