Inget foto av Clare Strachan
  • PL 56 (Viikinkaari 5)

    00014

    Finland

20062020

Forskningsoutput per år

Om du gjort några ändringar i Pure kommer de visas här snart.

Publikationer

2020

Surface stabilization and dissolution rate improvement of amorphous compacts with thin polymer coatings: can we have it all?

Novakovic, D., Peltonen, L., Isomäki, A. O., Fraser-Miller, S. J., Hagner Nielsen, L., Laaksonen, T. & Strachan, C., 6 apr 2020, I : Molecular Pharmaceutics. 17, 4, s. 1248-1260 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2019

Cell-Nanoparticle Interactions at (Sub)-Nanometer Resolution Analyzed by Electron Microscopy and Correlative Coherent Anti-Stokes Raman Scattering

Saarinen, J. K. S., Gütter, F., Lindman, M. M., Agopov, M., Fraser-Miller, S. J., Scherließ, R., Jokitalo, E., Almeida Santos, H., Peltonen, L., Isomäki, A. & Strachan, C. J., apr 2019, I : Biotechnology Journal. 14, 4, 10 s., 1800413.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Chemical analysis using 3D printed glass microfluidics

Gal-Or, E., Gershoni, Y., Scotti, G., Nilsson, S. M. E., Saarinen, J. K. S., Jokinen, V. P., Strachan, C. J., Boije af Gennäs, P. G., Yli-Kauhaluoma, J. T. & Kotiaho, A. A. T., 7 apr 2019, I : Analytical Methods. 11, 13, s. 1802-1810 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Direct Measurement of Amorphous Solubility

Stukelj, J., Svanback, S., Agopov, M., Lobmann, K., Strachan, C. J., Rades, T. & Yliruusi, J., 4 jun 2019, I : Analytical Chemistry. 91, 11, s. 7411-7417 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

Štukelj, J., Svanbäck, S., Kristl, J., Strachan, C. J. & Yliruusi, J., 19 mar 2019, I : Analytical Chemistry. 91, 6, s. 3997-4003 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Tissue-specific study across the stem reveals the chemistry and transcriptome dynamics of birch bark.

Alonso Serra, J. A., Safronov, O., Lim, K-J., Fraser-Miller, S., Blokhina, O. B., Campilho, A., Chong, S-L., Fagerstedt, K. V., Haavikko, R. H., Helariutta, Y., Immanen, J. J. M., Kangasjärvi, J. S., Kauppila, T. J., Lehtonen, M., Ragni, L., Rajaraman, S., Räsänen, R-M., Safdari, P., Tenkanen, T. M., Yli-Kauhaluoma, J. T. & 4 andra, Teeri, T. H., Strachan, C. J., Nieminen, K. & Salojärvi, J. T., jun 2019, I : New Phytologist. 222, 4, s. 1816-1831 16 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2018

Crystallization Kinetics of an Amorphous Pharmaceutical Compound Using Fluorescence-Lifetime-Imaging Microscopy

Rautaniemi, K., Vuorimaa-Laukkanen, E., Strachan, C. J. & Laaksonen, T., maj 2018, I : Molecular Pharmaceutics. 15, 5, s. 1964-1971 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Direct comparison of low- and mid-frequency Raman spectroscopy for quantitative solid-state pharmaceutical analysis

Lipiäinen, T., Fraser-Miller, S. J., Gordon, K. C. & Strachan, C. J., 5 feb 2018, I : Journal of Pharmaceutical and Biomedical Analysis. 149, s. 343-350 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions

Semjonov, K., Salm, M., Lipiäinen, T., Kogermann, K., Lust, A., Laidmäe, I., Antikainen, O., Strachan, C. J., Ehlers, H., Yliruusi, J. & Heinämäki, J., 25 apr 2018, I : International Journal of Pharmaceutics. 541, 1-2, s. 188-197 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Isomalt and its diastereomer mixtures as stabilizing excipients with freeze-dried lactate dehydrogenase

Tuderman, A-K., Strachan, C. J. & Juppo, A. M., 1 mar 2018, I : International Journal of Pharmaceutics. 538, 1-2, s. 287-295 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Time-Gated Raman Spectroscopy for Quantitative Determination of Solid-State Forms of Fluorescent Pharmaceuticals

