Delivery of CDNF by AAV-mediated gene transfer protects dopamine neurons and regulates ER stress and inflammation in an acute MPTP mouse model of Parkinson’s disease

Nam, J., Richie, C. T., Harvey, B. K. & Voutilainen, M. H., dec. 2024, I: Scientific Reports. 14, 1, 16487.

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CDNF rescues motor neurons in models of amyotrophic lateral sclerosis by targeting endoplasmic reticulum stress

De Lorenzo, F., Lüningschrör, P., Nam, J., Beckett, L., Pilotto, F., Galli, E., Lindholm, P., von Collenberg, C. R., Mungwa, S. T., Jablonka, S., Kauder, J., Thau-Habermann, N., Petri, S., Lindholm, D., Saxena, S., Sendtner, M., Saarma, M. & Voutilainen, M. H., 1 sep. 2023, I: Brain : a journal of neurology. 146, 9, s. 3783–3799 17 s.

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MANF regulates neuronal survival and UPR through its ER-located receptor IRE1α

Kovaleva, V., Yu, L.-Y., Ivanova, L., Shpironok, O., Nam, J., Eesmaa, A., Kumpula, E.-P., Sakson, S., Toots, U., Ustav, M., Huiskonen, J. T., Voutilainen, M. H., Lindholm, P., Karelson, M. & Saarma, M., 28 feb. 2023, I: Cell Reports. 42, 2, 31 s., 112066.

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MANF Is Neuroprotective in Early Stages of EAE, and Elevated in Spinal White Matter by Treatment With Dexamethasone

Nam, J., Koppinen, T. K. & Voutilainen, M. H., 7 juli 2021, I: Frontiers in Cellular Neuroscience. 15, 13 s., 640084.

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