II kirurgian klinikka

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2020

Additive clinical impact of epidermal growth factor receptor and podocalyxin-like protein expression in pancreatic and periampullary adenocarcinomas

Heby, M., Karnevi, E., Elebro, J., Nodin, B., Eberhard, J., Saukkonen, K., Hagström, J., Mustonen, H., Seppänen, H., Haglund, C., Jirstrom, K. & Larsson, A. H., 25 jun 2020, I : Scientific Reports. 10, 1, 10 s., 10373.

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Association between chronic pancreatitis and pancreatic cancer: A 10-year retrospective study of endoscopically treated and surgical patients

Korpela, T., Udd, M., Mustonen, H., Ristimäki, A., Haglund, C., Seppänen, H. & Kylänpää, L., 1 sep 2020, I : International Journal of Cancer. 147, 5, s. 1450-1460 11 s.

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Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer

Gunnarsson, U., Strigård, K., Edin, S., Gkekas, I., Mustonen, H., Kaprio, T., Böckelman, C., Hagström, J., Palmqvist, R. & Haglund, C., 21 apr 2020, I : Journal of Translational Medicine. 18, 1, 8 s., 178.

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Associations of Pathogenic Variants in MLH1, MSH2, and MSH6 With Risk of Colorectal Adenomas and Tumors and With Somatic Mutations in Patients With Lynch Syndrome

German HNPCC Consortium, Dutch Lynch Syndrome Collaborative, Finnish Lynch Syndrome Registry, Engel, C., Ahadova, A., Seppälä, T. T., Lepistö, A., Renkonen-Sinisalo, L. & Vasen, H. F., apr 2020, I : Gastroenterology. 158, 5, s. 1326-1333 8 s.

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Axillary nodal metastatic burden in patients with breast cancer with clinically positive axillary nodes

Niinikoski, L., Hukkinen, K., Leidenius, M. H. K., Heikkilä, P., Mattson, J. & Meretoja, T. J., 3 jun 2020, I : British Journal of Surgery. 10 s.

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Benign biliary strictures treated with biodegradable stents in patients with surgically altered anatomy using double balloon enteroscopy

Lindström, O., Udd, M., Rainio, M., Nuutinen, H., Jokelainen, K. & Kylänpää, L., 11 aug 2020, I : Scandinavian Journal of Gastroenterology. 9 s.

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Bile Reflux is a Common Finding in the Gastric Pouch After One Anastomosis Gastric Bypass

Saarinen, T., Pietiläinen, K. H., Loimaala, A., Ihalainen, T., Sammalkorpi, H., Penttilä, A. & Juuti, A., mar 2020, I : Obesity Surgery. 30, 3, s. 875-881 7 s.

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Cancer prevention with aspirin in hereditary colorectal cancer (Lynch syndrome), 10-year follow-up and registry-based 20-year data in the CAPP2 study: a double-blind, randomised, placebo-controlled trial

The CAPP2 Investigators, Burn, J., Sheth, H., Elliott, F., Mecklin, J-P., Seppälä, T. T., Pylvänäinen, K. & Bishop, D. T., 13 jun 2020, I : Lancet. 395, 10240, s. 1855-1863 9 s.

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Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome Database

Dominguez-Valentin, M., Sampson, J. R., Seppälä, T. T., Ten Broeke, S. W., Plazzer, J-P., Nakken, S., Engel, C., Aretz, S., Jenkins, M. A., Sunde, L., Bernstein, I., Capella, G., Balaguer, F., Thomas, H., Evans, D. G., Burn, J., Greenblatt, M., Hovig, E., de Vos Tot Nederveen Cappel, W. H., Sijmons, R. H. & 68 andra, Bertario, L., Tibiletti, M. G., Cavestro, G. M., Lindblom, A., Della Valle, A., Lopez-Köstner, F., Gluck, N., Katz, L. H., Heinimann, K., Vaccaro, C. A., Büttner, R., Görgens, H., Holinski-Feder, E., Morak, M., Holzapfel, S., Hüneburg, R., Knebel Doeberitz, M. V., Loeffler, M., Rahner, N., Schackert, H. K., Steinke-Lange, V., Schmiegel, W., Vangala, D., Pylvänäinen, K., Renkonen-Sinisalo, L., Hopper, J. L., Win, A. K., Haile, R. W., Lindor, N. M., Gallinger, S., Le Marchand, L., Newcomb, P. A., Figueiredo, J. C., Thibodeau, S. N., Wadt, K., Therkildsen, C., Okkels, H., Ketabi, Z., Moreira, L., Sánchez, A., Serra-Burriel, M., Pineda, M., Navarro, M., Blanco, I., Green, K., Lalloo, F., Crosbie, E. J., Hill, J., Denton, O. G., Frayling, I. M., Rødland, E. A., Vasen, H., Mints, M., Neffa, F., Esperon, P., Alvarez, K., Kariv, R., Rosner, G., Pinero, T. A., Gonzalez, M. L., Kalfayan, P., Tjandra, D., Winship, I. M., Macrae, F., Möslein, G., Mecklin, J-P., Nielsen, M. & Møller, P., jan 2020, I : Genetics In medicine. 22, 1, s. 15-25 11 s.

