Foto på Alex Edwin Bunker

Alex Edwin Bunker

Adjunct Professor, Department of Chemistry, Faculty of Science

  • PL 56 (Viikinkaari 5)

    00014

    Finland

20052019
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Personlig profil

Information om forskning och undervisning

Research:

Myself, along with Dr. Tapani Viitala, share leadership of the Pharmaceutical Biophysics group. Our research combines my computational research methodologies with the experimental research methodologies of Dr. Tapani Viitala, to the development of a mechanistic understanding of the interactions between the three fundamental elements of bionanovectors: lipid membranes, proteins and polymers. We study their behaviour in the bloodstream and, on a more general level, the design principles of safe and efficient drug delivery systems and their interaction with biological membranes and cells. The group is founded on the combined expertise of the two principle investigators with established track records in this field: the experimental research of Dr. Tapani Viitala and the computational research of Dr. Alex Bunker. The combination provides a synergistic framework that, as collaboration, has already provided new insights from new combined experimental-computational methodologies for the analysis of these systems.

Teaching:

I currently teach two courses “advanced mathematical tools for pharmaceutical research” Course #590337 and “Fundamentals of Molecular Modelling and drug design” Course #590287, both at the faculty of pharmacy. Course #590337 is an refresher course in the applied mathematical tools needed for pharmacy research in areas including physical pharmacy, pharmacokinetics and molecular modelling. Course #590287 is an introductory course in molecular modelling taught from the ground up to give the students who have no initial background a basic understanding of the growing use of molecular modelling techniques in pharmaceutical research. 

Meritförteckning

Tekstiä

Vetenskapsgrenar

  • 317 Farmaci
  • 114 Fysik
  • 118 Biovetenskaper
  • 116 Kemi
  • 221 Nanoteknologi

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer 2008 2019

A potent partial agonist of PKC orients in membranes like the biological activator diacylglycerol

Lautala, S., Koivuniemi, A., Kulig, W., Rog, T., Talman, V., Tuominen, R. & Bunker, A., jul 2019, I : European Biophysics Journal. 48, s. S122-S122 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Öppen tillgång
Fil

Determinants of Orexin Receptor Binding and Activation—A Molecular Dynamics Study

Karhu, L., Magarkar, A., Bunker, A. & Xhaard, H., 28 mar 2019, I : Journal of Physical Chemistry B. 123, 12, s. 2609-2622 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

The catalytic mechanism of MB-COMT: new drug design paradigm?

Bunker, A., Rog, T., Magarkar, A., Parkkila, P., Lajunen, T., Mobarak, E., Cramariuc, O., Licari, G. & Vauthey, E., jul 2019, I : European Biophysics Journal. 48, s. S63-S63 1 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Biophysical Characterization of Supported Lipid Bilayers Using Parallel Dual-Wavelength Surface Plasmon Resonance and Quartz Crystal Microbalance Measurements

Parkkila, P., Elderdfi, M., Bunker, A. & Viitala, T., 10 jul 2018, I : Langmuir. 34, 27, s. 8081-8091 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Projekter 2005 2019

Medimmune collaboration research

Bunker, A. E. & Magarkar, A.

01/05/201630/09/2016

Projekt: Forskningsprojekt

Molecular dynamics simulation as a tool to investigate novel formulations for –some based drug delivery systems

Bunker, A. E., Magarkar, A., Karhu, L., Momeni, S. & Mahmoudzadeh, M.

01/09/201531/08/2019

Projekt: Forskningsprojekt

Surface Structure of Nanoparticles

Magarkar, A., Bunker, A. E., Urtti, A., Yliperttula, M. & Rog, T.

02/08/201031/08/2015

Projekt: Forskningsprojekt

Molecular dynamics simulation of DNA - dendrimer interactions

Bunker, A. E. & maiti, P.

10/10/200831/12/2015

Projekt: Forskningsprojekt

Aktiviteter 2005 2018

6th European Joint Theoretical Experimental Meeting on Membranes

Tapani Viitala (Ordförande i organisationskommitté), Alexander Edwin Bunker (Ordförande i organisationskommitté)
12 dec 201814 dec 2018

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Journal of Biological Physics (Tidskrift)

Alex Edwin Bunker (Referentgranskare)
16 maj 2016

Aktivitet: Typer för peer review av output och redaktionsarbeteReferentgranskning av manuskript

Journal of Molecular Biology (Tidskrift)

Alex Edwin Bunker (Referentgranskare)
25 nov 2016

Aktivitet: Typer för peer review av output och redaktionsarbeteReferentgranskning av manuskript

Opponent for Doctoral dissertation of Esra Karakas

Alex Edwin Bunker (Opponent)
9 maj 2016

Aktivitet: ExaminationstyperOpponent i doktorsavhandling

Journal of Controlled Release (Tidskrift)

Alex Edwin Bunker (Referentgranskare)
26 aug 2016

Aktivitet: Typer för peer review av output och redaktionsarbeteReferentgranskning av manuskript

Press / media

Interview for article in "Inside Science"

Alex Edwin Bunker

25/08/2016

1 mediabidrag

Press/media: !!Press / Media