Lipiäinen, T., Pessi, J., Movahedi, P., Koivistoinen, J., Kurki, L., Tenhunen, M., Yliruusi, J., Juppo, A. M., Heikkonen, J., Pahikkala, T. & Strachan, C. J., 3 apr 2018, I : Analytical Chemistry. 90, 7, s. 4832-4839 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Understanding Dissolution and Crystallization with Imaging: A Surface Point of View

Novakovic, D., Isomäki, A., Pleunis, B., Fraser-Miller, S. J., Peltonen, L. J., Laaksonen, T. & Strachan, C. J., nov 2018, I : Molecular Pharmaceutics. 15, 11, s. 5361-5373 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2017

A minitablet formulation made from electrospun nanofibers

Poller, B., Strachan, C., Broadbent, R. & Walker, G. F., maj 2017, I : European Journal of Pharmaceutics and Biopharmaceutics. 114, s. 213-220 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Elucidation of Compression-Induced Surface Crystallization in Amorphous Tablets Using Sum Frequency Generation (SFG) Microscopy

Mah, P. T., Novakovic, D., Saarinen, J., Landeghem, S. V., Peltonen, L., Laaksonen, T., Isomäki, A. & Strachan, C. J., 2017, I : Pharmaceutical Research. 34, 5, s. 957-970 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Insights into Caco-2 cell culture structure using coherent anti-Stokes Raman scattering (CARS) microscopy

Saarinen, J., Sõzeri, E., Fraser-Miller, S., Peltonen, L., A. Santos, H., Isomäki, A. & Strachan, C. J., 15 maj 2017, I : International Journal of Pharmaceutics. 523, 1, s. 270–280 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Multimodal Nonlinear Optical Imaging for Sensitive Detection of Multiple Pharmaceutical Solid-State Forms and Surface Transformations

Novakovic, D., Saarinen, J., Rojalin, T., Antikainen, O., Fraser-Miller, S., Laaksonen, T., Peltonen, L., Isomäki, A. & Strachan, C. J., 2017, I : Analytical Chemistry. 89, 21, s. 11460-11467 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Probing Pharmaceutical Mixtures during Milling: The Potency of Low-Frequency Raman Spectroscopy in Identifying Disorder

Walker, G., Römann, P., Poller, B., Löbmann, K., Grohganz, H., Rooney, J. S., Huff, G. S., Smith, G. P. S., Rades, T., Gordon, K. C., Strachan, C. J. & Fraser-Miller, S. J., dec 2017, I : Molecular Pharmaceutics. 14, 12, s. 4675-4684 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Supersaturating drug delivery systems: The potential of co-amorphous drug formulations

Laitinen, R., Löbmann, K., Grohganz, H., Priemel, P., Strachan, C. J. & Rades, T., 30 okt 2017, I : International Journal of Pharmaceutics. 532, 1, s. 1-12 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

The formation and physical stability of two-phase solid dispersion systems of indomethacin in supercooled molten mixtures with different matrix formers

Semjonov, K., Kogermann, K., Laidmae, I., Antikainen, O., Strachan, C. J., Ehlers, H., Yliruusi, J. & Heinämäki, J., 15 jan 2017, I : European Journal of Pharmaceutical Sciences. 97, s. 237-246 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2016

Fluorescence-suppressed time-resolved Raman spectroscopy of pharmaceuticals using complementary metal-oxide semiconductor (CMOS) single-photon avalanche diode (SPAD) detector

Rojalin, T., Kurki, L., Laaksonen, T., Viitala, T., Kostamovaara, J., Gordon, K. C., Galvis, L., Wachsmann-Hogiu, S., Strachan, C. J. & Yliperttula, M., 2016, I : Analytical and Bioanalytical Chemistry. 408, 3, s. 761-774 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Physical Stability of Freeze-Dried Isomalt Diastereomer Mixtures

Koskinen, A-K., Fraser-Miller, S. J., Boetker, J. P., Heljo, V. P., Barnsley, J. E., Gordon, K. C., Strachan, C. J. & Juppo, A. M., jul 2016, I : Pharmaceutical Research. 33, 7, s. 1752-1768 17 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Production, applications and in vivo fate of drug nanocrystals

Tuomela, A. L., Saarinen, J. K. S., Strachan, C. J., Hirvonen, J. T. & Peltonen, L. J., 2016, I : Journal of Drug Delivery Science and Technology. 34, s. 21-31 11 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