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Cell-in-cell phenomenon associates with aggressive characteristics and cancer-related mortality in early oral tongue cancer

Almangush, A., Mäkitie, A. A., Hagström, J., Haglund, C., Kowalski, L. P., Nieminen, P., Coletta, R. D., Salo, T. & Leivo, I., 3 sep 2020, I : BMC Cancer. 20, 1, 7 s., 843.

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Chronic use of statins and acetylsalicylic acid and incidence of post-endoscopic retrograde cholangiopancreatography acute pancreatitis: A multicenter, prospective, cohort study

Cardenas-Jaen, K., Archibugi, L., Poropat, G., Korpela, T., Maisonneuve, P., Aparicio, J. R., Udd, M., Stimac, D., Arcidiacono, P. G., De Pretis, N., Valente, R., Di Giulio, E., Casellas, J. A., Kylanpaa, L., Hauser, G., Mariani, A., Gabbrielli, A., Lohr, M., Vanella, G., Rainio, M. & 5 andra, Brozzi, L., Arnelo, U., Fagerstrom, N., Capurso, G. & de-Madaria, E., 28 sep 2020, I : Digestive Endoscopy. 9 s.

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Clinical management of 52 consecutive retro-rectal tumours treated at a tertiary referral centre

Carpelan-Holmström, M., Koskenvuo, L., Haapamäki, C. & Renkonen-Sinisalo, L., 18 maj 2020, I : Colorectal Disease. 7 s.

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Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients

Dickinson, A., Saraswat, M., Syrjänen, S., Tohmola, T., Silén, R., Randén-Brady, R., Carpén, T., Hagström, J., Haglund, C., Mattila, P., Mäkitie, A., Joenväärä, S. & Silén, S., 15 jun 2020, I : PLoS One. 15, 6, 13 s., 0233974.

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Comparison of operative link for gastritis assessment, operative link on gastric intestinal metaplasia assessment, and TAIM stagings among men with atrophic gastritis

Nieminen, A. A., Kontto, J., Puolakkainen, P., Virtamo, J. & Kokkola, A., 28 jun 2020, I : World Journal of Gastroenterology. 26, 24, s. 3447-3457 11 s.

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Comparison of supervised machine learning classification techniques in prediction of locoregional recurrences in early oral tongue cancer

Alabi, R. O., Elmusrati, M., Sawazaki-Calone, I., Kowalski, L. P., Haglund, C., Coletta, R. D., Mäkitie, A. A., Salo, T., Almangush, A. & Leivo, I., apr 2020, I : International Journal of Medical Informatics. 136, 8 s., 104068.

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Diclofenac does not reduce the risk of acute pancreatitis in patients with primary sclerosing cholangitis after endoscopic retrograde cholangiography

Koskensalo, V., Tenca, A., Udd, M., Lindström, O., Rainio, M., Jokelainen, K., Kylänpää, L. & Färkkilä, M., maj 2020, I : United european gastroenterology journal. 8, 4, s. 462-471 10 s.

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Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers

Blatter, R., Tschupp, B., Aretz, S., Bernstein, I., Colas, C., Evans, D. G., Genuardi, M., Hes, F. J., Hueneburg, R., Jarvinen, H., Lalloo, F., Moeslein, G., Renkonen-Sinisalo, L., Resta, N., Spier, I., Varvara, D., Vasen, H., Latchford, A. R. & Heinimann, K., 13 maj 2020, I : Genetics In medicine. 9 s.

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Doxapram as an additive to propofol sedation for endoscopic retrograde cholangiopancreatography: a placebo-controlled, randomized, double-blinded study

Jokelainen, J., Belozerskikh, A., Mustonen, H., Udd, M., Kylänpää, L., Lindström, O., Mazanikov, M. & Pöyhiä, R., 28 jan 2020, I : Surgical Endoscopy. 7 s.

