Publikationer 2015 2019

2019

A potent partial agonist of PKC orients in membranes like the biological activator diacylglycerol

Lautala, S., Koivuniemi, A., Kulig, W., Rog, T., Talman, V., Tuominen, R. & Bunker, A., jul 2019, I : European Biophysics Journal. 48, s. S122-S122 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

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Design and evaluation of a multiplexed angular-scanning surface plasmon resonance system employing line-laser optics and CCD detection in combination with multi-ligand sensor chips

Lakayan, D., Tuppurainen, J., Suutari, T. E., van Iperen, D. J., Somsen, G. W. & Kool, J., 1 mar 2019, I : Sensors and Actuators B: Chemical. 282, s. 243-250 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Determinants of Orexin Receptor Binding and Activation—A Molecular Dynamics Study

Karhu, L., Magarkar, A., Bunker, A. & Xhaard, H., 28 mar 2019, I : Journal of Physical Chemistry B. 123, 12, s. 2609-2622 14 s.

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ORP2 interacts with phosphoinositides and controls the subcellular distribution of cholesterol

Koponen, A., Arora, A., Takahashi, K., Kentala, H., Kivela, A. M., Jaaskelainen, E., Peranen, J., Somerharju, P., Ikonen, E., Viitala, T. & Olkkonen, V. M., mar 2019, I : Biochimie. 158, s. 90-101 12 s.

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Real-Time Label-Free Targeting Assessment and in Vitro Characterization of Curcumin-Loaded Poly-lactic-co-glycolic Acid Nanoparticles for Oral Colon Targeting

Akl, M. A., Kartal-Hodzic, A., Suutari, T., Oksanen, T., Montagner, I. M., Rosato, A., Ismael, H. R., Afouna, M. I., Caliceti, P., Yliperttula, M., Samy, A. M., Mastrotto, F., Salmaso, S. & Viitala, T., 1 okt 2019, I : ACS Omega.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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The catalytic mechanism of MB-COMT: new drug design paradigm?

Bunker, A., Rog, T., Magarkar, A., Parkkila, P., Lajunen, T., Mobarak, E., Cramariuc, O., Licari, G. & Vauthey, E., jul 2019, I : European Biophysics Journal. 48, s. S63-S63 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2018

3D label free bio-transfer standards

Järvinen, M., Vainikka, T., Viitala, T., Bermudez, C., Artigas, R., Nolvi, A., Martinez, P., Sandler, N., Hæggström, E. & Kassamakov, I., 7 nov 2018, I : Proceedings of SPIE, the International Society for Optical Engineering. 10819, 8 s., 108190D.

Forskningsoutput: TidskriftsbidragKonferensartikelVetenskapligPeer review

AN ARTIFACT FOR DETERMINING RESOLUTION OF IMAGING BASED ON ELECTROMAGNETIC RADIATION AND/OR MECHANICAL WAVES

Haeggström, E. O., Kassamakov, I. V., Nolvi, A., Sandler, N., Viitala, T. J. S. & Nyman, J., 29 jun 2018, IPC-nr. G01B11/06, G01B21/04, G01B9/02, University of Helsinki, Patentnr. CA3022161 (A1), 16 nov 2017, Prioritetsnummer FI20160005400 20160510; WO2017FI50353 20170508

Forskningsoutput: PatentVetenskaplig

Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements

Parkkila, P., Elderdfi, M., Bunker, A. & Viitala, T., 10 jul 2018, I : Langmuir. 34, 27, s. 8081-8091 11 s.

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Comparison of time-gated surface-enhanced raman spectroscopy (TG-SERS) and classical SERS based monitoring of Escherichia coli cultivation samples

Kögler, M., Paul, A., Anane, E., Birkholz, M., Bunker, A., Viitala, T., Maiwald, M., Junne, S. & Neubauer, P., 2018, I : Biotechnology Progress. 34, 6, s. 1533-1542 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Control of Peptide Aggregation and Fibrillation by Physical PEGylation

Ambrosio, E., Podmore, A., dos Santos, A. L. G., Magarkar, A., Bunker, A., Caliceti, P., Mastrotto, F., van der Walle, C. F. & Salmaso, S., okt 2018, I : Biomacromolecules. 19, 10, s. 3958-3969 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Glyceryl Monostearate: Probing the Self Assembly of a Lipid Amenable To Surface Modification for Hepatic Targeting

Marwah, M., Magarkar, A., Ray, D., Aswal, V., Bunker, A. & Nagarsenker, M., 27 sep 2018, I : Journal of Physical Chemistry C. 122, 38, s. 22160-22169 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

High-Generation Amphiphilic Janus-Dendrimers as Stabilizing Agents for Drug Suspensions

Selin, M., Nummelin, S., Deleu, J., Ropponen, J., Viitala, T., Lahtinen, M., Koivisto, J., Hirvonen, J., Peltonen, L., Kostiainen, M. A. & Bimbo, L. M., okt 2018, I : Biomacromolecules. 19, 10, s. 3983-3993 11 s.

