Institutet för molekylärmedicin i Finland

  • Finland

  • Tukholmankatu 8, Biomedicum 2

    Helsinki

    Finland

Publikationer 1966 2020

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2019

Multivariate GWAS of inflammatory markers reveals novel disease associations

Ruotsalainen, S. E., Partanen, J., Surakka, I., Pirinen, M., Salomaa, V., Salmi, M., Jalkanen, S., Daly, M. J., Ripatti, S. & Koskela, J., 10 okt 2019, I : European Journal of Human Genetics. 27, 11, s. 1156-1157 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

POLYGENIC HYPERLIPIDEMIA INCREASES CORONARY ARTERY DISEASE RISK IN THE UK BIOBANK

Ripatti, P., Ramo, J. T., Soderlund, S., Surakka, I., Havulinna, A. S., Widen, E., Palta, P., Freimer, N. B., Salomaa, V., Pirinen, M., Palotie, A., Taskinen, M. R. & Ripatti, S., aug 2019, I : Atherosclerosis. 287, s. E92-E92 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2018
Öppen tillgång

Efficient fine-mapping to identify causal genetic variants and quantify their contribution to complex phenotypes

Benner, C., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., okt 2018, I : Genetic Epidemiology. 42, 7, s. 688-689 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Eltrombopag Promotes Megakaryocyte Survival and Signaling in the Presence of Specific Cytotoxic Agents

Javarappa, K. K., Tsallos, D., Zagidullin, B., Saad, J., Tang, J., Ramos, P. M., Pallaud, C. & Heckman, C. A., 2018, I : Blood. 132

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Genome-Scale CRISPR Screens Identify Essential Genes for Sensitivity to Natural Killer Cells in Hematological Malignancies

Dufva, O., Klievink, J., Saeed, K., Kankainen, M., Ilander, M., Hannunen, T., Lagstrom, S., Ellonen, P., Lee, D. A. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Öppen tillgång

Tool development: increasing preschoolers' ability to delay gratification

Erkkola, M., Vepsäläinen, H., Ray, C., Suhonen, E., Lehtovirta, M., Skaffari, E. & Sajaniemi, N., nov 2018, I : European Journal of Public Health. 28, s. 427-427 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2017

DISC1 GENE NETWORK MUTATIONS IN MAJOR MENTAL ILLNESS

Sinha, V., Ortega-Alonso, A., Ukkola-Vuoti, L., Hovatta, I., Haukka, J., Torniainen, M., Therman, S., Cannon, T., Kaprio, J., Lonnqvist, J., Partonen, T., Isometsa, E., Paunio, T., Suvisaari, J. & Hennah, W., okt 2017, I : European Neuropsychopharmacology. 27, s. S406-S407 2 s., M57.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Effect of Reference Panel in ID Score Regression Analysis of Lipid Traits in the Finnish Population

Hautakangas, H., Havulinna, A. S., Salomaa, V., Ripatti, S. & Pirinen, M., 2017, I : Human Heredity. 83, 1, s. 10-10 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Epigenetic clock at birth and psychiatric problems during early childhood

Suarez, A., Lahti, J., Czamara, D., Lahti, M., Knight, A. K., Girchenko, P., Hämäläinen, E., Kajantie, E., Laivuori, H., Villa, P. M., Reynolds, R. M., Smith, A. K., Binder, E. B. & Räikkönen, K., sep 2017, I : Psychoneuroendocrinology. 83S, s. 52-52 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskning

Öppen tillgång
Fil

Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 jul 2017, I : Cancer Research. 77, 13 Supplement, s. 673 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

High Amount of PD-L1+Tumor Associated Macrophages Is Associated with Better Survival in Patients with Primary Testicular Lymphoma

Pollari, M., Bruck, O., Leivonen, S-K., Pellinen, T., Vahamurto, P., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 dec 2017, I : Blood. 130, Suppl 1, s. Meeting Abstract: 2761 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