The effect of surfactants on the dissolution behavior of amorphous formulations

Mah, P. T., Peltonen, L., Novakovic, D., Rades, T., Strachan, C. J. & Laaksonen, T., jun 2016, I : European Journal of Pharmaceutics and Biopharmaceutics. 103, s. 13-22 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Vibrational Spectroscopic Imaging: ( Part V: Imaging Techniques, Chapter17)

Fraser-Miller, S., Saarinen, J. & Strachan, C. J., 2016, Analytical Techniques in the Pharmaceutical Sciences. Müllertz, A., Perrie, Y. & Rades, T. (red.). New York: Springer, s. 523-589 67 s. (Advances in Delivery Science and Technology).

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

2015

Amorphous solid dispersions of piroxicam and Soluplus (R): Qualitative and quantitative analysis of piroxicam recrystallization during storage

Lust, A., Strachan, C. J., Veski, P., Aaltonen, J., Heinämäki, J., Yliruusi, J. & Kogermann, K., 30 maj 2015, I : International Journal of Pharmaceutics. 486, 1-2, s. 306-314 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Differential scanning calorimetry predicts the critical quality attributes of amorphous glibenclamide

Mah, P. T., Laaksonen, T., Rades, T., Peltonen, L. & Strachan, C. J., 1 dec 2015, I : European Journal of Pharmaceutical Sciences. 80, s. 74-81 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Evaluation of vibrational spectroscopic methods to identify and quantify multiple adulterants in herbal medicines

Rooney, J. S., McDowell, A., Strachan, C. J. & Gordon, K. C., 1 jun 2015, I : Talanta. 138, s. 77-85 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Investigation of protein distribution in solid lipid particles and its impact on protein release using coherent anti-Stokes Raman scattering microscopy

Christophersen, P. C., Birch, D., Saarinen, J., Isomaki, A., Nielsen, H. M., Yang, M., Strachan, C. J. & Mu, H., 10 jan 2015, I : Journal of Controlled Release. 197, s. 111-120 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Multimodal Non-Linear Optical Imaging for the Investigation of Drug Nano-/Microcrystal-Cell Interactions

Darville, N., Saarinen, J., Isomäki, A., Khriachtchev, L., Sterkens, P., van Heerden, M., Annaert, P., Peltonen, L., Almeida Santos, H., Strachan, C. J. & Van den Mooter, G., 2 okt 2015, I : European Journal of Pharmaceutics and Biopharmaceutics. 96, s. 338–348 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Polymer incorporation method affects the physical stability of amorphous indomethacin in aqueous suspension

Surwase, S. A., Itkonen, L., Aaltonen, J., Saville, D., Rades, T., Peltonen, L. & Strachan, C. J., okt 2015, I : European Journal of Pharmaceutics and Biopharmaceutics. 96, s. 32-43 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Understanding critical quality attributes for nanocrystals from preparation to delivery

Peltonen, L. & Strachan, C., 2015, I : Molecules. 20, 12, s. 22286-22300

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

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Use of low-frequency Raman spectroscopy and chemometrics for the quantification of crystallinity in amorphous griseofulvin tablets

Mah, P. T., Fraser, S. J., Reish, M. E., Rades, T., Gordon, K. C. & Strachan, C. J., mar 2015, I : Vibrational Spectroscopy. 77, s. 10-16 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2014

Amino Acids as Co-amorphous Excipients for Simvastatin and Glibenclamide: Physical Properties and Stability

Laitinen, R., Lobmann, K., Grohganz, H., Strachan, C. & Rades, T., jul 2014, I : Molecular Pharmaceutics. 11, 7, s. 2381-2389 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Coherent anti-Stokes Raman Scattering (CARS) Microscopy Visualizes Pharmaceutical Tablets During Dissolution

Fussell, A. L., Kleinebudde, P., Herek, J., Strachan, C. & Offerhaus, H. L., 2014, I : Journal of Visualized Experiments. 89, 6 s., e51847.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Coherent Anti-Stokes Raman Scattering Microscopy Driving the Future of Loaded Mesoporous Silica Imaging

L. Fussell, A., Ting Mah, P., Offerhaus, H., Niemi, S-M., Salonen, J., Santos, H. A. & Strachan, C., jul 2014, I : Acta Biomaterialia. 10, 11, s. 4870-4877 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Distribution of binder in granules produced by means of twin screw granulation

Fonteyne, M., Fussell, A. L., Vercruysse, J., Vervaet, C., Remon, J. P., Strachan, C., Rades, T. & De Beer, T., 28 feb 2014, I : International Journal of Pharmaceutics. 462, 1-2, s. 8-10 3 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Influence of postharvest processing and storage conditions on key antioxidants in puha (Sonchus oleraceus L.)