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Interaction of lecithin:cholesterol acyltransferase with lipid surfaces and apolipoprotein A-I-derived peptides

Casteleijn, M. G., Parkkila, P. K., Viitala, T. J. S. & Koivuniemi, A. S., apr 2018, I : Journal of Lipid Research. 59, 4, s. 670-683 14 s.

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Membrane bound COMT isoform is an interfacial enzyme: general mechanism and new drug design paradigm

Magarkar, A., Parkkila, P., Viitala, T., Lajunen, T., Mobarak, E., Licari, G., Cramariuc, O., Vauthey, E., Rog, T. & Bunker, A., 11 apr 2018, I : Chemical Communications. 54, 28, s. 3440-3443 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

METHOD FOR CALIBRATING 3D IMAGING AND SYSTEM FOR 3D IMAGING

Haeggström, E. O., Kassamakov, I. V., Nolvi, A., Ylitalo, T. J., Sandler, N., Viitala, T. J. S. & Nyman, J., 17 okt 2018, IPC-nr. G01B9/02, University of Helsinki, Patentnr. CN107407550 (A), 28 nov 2017, Prioritetsnummer FI20140006032 20141124; WO2015FI50744 20151029

Forskningsoutput: PatentVetenskaplig

Personalized Cancer Vaccine Platform for Clinically Relevant Oncolytic Enveloped Viruses

Ylösmäki, E., Malorzo, C., Capasso, C., Honkasalo, O., Fusciello, M., Martins, B., Ylösmäki, L., Louna, A., Feola, S., Paavilainen, H., Peltonen, K., Hukkanen, V., Viitala, T. & Cerullo, V., 5 sep 2018, I : Molecular therapy. 26, 9, s. 2315-2325 11 s.

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pH-Controlled Liposomes for Enhanced Cell Penetration in Tumor Environment

Barattin, M., Mattarei, A., Balasso, A., Paradisi, C., Cantu, L., Del Favero, E., Viitala, T., Mastrotto, F., Caliceti, P. & Salmaso, S., 30 maj 2018, I : ACS Applied Materials & Interfaces. 10, 21, s. 17646-17661 16 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Spin coated chitin films for biosensors and its analysis are dependent on chitin-surface interactions

Casteleijn, M. G., Richardson, D., Parkkila, P. K., Granqvist, N. M., Urtti, A. O. & Viitala, T. J. S., 2018, I : Colloids and Surfaces A: Physicochemical and Engineering Aspects. 539, s. 261-272

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The effect of light sensitizer localization on the stability of indocyanine green liposomes

Lajunen, T., Nurmi, R., Wilbie, D., Ruoslahti, T., Johansson, N. G., Korhonen, O., Rog, T., Bunker, A., Ruponen, M. & Urtti, A., 28 aug 2018, I : Journal of Controlled Release. 284, s. 213-223 11 s.

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2017

16th International Conference on Organized Molecular Films (ICOMF16-LB16): Helsinki, Finland 25-29 July 2016

Viitala, T. J. S. (red.), feb 2017, Les Ulis Cedex A: EDP Sciences-Web of conferences. 40 s. (MATEC Web of Conferences; nr. 98/2017)

Forskningsoutput: Bok/rapportAntologi eller special utgåvaVetenskapligPeer review

A novel in silico framework to improve MHC-I epitopes and break the tolerance to melanoma

Capasso, C., Magarkar, A., Cervera-Carascon, V., Fusciello, M., Feolaf, S., Muller, M., Garofalo, M., Kuryk, L., Tahtinen, S., Pastore, L., Bunker, A. & Cerullo, V., 2017, I : OncoImmunology. 6, 9, 14 s., 1319028.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effect of piroxicam on lipid membranes: Drug encapsulation and gastric toxicity aspects

Wilkosz, N., Rissanen, S., Cyza, M., Szybka, R., Nowakowska, M., Bunker, A., Rog, T. & Kepczynski, M., 30 mar 2017, I : European Journal of Pharmaceutical Sciences. 100, s. 116-125 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effects of Membrane PEGylation on Entry and Location of Antifungal Drug Itraconazole and Their Pharmacological Implications

Dzieciuch-Rojek, M., Poojari, C., Bednar, J., Bunker, A., Kozik, B., Nowakowska, M., Vattulainen, I., Wydro, P., Kepczynski, M. & Rog, T., apr 2017, I : Molecular Pharmaceutics. 14, 4, s. 1057-1070 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Influence of doxorubicin on model cell membrane properties: insights from in vitro and in silico studies

Alves, A. C., Magarkar, A., Horta, M., Lima, J. L. F. C., Bunker, A., Nunes, C. & Reis, S., 24 jul 2017, I : Scientific Reports. 7, 11 s., 6343.

