Foto av Adrian Goldman
  • PL 65 (Viikinkaari 9)



  • Viikinkaari 1, Biocentre 3

    00790 Helsinki


  • Viikinkaari 5, Biocenter 2

    00790 Helsinki


1998 …2024

Forskningsoutput per år

Personlig profil

Information om forskning och undervisning

More than 50%  of current drugs affect membrane proteins and membrane protein systems.  It is thus clear that membranes and the proteins embedded in/associated  with them are key both biologically and medicinally. The proteins and  protein complexes in the membrane create electrochemical gradients,  mediate self:non-self interactions, and control the passage of molecules  and responses to extracellular signals. Despite this, such systems have  been less thoroughly studied than soluble proteins (Engelman, 2005, Nature, 438,  578-80). Steady advances in techniques have made it possible to study  them in lower amounts and with more spatial and temporal precision than  before.


Our work, which aims at spatial cellular/structural biology, thus  focuses on proteins and protein complexes that are at and close to the  cell surface, looking at at neuronal protein interactions  (e.g.  GDNF-GFRα-RET, MANF, and neuronal LRR-proteins) and at host-pathogen  interactions, such as those involving trimeric autotransporters, factor H  and complement. 


Externa befattningar

PI, Marie Curie ITN ViBrANT

1 jan. 201831 dec. 2021

coPI, Marie Curie ITN RAMP

1 apr. 201731 mars 2021


  • 1182 Biokemi, cell- och molekylärbiologi

Internationellt och inhemskt samarbete

Publikationer och projekt inom de senaste fem åren.