David Fewer

Personlig profil

Information om forskning och undervisning

Cyanobacteria form toxic blooms in freshwater lakes, reservoirs and ponds worldwide. These toxic blooms are linked to the death of wild and domestic animals and pose a serious health hazard in the safe production of drinking water. My research focuses on environmental microbiology and biotechnology of toxic cyanobacteria and the secondary metabolites they produce. Many of these specialized metabolites are toxins or odorous compounds that adversely affect the water quality of fresh water bodies and inland fisheries. I am interested in undestanding how these secondary metabolites are made and their application as pharmaceuticals and biomaterials in the emerging circular bio-economy. My research uses a combination of environmental microbiology, genomics and microbial biotechnology.

Utbildning / akademisk kvalifikation

Microbiology, Ph.D., University of Göttingen

Keywords

1183 Växtbiologi, mikrobiologi, virologi

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer 1999 2019

68 Artikel
3 Översiktsartikel
2 Kapitel
2 Patent
1 Mer
- 1 Poster

Phylogenomic Analysis of the Microviridin Biosynthetic Pathway Coupled with Targeted Chemo-Enzymatic Synthesis Yields Potent Protease Inhibitors

Ahmed, M. N., Reyna-Gonzalez, E., Schmid, B., Wiebach, V., Süssmuth, R. D., Dittmann, E. & Fewer, D. P., jun 2017, I : ACS Chemical Biology. 12, 6, s. 1538-1546 9 s.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Natural Product Biosynthetic Diversity and Comparative Genomics of the Cyanobacteria.

Dittmann, E., Gugger, M., Sivonen, A. K. & Fewer, D. P., 5 okt 2015, I : Trends in Microbiology. 23, 10, s. 642-652 11 s.

Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Vetenskaplig › Peer review

Genome mining expands the chemical diversity of the cyanobactin family to include highly modified linear peptides

Leikoski, N., Liu, L., Jokela, J., Wahlsten, M., Gugger, M., Calteau, A., Permi, P., Kerfeld, C., Sivonen, K. & Fewer, D. P., 2013, I : Chemistry & Biology. 20, 8, s. 1033-1043 11 s.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Alternative Biosynthetic Starter Units Enhance the Structural Diversity of Cyanobacterial Lipopeptides

Mares, J., Hajek, J., Urajova, P., Kust, A., Jokela, J., Saurav, K., Galica, T., Capkova, K., Mattila, A., Haapaniemi, E., Permi, P., Mysterud, I., Skulberg, O. M., Karlsen, J., Fewer, D. P., Sivonen, K., Tonnesen, H. H. & Hrouzek, P., feb 2019, I : Applied and Environmental Microbiology. 85, 4, 17 s., UNSP e02675-18.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review