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Interaction of LCAT enzyme with lipid surfaces and apolipoprotein A-I derived peptides

Casteleijn, M. G., Parkkila, P., Viitala, T. & Koivuniemi, A., jul 2017, I : European Biophysics Journal. 46, s. S210-S210 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Interactions between Chloramphenicol, Carrier Polymers, and Bacteria-Implications for Designing Electrospun Drug Delivery Systems Countering Wound Infection

Preem, L., Mahmoudzadeh, M., Putrins, M., Meos, A., Laidmäe, I., Romann, T., Aruväli, J., Härmäs, R., Koivuniemi, A., Bunker, A., Tenson, T. & Kogermann, K., dec 2017, I : Molecular Pharmaceutics. 14, 12, s. 4417-4430 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Multi-parametric surface plasmon resonance platform for studying liposome-serum interactions and protein corona formation

Kari, O. K., Rojalin, T., Salmaso, S., Barattin, M., Jarva, H., Meri, S., Yliperttula, M., Viitala, T. & Urtti, A., 2017, I : Drug Delivery and Translational Research. 7, 2, s. 1-13 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Oligomerization Alters Binding Affinity between Amyloid Beta and a Modulator of Peptide Aggregation

Hilt, S., Rojalin, T., Viitala, T., Koivuniemi, A., Bunker, A., Wachsmann-Hogiu, S., Kalai, T., Hideg, K., Yliperttula, M. & Voss, J. C., 2 nov 2017, I : Journal of Physical Chemistry C. 121, 43, s. 23974-23987 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Real-time fouling monitoring with Raman spectroscopy

Virtanen, T., Reinikainen, S-P., Kögler, M., Mänttäri, M., Viitala, T. & Kallioinen, M., 1 mar 2017, I : Journal of Membrane Science. 525, s. 312-319 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Round Robin test on bio-imaging transfer standard for 3D optical profilers

Nolvi, A. M., Viitala, T. J. S., Garcia Pérez, A., Sandler, N., Haeggström, E. O., Bermudez, C., Artigas, R. & Kassamakov, I. V., 20 feb 2017, Photonic Instrumentation Engineering IV. Soskind, Y. S. & Olson, C. (red.). Bellingham: SPIE, 9 s. (Proceedings ; vol. 10110).

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKonferensbidragVetenskapligPeer review

Stability optimization of microbial surface-enhanced Raman spectroscopy detection with immunomagnetic separation beads

Uusitalo, S., Kögler, M., Välimaa, A-L., Petäjä, J., Kontturi, V., Siitonen, S., Laitinen, R., Kinnunen, M., Viitala, T. & Hiltunen, J., mar 2017, I : Optical Engineering. 56, 3, 7 s., 037102.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Targeting Tumor-Associated Exosomes with Integrin-Binding Peptides

Carney, R. P., Hazari, S., Rojalin, T., Knudson, A., Gao, T., Tang, Y., Liu, R., Viitala, T., Yliperttula, M. & Lam, K. S., maj 2017, I : Advanced Biosystems. 1, 5, 12 s., 1600038.

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The biophysical properties of plasmalogens originating from their unique molecular architecture

Koivuniemi, A., sep 2017, I : FEBS Letters. 591, 18, s. 2700-2713 14 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Time-resolved SERS for characterizing extracellular vesicles

Rojalin, T., Saari, H., Somersalo, P., Laitinen, S., Turunen, M., Viitala, T., Wachsmann-Hogiu, S., Smith, Z. J. & Yliperttula, M., 2017.

Forskningsoutput: KonferensbidragPosterForskning

Design of cholesterol arabinogalactan anchored liposomes for asialoglycoprotein receptor mediated targeting to hepatocellular carcinoma: In silico modeling, in vitro and in vivo evaluation

Pathak, P., Dhawan, V., Magarkar, A., Danne, R., Govindarajan, S., Ghosh, S., Steiniger, F., Chaudhari, P., Gopal, V., Bunker, A. E., Rog, T., Fahr, M. & Nagarsenker, M., 23 maj 2016, I : International Journal of Pharmaceutics. 509, 1-2, s. 149-158 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Detection of Listeria innocua on roll-to-roll produced SERS substrates with gold nanoparticles

Uusitalo, S., Kogler, M., Välimaa, A. -L., Popov, A., Ryabchikov, Y., Kontturi, V., Siitonen, S., Petäjä, J., Virtanen, T., Laitinen, R., Kinnunen, M., Meglinski, I., Kabashin, A., Bunker, A., Viitala, T. & Hiltunen, J., 2016, I : RSC Advances. 6, 67, s. 62981-62989 9 s.