IMMUNOLOGICAL CHARACTERIZATION OF PH plus ALL BONE MARROW BY MULTIPLEX IMMUNOHISTOCHEMISTRY

Hohtari, H., Bruck, O., Blom, S., Turkki, R., Ribeiro, A., Sinisalo, M., Kovanen, P., Kallioniemi, O., Pellinen, T., Porkka, K. & Mustjoki, S., 26 jun 2017, I : Haematologica. 102, s. 654-654 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Low Expression of T/NK-Cell Signature Predicts Poor Survival in Patients with Primary Testicular and Diffuse Large B-Cell Lymphoma

Leivonen, S-K., Pollari, M., Bruck, O., Pellinen, T., Karjalainen-Lindsberg, M-L., Mannisto, S., Kellokumpu-Lehtinen, P-L., Mustjoki, S. & Leppa, S., 7 dec 2017, I : Blood. 130, 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

PHENOTYPIC TRANSLATION OF THE DISC1 NETWORK HIGHLIGHTS THE ROLE OF THE NDE1 LOCUS, WITH PHARMACOLOGICAL IMPLICATIONS

Hennah, W., Bradshaw, N., Pankakoski, M., Ortega-Alonso, A., Torniainen, M., Paunio, T., Suvisaari, J., Lonnqvist, J. & Haukka, J., okt 2017, I : European Neuropsychopharmacology. 27, s. S510-S511 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Population-Specific Imputation Reference Panel as a Tool for GWAS Analysis

Kals, M., Palta, P. & Magi, R., 2017, I : Human Heredity. 83, 1, s. 13-13 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Searching for Genetic Variants Matching a Given Multivariate Target Profile

Topa, H., Havulinna, A. S., Salomaa, V., Kähönen, M., Lehtimaki, T., Raitakari, O. T., Järvelin, M-R., Ala-Korpela, M., Wurtz, P. & Pirinen, M., 2017, I : Human Heredity. 83, 1, s. 25-26 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Triplets, birthweight and left-handedness

Heikkila, K., Van Beijsterveldt, T., Haukka, J., Iivanainen, M., Saari-Kemppainen, A., Boomsma, D., Yokoyama, Y. & Vuoksimaa, E., nov 2017, I : Behavior Genetics. 47, 6, s. 686-686 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2016

DECREASED MU-OPIOD RECEPTOR BINDING IN PATHOLOGICAL GAMBLING: A PET STUDY WITH [11C]CARFENTANIL

Majuri, J., Joutsa, J., Johansson, J., Alakurtti, K., Parkkola, R., Lahti, T., Alho, H., Arponen, E. & Kaasinen, V., jun 2016, I : Journal of Cerebral Blood Flow and Metabolism. 36, s. 718-718 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Immune cell profiling in CML bone marrow by multiplex IHC

Bruck, O., Blom, S., Turkki, R., Kovanen, P., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., nov 2016, I : Annals of Oncology. 27, 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Immune Cell Profiling in CML Bone Marrow By Multiplex Immunohistochemistry

Oscar, B., Blom, S., Turkki, R., Kovanen, P. E., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., 2 dec 2016, I : Blood. 128, 22, 4 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Lymphoid somatic mutations in multiple sclerosis

Valori, M., Jansson, L., Kiviharju, A., Porkka, K., Ellonen, P., Mustjoki, S. & Tienari, P., sep 2016, I : Multiple Sclerosis Journal . 22, s. 170-171 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Mutational Landscape of Aggressive Natural Killer Cell Leukemia and Drug Sensitivity Profiling Reveal Therapeutic Options in Natural Killer Cell Malignancies

Dufva, O., Kankainen, M., Kelkka, T., Awad, S. A., Sekiguchi, N., Yadav, B., Eldfors, S., Kuusanmaki, H., Andersson, E. I., Malani, D., Pietarinen, P., Saikko, L., Kovanen, P. E., Suzumiya, J., Suzuki, R., Ko, Y. H., Kim, W. S., Chuang, S-S., Loughran, T. P., Chan, W. C. & 4 andra, Ohshima, K., Aittokallio, T., Ishida, F. & Mustjoki, S., 2 dec 2016, I : Blood. 128, 22, 4 s., 2921.

Forskningsoutput: TidskriftsbidragMötesabstraktForskning

Novel Mutations in Patients with Blast Crisis or Accelerated Phase Chronic Myeloid Leukemia

Awad, S. A., Kankainen, M., Eldfors, S., Kytola, S., Ellonen, P., Kamel, M., Heckman, C. A., Porkka, K. & Mustjoki, S., 2 dec 2016, I : Blood. 128, 22, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Somatic MED12 mutations in hematological malignancies

Heikkinen, T., Kampjarvi, K., Leppa, S., Hokland, P., Kuusanmaki, H., Mustjoki, S., Sinisalo, M., Heckman, C., Kontro, M. & Vahteristo, P., jul 2016, I : Cancer Research. 76, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

SOMATIC MUTATIONS IN CLONALLY EXPANDED CD8(+) T CELLS IN PATIENTS WITH NEWLY DIAGNOSED RHEUMATOID ARTHRITIS

Kelkka, T., Savola, P., Rajala, H., Kuuliala, A., Kuuliala, K., Eldfors, S., Ellonen, P., Lagstrom, S., Khajuria, R. K., Jaatinen, T., Koivuniemi, R., Repo, H., Saarela, J., Porkka, K., Leirisalo-Repo, M. & Mustjoki, S., feb 2016, I : Annals of the Rheumatic Diseases. 75, s. A47-+ 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskning

UNSTABLE LDL - NOVEL MECHANISM OF ATHEROGENESIS AND LINK TO CARDIOVASCULAR DEATHS

Ruuth, M., Nguyen, S. D., Vihervaara, T., Laajala, T. D., Uusitupa, M., Schwab, U., Savolainen, M., Sinisalo, J., Aittokallio, T., Kakela, R., Jauhiainen, M., Kovanen, P. & Oorni, K., sep 2016, I : Atherosclerosis. 252, s. E208-E208 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2015

Large Granular Lymphocyte Infiltration in the Bone Marrow in Children and Young Adults May Suggest Primary Immune Deficiency

Taskinen, M. H., Mustjoki, S., Jahnukainen, K., Trotta, L., Siitonen, T., Hautala, T., Zavialov, A., Heiskanen, K., Haapaniemi, E. M., Saarela, J. & Seppanen, M., 3 dec 2015, I : Blood. 126, 23, 3 s., 1024.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2014

Acinetobacter in the skin microbiota protects from atopic sensitisation

Fyhrquist, N. T., Ruokolainen, L., Suomalainen, A., Lehtimaki, S., Veckman, V., Vendelin, J., Karisola, P., Savinko, T., Lehto, M., Jarva, H., Kosunen, T., Corander, J., Petri, A., von Hertzen, L., Laatikainen, T., Mäkelä, M., Haahtela, T., Greco, D., Hanski & Alenius, H., sep 2014, I : Allergy : European journal of allergy and clinical immunology. 69, s. 4-5 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Characterization of the Microrna Expression Profiles of Paired Primary and Relapsed Diffuse Large B-Cell Lymphoma (DLBCL) By Next-Generation Sequencing

Leivonen, S-K., Icay, K., Liu, C., Taskinen, M., Lehtonen, R., Karjalainen-Lindsberg, M-L., Delabie, J., Holte, H., Hautaniemi, S. & Leppa, S., 6 dec 2014, I : Blood. 124, 21, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2013

High-throughput drug screening and molecular profiling for therapeutic targeting of NUP98-NSD1-positive AML

Kontro, M. P., Pemovska, T., Heckman, C. A., Kallioniemi, O-P., Wennerberg, J. K. & Porkka, K. V. K., feb 2013, I : Annals of Hematology. 92, Supplement 1, s. S18

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Stromal cell supported high-throughput screening of primary acute myeloid leukemia cells for assessing sensitivity to cytotoxic drugs

Karjalainen, R. J., Pemovska, T., Yadav, B., Wennerberg, J. K. & Heckman, C. A., feb 2013, I : Annals of Hematology. 92, Supplement 1, s. S17