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Dysplasia in the mucosal biopsy specimen is still a warning sign of cancer in ulcerative colitis

Karjalainen, E. K., Renkonen-Sinisalo, L. & Lepistö, A. H., 14 jul 2020, I : Scandinavian Journal of Gastroenterology. 5 s.

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Effect And Predictive Value Of Routine Preoperative Laboratory Testing For Endoscopic Retrograde Cholangiopancreatography

Jokelainen, J., Ismail, S., Kylänpää, L., Udd, M., Mustonen, H., Lindström, O. & Pöyhiä, R., jun 2020, I : Scandinavian Journal of Surgery. 109, 2, s. 115-120 6 s.

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Ei-alkoholiperäinen rasvamaksatauti (NAFLD)

Yki-Järvinen, H., Arkkila, P., Eskelinen, S., Juuti, A., Lapatto, R., Lempiäinen, A., Mervaala, E., Schwab Nikkola, A. & Winterfeld, U., 2020, I : Duodecim. 136, 4, s. 403-405 3 s.

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Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma

Kylmä, A. K., Tolvanen, T. A., Carpén, T., Haglund, C., Mäkitie, A., Mattila, P. S., Grenman, R., Jouhi, L., Sorsa, T., Lehtonen, S. & Hagström, J., jun 2020, I : Experimental and Molecular Pathology. 114, 9 s., 104435.

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Epstein-Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact

Carpen, T., Syrjänen, S., Jouhi, L., Randen-Brady, R., Haglund, C., Mäkitie, A., Mattila, P. S. & Hagström, J., aug 2020, I : Cancer Immunology, Immunotherapy. 69, 8, s. 1615-1626 12 s.

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Evaluation of Adjuvant Chemotherapy in Patients With Resected Pancreatic Cancer After Neoadjuvant FOLFIRINOX Treatment

European-African, van Roessel, S., van Veldhuisen, E., Klompmaker, S., Tarvainen, T. & Besselink, M. G., 10 sep 2020, I : JAMA Oncology. 8 s.

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Executive summary: WSES Guidelines for the management of severe acute pancreatitis

Leppäniemi, A., Tolonen, M., Tarasconi, A., Segovia-Lohse, H., Gamberini, E., Kirkpatrick, A. W., Ball, C. G., Parry, N., Sartelli, M., Wolbrink, D., van Goor, H., Baiocchi, G., Ansaloni, L., Biffl, W., Coccolini, F., Di Saverio, S., Kluger, Y., Moore, E. E. & Catena, F., jun 2020, I : Journal of trauma and acute care surgery. 88, 6, s. 888-890 3 s.

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Factors associated with decision-making on prophylactic hysterectomy and attitudes towards gynecological surveillance among women with Lynch syndrome (LS): a descriptive study

Kalamo, M. H., Mäenpää, J. U., Seppälä, T. T., Mecklin, J. P., Huhtala, H., Sorvettula, K., Pylvänäinen, K. & Staff, S., apr 2020, I : Familial Cancer. 19, 2, s. 177-182 6 s.

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Gut Microbiota and Host Gene Mutations in Colorectal Cancer Patients and Controls of Iranian and Finnish Origin

Sarhadi, V., Lahti, L., Saberi, F., Youssef, O., Kokkola, A., Karla, T., Tikkanen, M., Rautelin, H., Puolakkainen, P., Salehi, R. & Knuutila, S., mar 2020, I : Anticancer Research. 40, 3, s. 1325-1334 10 s.

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Hydroxysteroid 17-beta dehydrogenase 13 variant increases phospholipids and protects against fibrosis in nonalcoholic fatty liver disease

Luukkonen, P. K., Tukiainen, T., Juuti, A., Sammalkorpi, H., Haridas, P. A. N., Niemelä, O., Arola, J., Orho-Melander, M., Hakkarainen, A., Kovanen, P. T., Dwivedi, O., Groop, L., Hodson, L., Gastaldelli, A., Hyötyläinen, T., Oresic, M. & Yki-Järvinen, H., 12 mar 2020, I : JCI INSIGHT. 5, 5, 12 s., 132158.