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Enhancement of Bioavailability and Pharmacodynamic Effects of Thymoquinone Via Nanostructured Lipid Carrier (NLC) Formulation

Elmowafy, M., Samy, A., Raslan, M. A., Salama, A., Said, R. A., Abdelaziz, A. E., El-Eraky, W., El Awdan, S. & Viitala, T., jun 2016, I : AAPS PharmSciTech. 17, 3, s. 663-672 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Factorial design formulation optimization and in vitro characterization of curcumin-loaded PLGA nanoparticles for colon delivery

Akl, M. A., Kartal-Hodzic, A., Oksanen, T., Ismael, H. R., Afouna, M. M., Yliperttula, M., Samy, A. M. & Viitala, T., apr 2016, I : Journal of Drug Delivery Science and Technology. 32, part A, s. 10-20 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

Baghirov, H., Karaman, D., Viitala, T., Duchanoy, A., Lou, Y-R., Mamaeva, V., Pryazhnikov, E., Khiroug, L., Davies, C. D. L., Sahlgren, C. & Rosenholm, J. M., 22 aug 2016, I : PLoS One. 11, 8, 22 s., 0160705.

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Fluorescence-suppressed time-resolved Raman spectroscopy of pharmaceuticals using complementary metal-oxide semiconductor (CMOS) single-photon avalanche diode (SPAD) detector

Rojalin, T., Kurki, L., Laaksonen, T., Viitala, T., Kostamovaara, J., Gordon, K. C., Galvis, L., Wachsmann-Hogiu, S., Strachan, C. J. & Yliperttula, M., 2016, I : Analytical and Bioanalytical Chemistry. 408, 3, s. 761-774 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Indocyanine Green-Loaded Liposomes for Light-Triggered Drug Release

Lajunen, T., Kontturi, L-S., Viitala, L., Manna, M., Cramariuc, O., Rog, T., Bunker, A., Laaksonen, T., Viitala, T., Murtomäki, L. & Urtti, A., jun 2016, I : Molecular Pharmaceutics. 13, 6, s. 2095-2107 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Novel cationic polyelectrolyte coatings for capillary electrophoresis

Dusa, F., Witos, J., Karjalainen, E., Viitala, T., Tenhu, H. & Wiedmer, S. K., jan 2016, I : Electrophoresis. 37, 2, s. 363-371 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Oncolytic adenoviruses coated with MHC-I tumor epitopes increase the anti-tumor immunity and efficacy against melanoma

Capasso, C., Hirvinen, M., Garofalo, M., Romaniuk, D., Kuryk, L., Sarvela, T., Vitale, A., Antopolsky, M., Magarkar, A., Viitala, T., Suutari, T., Bunker, A., Yliperttula, M., Urtti, A. & Cerullo, V., 2016, I : OncoImmunology. 5, 4, 11 s., 1105429.

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Photothermally Triggered Lipid Bilayer Phase Transition and Drug Release from Gold Nanorod and Indocyanine Green Encapsulated Liposomes

Viitala, L., Pajari, S., Lajunen, T., Kontturi, L-S., Laaksonen, T., Kuosmanen, P., Viitala, T., Urtti, A. & Murtomaki, L., 10 maj 2016, I : Langmuir. 32, 18, s. 4554-4563 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Printed biotin-functionalised polythiophene films as biorecognition layers in the development of paper-based biosensors

Ihalainen, P., Pesonen, M., Sund, P., Viitala, T., Määttänen, A., Sarfraz, J., Wilen, C-E., Österbacka, R. & Peltonen, J., 28 feb 2016, I : Applied Surface Science. 364, s. 477-483 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Raman spectroscopy of single extracellular vesicles reveals subpopulations with varying membrane content

Smith, Z. J., Lee, C., Rojalin, T., Carney, R. P., Hazari, S., Knudson, A., Lam, K. S., Saari, H., Ibanez, E. L., Viitala, T., Laaksonen, T., Yliperttula, M. & Wachsmann-Hogiu, S., 2016, I : Proceedings of SPIE, the International Society for Optical Engineering. 9704

Forskningsoutput: TidskriftsbidragKonferensartikelVetenskaplig