Ou, Z-Q., Schmierer, D. M., Strachan, C. J., Rades, T. & McDowell, A., jul 2014, I : Journal of Pharmacy and Pharmacology. 66, 7, s. 998-1008 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

In situ dissolution analysis of pharmaceutical dosage forms using coherent anti-Stokes Raman scattering (CARS) microscopy

Fussell, A. L., Garbacik, E. T., Löbmann, K., Offerhaus, H. L., Kleinebudde, P. & Strachan, C. J., 28 feb 2014, Multiphoton Microscopy in the Biomedical Sciences XIV. Periasamy, A., So, PTC. & Konig, K. (red.). Bellington: SPIE, 9 s. 89482J. (Proceedings of SPIE, the International Society for Optical Engineering; vol. 8948).

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKonferensbidragVetenskapligPeer review

Stabilized Amorphous Solid Dispersions with Small Molecule Excipients

Löbmann, K., Tarp Jensen, K., Laitinen, R., Rades, T., Strachan, C. J. & Grohganz, H., 2014, Amorphous Solid Dispersions: Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (red.). New York: Springer, s. 613-636 24 s. (Advances in Delivery Science and Technology).

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

Theoretical Considerations in Developing Amorphous Solid Dispersions

Laitinen, R., Priemel, P. A., Surwase, S., Graeser, K., Strachan, C. J., Grohganz, H. & Rades, T., 2014, Amorphous Solid Dispersions: Theory and Practice. Shah, N., Sandhu, H., Choi, D. S., Chokshi, H. & Malick, A. W. (red.). New York: Springer, s. 35-90 56 s. (Advances in Delivery Science and Technology).

Forskningsoutput: Kapitel i bok/rapport/konferenshandlingKapitelVetenskapligPeer review

Unravelling the Relationship between Degree of Disorder and the Dissolution Behavior of Milled Glibenclamide

Mah, P. T., Laaksonen, T., Rades, T., Aaltonen, J., Peltonen, L. & Strachan, C. J., jan 2014, I : Molecular Pharmaceutics. 11, 1, s. 234-242 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2013

Amino acids as co-amorphous stabilizers for poorly water soluble drugs - Part 1: Preparation, stability and dissolution enhancement

Löbmann, K., Grohganz, H., Laitinen, R., Strachan, C. & Rades, T., 2013, I : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 PART B, s. 873-881 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Amino acids as co-amorphous stabilizers for poorly water-soluble drugs - Part 2: Molecular interactions

Löbmann, K., Laitinen, R., Strachan, C., Rades, T. & Grohganz, H., 2013, I : European Journal of Pharmaceutics and Biopharmaceutics. 85, 3 PART B, s. 882-888 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Amorphous drugs and dosage forms

Grohganz, H., Loebmann, K., Priemel, P., Jensen, K. T., Graeser, K., Strachan, C. & Rades, T., 2013, I : Journal of Drug Delivery Science and Technology. 23, 4, s. 403-408 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Application of terahertz pulsed imaging to analyse film coating characteristics of sustained-release coated pellets

Haaser, M., Karrout, Y., Velghe, C., Cuppok, Y., Gordon, K. C., Pepper, M., Siepmann, J., Rades, T., Taday, P. F. & Strachan, C. J., 5 dec 2013, I : International Journal of Pharmaceutics. 457, 2, s. 521-526 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

A theoretical and spectroscopic study of co-amorphous naproxen and indomethacin

Löbmann, K., Laitinen, R., Grohganz, H., Strachan, C., Rades, T. & Gordon, K. C., 2013, I : International Journal of Pharmaceutics. 453, 1, s. 80-87 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Characterization of chitosan-magnesium aluminum silicate nanocomposite films for buccal delivery of nicotine

Pongjanyakul, T., Khunawattanakul, W., Strachan, C. J., Gordon, K. C., Puttipipatkhachorn, S. & Rades, T., apr 2013, I : International Journal of Biological Macromolecules. 55, s. 24-31 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review