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Incidence and management of patients with colorectal cancer and synchronous and metachronous colorectal metastases: a population-based study

Väyrynen, V., Wirta, E. -V., Seppälä, T., Sihvo, E., Mecklin, J. -P., Vasala, K. & Kellokumpu, I., aug 2020, I : BMJ Open. 4, 4, s. 685-692 8 s.

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In HPV-negative oropharyngeal squamous cell carcinoma, elevated toll-like receptor 2 immunoexpression may increase the risk of disease-specific mortality

Kylmä, A. K., Jouhi, L., Mohamed, H., Randen-Brady, R., Mäkitie, A., Atula, T., Haglund, C., Sorsa, T. & Hagström, J., aug 2020, I : Oral Oncology. 107, 8 s., 104778.

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Iäkkään naisen vatsakipu

Pekkarinen, P. & Leppäniemi, A., 2020, I : Finnanest.. 53, 1, s. 54-57 4 s.

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Label-free proteomics reveals serum proteins whose levels differ between pancreatic ductal adenocarcinoma patients with short or long survival

Holm, M., Saraswat, M., Joenväärä, S., Seppänen, H., Renkonen, R. & Haglund, C., 25 jun 2020, I : Tumor Biology. 42, 6, 10 s., 1010428320936410.

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MMP-7, -8, -9, E-cadherin, and beta-catenin expression in 34 ameloblastoma cases

Kelppe, J., Thoren, H., Haglund, C., Sorsa, T. & Hagström, J., 28 sep 2020, I : Clinical and Experimental Dental Research. 7 s.

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Molecular Basis of Mismatch Repair Protein Deficiency in Tumors from Lynch Suspected Cases with Negative Germline Test Results

Olkinuora, A., Gylling, A., Almusa, H., Eldfors, S., Lepistö, A., Mecklin, J-P., Nieminen, T. T. & Peltomäki, P., jul 2020, I : Cancers. 12, 7, 15 s., 1853.

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N-glycomic profiling of colorectal cancer according to tumor stage and location

Holm, M., Nummela, P., Heiskanen, A., Satomaa, T., Kaprio, T., Mustonen, H., Ristimäki, A. & Haglund, C., 29 jun 2020, I : PLoS One. 15, 6, 16 s., 0234989.

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Oncogenic Herpesvirus Engages Endothelial Transcription Factors SOX18 and PROX1 to Increase Viral Genome Copies and Virus Production

Gramolelli, S., Elbasani, E., Tuohinto, K., Nurminen, V., Günther, T., Kallinen, R. E., Kaijalainen, S. P., Diaz, R., Grundhoff, A., Haglund, C., Ziegelbauer, J. M., Pellinen, T., Bower, M., Francois, M. & Ojala, P. M., 1 aug 2020, I : Cancer Research. 80, 15, s. 3116-3129 14 s.

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Open necrosectomy in acute pancreatitis-obsolete or still useful?

Husu, H. L., Kuronen, J. A., Leppäniemi, A. K. & Mentula, P. J., 17 mar 2020, I : World journal of emergency surgery. 15, 1, 9 s., 21.

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Outcomes and quality of life after major bile duct injury in long-term follow-up

Koppatz, H., Sallinen, V., Mäkisalo, H. & Nordin, A., 22 jun 2020, I : Surgical Endoscopy. 10 s.

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Patterns of axillary staging and management in clinically node positive breast cancer patients treated with neoadjuvant systemic therapy: Results of a survey amongst breast cancer specialists

Simons, J. M., Maaskant-Braat, A. J. G., Luiten, E. J. T., Leidenius, M. H. K., van Nijnatten, T. J. A., Boelens, P. G., Koppert, L. B., van der Pol, C. C., van de Velde, C. J. H., Audisio, R. A. & Smidt, M. L., jan 2020, I : European Journal of Surgical Oncology. 46, 1, s. 53-58 6 s.

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Performance of Finnish biobanks in nationwide pulmonary carcinoid tumour research

Vesterinen, T., Salmenkivi, K., Mustonen, H., Kuopio, T., Lappi-Blanco, E., Paavonen, T., Vainio, P., Knuuttila, A., Carpén, O., Haglund, C. & Arola, J., feb 2020, I : Virchows Archiv. 476, 2, s. 273-283 11 s.

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Plasma protein expression differs between colorectal cancer patients depending on primary tumor location

Holm, M., Joenväärä, S., Saraswat, M., Tohmola, T., Ristimäki, A., Renkonen, R. & Haglund, C., jul 2020, I : Cancer medicine . 9, 14, s. 5221-5234 14 s.

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