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2012

Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia

Rajala, H. L. M., Eldfors, S., Kuusanmaki, H., Andersson, E. I., van Adrichem, A. J., Lagstrom, S., Olson, T., Jerez, A., Clemente, M. J., Zhang, D., Awwad, A., Pihlman, M., Ellonen, P., Kallioniemi, O., Wennerberg, K., Porkka, K., Maciejewski, J. P., Loughran, T. P., Heckman, C. A. & Mustjoki, S., 16 nov 2012, I : Blood. 120, 21, 2 s., Meeting Abstract: 871.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Somatic PTPRT and ANGPT2 Mutations in Large Granulocyte Leukemia

Andersson, E. I., Eldfors, S., Koskela, H. L. M., Ellonen, P., Olson, T., Jerez, A., Clemente, M. J., Kallioniemi, O., Porkka, K., Loughran, T. P., Maciejewski, J. P., Heckman, C. & Mustjoki, S., 16 nov 2012, I : Blood. 120, 21, 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2011

Inhibition of HER2 Positive Breast Cancer Cells by Drug Screening

Nyberg, S., Hongisto, V., Tadele, D. S., Leivonen, S. K., Edgren, H., Kallioniemi, O., Borresen-Dale, A. L., Perala, M. & Sahlberg, K. K., sep 2011, I : European Journal of Cancer. 47, s. S330-S331 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Systematic analysis of microRNAs targeting the androgen receptor in prostate cancer cells

Ostling, P., Leivonen, S-K., Aakula, A., Kohonen, P., Makela, R., Hagman, Z., Edsjo, A., Kangaspeska, S., Edgren, H., Nicorici, D., Bjartell, A., Ceder, Y., Perala, M. & Kallioniemi, O., 15 apr 2011, I : Cancer Research. 71, 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2010

Functional identification of microRNA targets by integrated proteomics and microarray profiling: miR-193b in breast cancer

Leivonen, S-K., Rokka, A., Östling, P., Kohonen, P., Corthals, G., Perala, M. & Kallioniemi, O., apr 2010, I : Cancer Research. 70, suppl 8, 3 s., 1953.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Systematic functional analysis of microRNAs by transfection of 1129 miRNAs into prostate cancer cells

Ostling, P., Leivonen, S-K., Aakula, A., Kohonen, P., Makela, R., Perala, M. & Kallioniemi, O., apr 2010, I : Cancer Research. 70, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2008

Extreme Male/Female Brain Defined with Two Neuropsychological Tests

Vuoksimaa, E., Tuulio-Henriksson, A., Hokkanen, L., Kaprio, J. & Rose, R. J., nov 2008, I : Behavior Genetics. 38, 6, s. 652-652 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2005

Genome-wide genetic linkage analysis of a quantitative trait in an Australian and Finnish study of nicotine dependence

Saccone, S., Agrawal, A., Pergadia, M., Dick, D., Todorov, A., Loukola, A., Broms, U., Maunu, H., Widen, E., Heikkila, K., Rice, J., Montgomery, G., Martin, N., Kaprio, J., Palotie, L. & Madden, P., 2005, I : American journal of medical genetics. Part B, Neuropsychiatric genetics. 138B, s. 16-16 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

1999

Expression of collagens XV, XVII and XVIII and endostatin in oral squamous cell carcinomas

Parikka, M., Kainulainen, T., Tasanen, K., Rehn, M., Hagg, P., Saarela, J., Bruckner-Tuderman, L., Pihlajaniemi, T. & Salo, T., dec 1999, I : Journal of Investigative Dermatology. 113, 6, s. 1145-1145 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

1998

Type XVIII collagen in oral lichen planus and squamous cell carcinoma.

Kainulainen, T., Salo, T., Pihlajaniemi, T. & Rehn, M., 1998, I : Journal of Dental Research. 77, s. 1009-1009 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

1994

HUMAN TUMOR-ASSOCIATED TRYPSIN(OGEN)-2 ACTIVATES 3 GENETICALLY DISTINCT BUT STRUCTURALLY HOMOLOGOUS HUMAN PRO-MATRIX METALLOPROTEINASES

SORSA, T., KNAUPER, KOIVUNEN, E., SALO, T., MURPHY, G., KONTTINEN, YT., WILHELM, S., TSCHESCHE, H. & STENMAN, UH., 1994, I : Journal of Dental Research. 73, s. 201-201 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review