Foto av Astrid Murumägi
  • PL 20 (Tukholmankatu 8)

    00014

    Finland

20032020

Forskningsoutput per år

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Personlig profil

Forskningsintressen

Astrid Murumägi is a senior scientist at the Kallioniemi group. She received her PhD in Molecular Immunology at the University of Tampere.  During her postdoctoral training she transitioned to systems biology and genomics by joining Prof. Olli Kallioniemi´s team at FIMM in 2009. Her work is focused on applying systems medicine in cancer research. She is involved in the FIMM Grand Challenge on Individualized Systems Medicine program. More specifically, she is responsible for ovarian cancer and melanoma functional precision medicine projects, where patient-derived cancer cells are used for comprehensive drug sensitivity testing and molecular profiling to identify best treatment strategies for patients. In addition she is involved in several collaboration projects where the drug testing platform has been applied to uncover novel drug vulnerabilities in cancer cells.

Vetenskapsgrenar

  • 3111 Biomedicinska vetenskaper
  • 318 Medicinsk bioteknologi
  • 3122 Cancersjukdomar

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer

Glucocorticoids induce differentiation and chemoresistance in ovarian cancer by promoting ROR1-mediated stemness

Karvonen, H., Arjama, M., Kaleva, L., Niininen, W., Barker, H., Koivisto-Korander, R., Tapper, J., Pakarinen, P., Lassus, H., Loukovaara, M., Bützow, R., Kallioniemi, O., Murumägi, A. & Ungureanu, D., 23 sep 2020, I : Cell Death and Disease. 11, 9, 12 s., 790.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Anagrelide for Gastrointestinal Stromal Tumor

Pulkka, O-P., Gebreyohannes, Y. K., Wozniak, A., Mpindi, J-P., Tynninen, O., Icay, K., Cervera, A., Keskitalo, S., Murumägi, A., Kulesskiy, E., Laaksonen, M., Wennerberg, K., Varjosalo, M., Laakkonen, P., Lehtonen, R., Hautaniemi, S., Kallioniemi, O., Schöffski, P., Sihto, H. & Joensuu, H., 1 mar 2019, I : Clinical Cancer Research. 25, 5, s. 1676-1687 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Clinical implementation of precision systems oncology in the treatment of ovarian cancer based on ex-vivo drug testing and molecular profiling

Murumagi, A., Ungureanu, D., Khan, S., Hirasawa, A., Arjama, M., Valimaki, K., Mikkonen, P., Niininen, W., Kumar, A., Eldfors, S., Pellinen, T., Pietiainen, V., Magi, A., Koivisto-Korander, R., Tapper, J., Loukovaara, M., Aittokallio, T., Butzow, R. & Kallioniemi, O., jul 2019, I : Cancer Research. 79, 13, 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Wnt5a and ROR1 activate non-canonical Wnt signaling via RhoA in TCF3-PBX1 acute lymphoblastic leukemia and highlight new treatment strategies via Bcl-2 co-targeting

Karvonen, H., Perttila, R., Niininen, W., Hautanen, V., Barker, H., Murumagi, A., Heckman, C. A. & Ungureanu, D., 25 apr 2019, I : Oncogene. 38, 17, s. 3288-3300 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Aktiviteter

  • 12 Arrangemang av och deltagande i konferens/workshop/kurs/seminarium
  • 2 Annan
  • 1 Public Talks
  • 1 !!Invited talk

Precision medicine in oncology

Astrid Murumägi (!!Speaker)

13 sep 2019

Aktivitet: Typer för tal eller presentation!!Invited talk

Functional Drug Screening meeting

Astrid Murumägi (Närvarande)

12 mar 201913 mar 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Functional Precision Medicine Summit

Astrid Murumägi (Närvarande)

30 mar 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

AACR Annual Meeting

Astrid Murumägi (Deltagare)

29 mar 20193 apr 2019

Aktivitet: Andra aktivitetstyperAnnan

National workshop on Personalized/Precision Cancer Medicine (PCM)

Astrid Murumägi (Närvarande)

6 apr 2016

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium