Johan Lundin

Publikationer

Forskningsresultat per år 1994 2021

• 137 Artikel
• 12 Konferensartikel
• 5 Mötesabstrakt
• 3 Konferensbidrag
• 3 Mer
  • 1 Ledare
  • 1 Brev
  • 1 Övriga bidrag

Forskningsresultat per år

Forskningsresultat per år

Sökresultat

• 2021

  Antibody Supervised Training of a Deep Learning Based Algorithm for Leukocyte Segmentation in Papillary Thyroid Carcinoma

  Stenman, S., Bychkov, D., Kücükel, H., Linder, N., Haglund, C., Arola, J. & Lundin, J., feb 2021, I: IEEE Journal of Biomedical and Health Informatics. 25, 2, s. 422 - 428 7 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Deep learning identifies morphological features in breast cancer predictive of cancer ERBB2 status and trastuzumab treatment efficacy

  Bychkov, D., Linder, N., Tiulpin, A., Kücükel, H., Lundin, M., Nordling, S., Sihto, H., Isola, J., Lehtimäki, T., Kellokumpu-Lehtinen, P-L., von Smitten, K., Joensuu, H. & Lundin, J., 17 feb 2021, I: Scientific Reports. 11, 1, 10 s., 4037.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Metastatic uveal melanoma managed with best supportive care

  Rantala, E. S., Hernberg, M. M., Lundin, M., Lundin, J. & Kivelä, T. T., 2 jan 2021, I: Acta Oncologica. 60, 1, s. 135–139 5 s.

  Forskningsoutput: Tidskriftsbidrag › Brev › Vetenskaplig

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• Point-of-Care Digital Cytology With Artificial Intelligence for Cervical Cancer Screening in a Resource-Limited Setting

  Holmström, O., Linder, N., Kaingu, H., Mbuuko, N., Mbete, J., Kinyua, F., Törnquist, S., Muinde, M., Krogerus, L., Lundin, M., Diwan, V. & Lundin, J., 17 mar 2021, I: JAMA Network Open. 4, 3, s. e211740-e211740 13 s., 211740.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• 2020

  A novel deep learning-based point-of-care diagnostic method for detecting Plasmodium falciparum with fluorescence digital microscopy

  Holmström, O., Stenman, S., Suutala, A., Moilanen, H., Kücükel, H., Ngasala, B., Mårtensson, A., Mhamilawa, L., Aydin-Schmidt, B., Lundin, M., Diwan, V., Linder, N. & Lundin, J., 17 nov 2020, I: PLoS One. 15, 11, 17 s., e0242355.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Artificial intelligence, diagnostic imaging and neglected tropical diseases: ethical implications

  Vaisman, A., Linder, N., Lundin, J., Orchanian-Cheff, A., Coulibal, J. T., Ephraim, R. K. D. & Bogoch, I. I., apr 2020, I: Bulletin of the World Health Organization. 98, 4, s. 288-289 2 s.

  Forskningsoutput: Tidskriftsbidrag › Ledare › Vetenskaplig › Peer review

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• Dataset for "Metastatic Uveal Melanoma Managed with Best Supportive Care"

  Rantala, E., Hernberg, M. M., Lundin, M., Lundin, J. & Kivelä, T., 28 aug 2020

  Forskningsoutput: Övriga bidrag › Peer review

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• Deep Learning Algorithms for Corneal Amyloid Deposition Quantitation in Familial Amyloidosis

  Kessel, K., Mattila, J., Linder, N., Kivelä, T. & Lundin, J., jan 2020, I: Ocular oncology and pathology. 6, 1, s. 58-65 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia

  Wedenoja, S., Yoshihara, M., Teder, H., Sariola, H., Gissler, M., Katayama, S., Wedenoja, J., Häkkinen, I. M. K., Ezer, S., Linder, N., Lundin, J., Skoog, T., Sahlin, E., Iwarsson, E., Pettersson, K., Kajantie, E., Mokkonen, M., Heinonen, S., Laivuori, H., Krjutskov, K. & 1 andra, Kere, J., sep 2020, I: EBioMedicine. 59, 13 s., 102872.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Machine-learning-driven biomarker discovery for the discrimination between allergic and irritant contact dermatitis

  Fortino, V., Wisgrill, L., Werner, P., Suomela, S., Linder, N., Jalonen, E., Suomalainen, A., Marwah, V., Kero, M., Pesonen, M., Lundin, J., Lauerma, A., Aalto-Korte, K., Greco, D., Alenius, H. & Fyhrquist, N., 29 dec 2020, I: Proceedings of the National Academy of Sciences of the United States of America. 117, 52, s. 33474-33485 12 s.

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• Osteoid Metaplasia in Femoral Artery Plaques Is Associated With the Clinical Severity of Lower Extremity Artery Disease in Men

  Laivuori, M., Tolva, J., Lokki, A. I., Linder, N., Lundin, J., Paakkanen, R., Albäck, A., Venermo, M., Mäyränpää, M. I., Lokki, M-L. & Sinisalo, J., 10 dec 2020, I: Frontiers in cardiovascular medicine. 7, 13 s., 594192.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• 2019

  Breast cancer outcome prediction with tumour tissue images and machine learning

  Turkki, R., Byckhov, D., Lundin, M., Isola, J., Nordling, S., Kovanen, P. E., Verrill, C., von Smitten, K., Joensuu, H., Lundin, J. & Linder, N., aug 2019, I: Breast Cancer Research and Treatment. 177, 1, s. 41-52 12 s.

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• Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient‐derived cancer cells

  Saeed, K., Ojamies, P., Pellinen, T., Eldfors, S., Turkki, R., Lundin, J., Järvinen, P., Nisén, H., Taari, K., af Hällström, T. M., Rannikko, A., Mirtti, T., Kallioniemi, O-P. & Östling, P., 15 mar 2019, I: International Journal of Cancer. 144, 6, s. 1356-1366 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Deep learning for detecting tumour-infiltrating lymphocytes in testicular germ cell tumours

  Linder, N., Taylor, J. C., Colling, R., Pell, R., Alveyn, E., Joseph, J., Protheroe, A., Lundin, M., Lundin, J. & Verrill, C., feb 2019, I: Journal of Clinical Pathology. 72, 2, s. 157-164 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Detection of breast cancer lymph node metastases in frozen sections with a point-of care low-cost microscope scanner

  Holmström, O., Linder, N., Moilanen, H., Suutala, A., Nordling, S., Ståhls, A., Lundin, M., Diwan, V. & Lundin, J., 19 mar 2019, I: PLoS One. 14, 3, 15 s., 0208366.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Spa-RQ: an Image Analysis Tool to Visualise and Quantify Spatial Phenotypes Applied to Non-Small Cell Lung Cancer

  Bao, J., Walliander, M., Kovacs, F., Nagaraj, A. S., Hemmes, A., Sarhadi, V. K., Knuutila, S., Lundin, J., Horvath, P. & Verschuren, E. W., 26 nov 2019, I: Scientific Reports. 9, 11 s., 17613.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours (vol 245, pg 101, 2018)

  Narhi, K., Nagaraj, A. S., Parri, E., Turkki, R., van Duijn, P. W., Hemmes, A., Lahtela, J., Uotinen, V., Mayranpaa, M. I., Salmenkivi, K., Rasanen, J., Linder, N., Trapman, J., Rannikko, A., Kallioniemi, O., Af Hallstrom, T. M., Lundin, J., Sommergruber, W., Anders, S. & Verschuren, E. W., jan 2019, I: Journal of Pathology. 247, 1, s. 147-147 1 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
• 2018

  Deep learning based tissue analysis predicts outcome in colorectal cancer

  Bychkov, D., Linder, N., Turkki, R., Nordling, S., Kovanen, P. E., Verrill, C., Walliander, M., Lundin, M., Haglund, C. & Lundin, J., 21 feb 2018, I: Scientific Reports. 8, 11 s., 3395.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Establishment and high-throughput drug testing of multiple patient-derived cells from each renal cancer; intratumor heterogeneity of drug response and implications for precision medicine

  Saeed, K., Ojamies, P., Pellinen, T., Eldfors, S., Turkki, R., Lundin, J., Nisen, H., Järvinen, P., Taari, K., af Hallstrom, T., Rannikko, A., Mirtti, T., Kallioniemi, O. & Ostling, P., jul 2018, I: Cancer Research. 78, 13, 2 s.

  Forskningsoutput: Tidskriftsbidrag › Mötesabstrakt › Forskning › Peer review

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• Increased HSF1 expression predicts shorter disease-specific survival of prostate cancer patients following radical prostatectomy

  Björk, J. K., Ahonen, I., Mirtti, T., Erickson, A., Rannikko, A., Butzow, A., Nordling, S., Lundin, J., Lundin, M., Sistonen, L., Nees, M. & Akerfelt, M., 2018, I: Oncotarget. 9, 58, s. 31200-31213 14 s.

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• Spatial aspects of oncogenic signalling determine the response to combination therapy in slice explants from Kras-driven lung tumours

  Närhi, K., Nagaraj, A. S., Parri, E., Turkki, R., van Duijn, P. W., Hemmes, A., Lahtela, J., Uotinen, V., Mäyränpää, M. I., Salmenkivi, K., Räsänen, J., Linder, N., Trapman, J., Rannikko, A., Kallioniemi, O., Af Hällström, T. M., Lundin, J., Sommergruber, W., Anders, S. & Verschuren, E. W., maj 2018, I: Journal of Pathology. 245, 1, s. 101-113 13 s.

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• The prognostic significance of tall cells in papillary thyroid carcinoma: A case-control study

  Stenman, S., Siironen, P., Mustonen, H., Lundin, J., Haglund, C. & Arola, J., 2018, I: Tumor Biology. 40, 7, 7 s., 1010428318787720.

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• 2017

  A roadmap for the implementation of mHealth innovations for image-based diagnostic support in clinical and public-health settings: a focus on front-line health workers and health-system organizations

  Wallis, L., Hasselberg, M., Barkman, C., Bogoch, I., Broomhead, S., Dumont, G., Groenewald, J., Lundin, J., Bergendahl, J. N., Nyasulu, P., Olofsson, M., Weinehall, L. & Laflamme, L., 2017, I: Global health action. 10, 10 s., 1340254.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Deep learning for image-based diagnostic support: initial development of a system for acute burns

  Boissin, C., Fransen, J., Laflamme, L., Allorto, N., Wallis, L., Huss, F. & Lundin, J., nov 2017, I: European Journal of Public Health. 27, s. 436-436 1 s.

  Forskningsoutput: Tidskriftsbidrag › Mötesabstrakt › Forskning › Peer review

• Exploration of tissue morphologies in breast cancer samples using unsupervised machine learning

  Turkki, R., Bychkov, D., Linder, N., Isola, J., Joensuu, H. T. & Lundin, J., 1 jul 2017, I: Cancer Research. 77, 13 Supplement, s. 673 1 s.

  Forskningsoutput: Tidskriftsbidrag › Mötesabstrakt › Forskning › Peer review

• Medical mobile technologies - what is needed for a sustainable and scalable implementation on a global scale?

  Lundin, J. & Dumont, G., 2017, I: Global health action. 10, Suppl. 3, 4 s., 1344046.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Mobile phone and handheld microscopes for public health applications

  Bogoch, I. I., Lundin, J., Lo, N. C. & Andrews, J. R., 2 aug 2017, I: The Lancet Public Health. 2, 8, 1 s., 355.

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• Point-of-care mobile digital microscopy and deep learning for the detection of soil-transmitted helminths and Schistosoma haematobium

  Holmstrom, O., Linder, N., Ngasala, B., Martensson, A., Linder, E., Lundin, M., Moilanen, H., Suutala, A., Diwan, V. & Lundin, J., 2017, I: Global health action. 10, 9 s., 1337325.

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• Precision systems medicine in urological Tumors – Molecular profiling and functional testing

  Saeed, K., Ojamies, P., Pellinen, T., Rahkama, V., Eldfors, S., Paavolainen, L., Turkki, R., Horvath, P., Lundin, J., Nisén, H., af Hällström, T. M., Rannikko, A., Mirtti, T., Kallioniemi, O. & Östling, P., 17 okt 2017, I: Annals of Oncology. 28, Suppl 7, 1 s.

  Forskningsoutput: Tidskriftsbidrag › Konferensartikel › Vetenskaplig

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• Systems pathology by multiplexed immunohistochemistry and whole-slide digital image analysis

  Blom, S., Paavolainen, L., Bychkov, D., Turkki, R., Maki-Teeri, P., Hemmes, A., Valimaki, K., Lundin, J., Kallioniemi, O. & Pellinen, T., 14 nov 2017, I: Scientific Reports. 7, 13 s., 15580.

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• 2016

  Antibody-supervised deep learning for quantification of tumor-infiltrating immune cells in hematoxylin and eosin stained breast cancer samples

  Turkki, R., Linder, N., Kovanen, P. E., Pellinen, T. & Lundin, J., 1 sep 2016, I: Journal of pathology informatics. 7, 9 s., 38.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• A Smartphone App and Cloud-Based Consultation System for Burn Injury Emergency Care

  Wallis, L. A., Fleming, J., Hasselberg, M., Laflamme, L. & Lundin, J., 26 feb 2016, I: PLoS One. 11, 2, 19 s., 0147253.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus

  Taipale, K., Liikanen, I., Juhila, J., Turkki, R., Tahtinen, S., Kankainen, M., Vassilev, L., Ristimaki, A., Koski, A., Kanerva, A., Diaconu, I., Cerullo, V., Vaha-Koskela, M., Oksanen, M., Linder, N., Joensuu, T., Lundin, J. & Hemminki, A., jan 2016, I: Molecular therapy. 24, 1, s. 175-183 9 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

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• Deep learning for tissue microarray image-based outcome prediction in patients with colorectal cancer

  Bychkov, D., Turkki, R., Haglund, C., Linder, N. & Lundin, J., 2016, Medical Imaging 2016: Digital Pathology. Gurcan, M. N. & Madabhushi, A. (red.). SPIE - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, s. 979115 6 s. (Proceedings of SPIE; vol. 9791).

  Forskningsoutput: Kapitel i bok/rapport/konferenshandling › Konferensbidrag › Vetenskaplig › Peer review

• Identification of immune cell infiltration in hematoxylin-eosin stained breast cancer samples: Texture-based classification of tissue morphologies

  Turkki, R., Linder, N., Kovanen, P. E., Pellinen, T. & Lundin, J., 2016, MEDICAL IMAGING 2016: DIGITAL PATHOLOGY. Gurcan, MN. & Madabhushi, A. (red.). SPIE - INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING, 7 s. 979110. (Proceedings of SPIE; vol. 9791).

  Forskningsoutput: Kapitel i bok/rapport/konferenshandling › Konferensbidrag › Vetenskaplig › Peer review

• Immune cell profiling in CML bone marrow by multiplex IHC

  Bruck, O., Blom, S., Turkki, R., Kovanen, P., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., nov 2016, I: Annals of Oncology. 27, 1 s.

  Forskningsoutput: Tidskriftsbidrag › Mötesabstrakt › Forskning › Peer review

• Immune Cell Profiling in CML Bone Marrow By Multiplex Immunohistochemistry

  Oscar, B., Blom, S., Turkki, R., Kovanen, P. E., Ribeiro, A., Linder, N., Lundin, J., Kallioniemi, O., Pellinen, T. & Mustjoki, S., 2 dec 2016, I: Blood. 128, 22, 4 s.

  Forskningsoutput: Tidskriftsbidrag › Mötesabstrakt › Forskning › Peer review

• Loss of PTEN expression in ERG-negative prostate cancer predicts secondary therapies and leads to shorter disease-specific survival time after radical prostatectomy

  Lahdensuo, K., Erickson, A., Saarinen, I., Seikkula, H., Lundin, J., Lundin, M., Nordling, S., Butzow, A., Vasarainen, H., Bostrom, P. J., Taimen, P., Rannikko, A. & Mirtti, T., dec 2016, I: Modern Pathology. 29, 12, s. 1565-1574 10 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Phase I study with ONCOS-102 for the treatment of solid tumors - an evaluation of clinical response and exploratory analyses of immune markers

  Ranki, T., Pesonen, S., Hemminki, A., Partanen, K., Kairemo, K., Alanko, T., Lundin, J., Linder, N., Turkki, R., Ristimäki, A., Jaeger, E., Karbach, J., Wahle, C., Kankainen, M., Backman, C., von Euler, M., Haavisto, E., Hakonen, T., Heiskanen, R., Jaderberg, M. & 6 andra, Juhila, J., Priha, P., Suoranta, L., Vassilev, L., Vuolanto, A. & Joensuu, T., 15 mar 2016, I: Journal for Immunotherapy of Cancer. 4, 18 s., 17.

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• 2015

  Androgen receptor-interacting protein HSPBAP1 facilitates growth of prostate cancer cells in androgen-deficient conditions

  Saeed, K., Östling, P. K., Björkman, M., Mirtti, T., Alanen, K., Vesterinen, T., Sankila, A., Lundin, J., Lundin, M., Rannikko, A., Nordling, S., Mpindi, J-P., Kohonen, P., Iljin, K., Kallioniemi, O. & Rantala, J. K., 2015, I: International Journal of Cancer. 136, 11, s. 2535-2545 11 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Assessment of tumour viability in human lung cancer xenografts with texture-based image analysis

  Turkki, R., Linder, N., Holopainen, T., Wang, Y., Grote, A., Lundin, M., Alitalo, K. & Lundin, J., aug 2015, I: Journal of Clinical Pathology. 68, 8, s. 614-621 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Benefit of adjuvant interferon alfa-2b (IFN-alpha) therapy in melanoma patients with high serum MMP-8 levels

  Vihinen, P., Tervahartiala, T., Sorsa, T., Hansson, J., Bastholt, L., Aamdal, S., Stierner, U., Pyrhonen, S., Syrjanen, K., Lundin, J. & Hernberg, M., feb 2015, I: Cancer Immunology, Immunotherapy. 64, 2, s. 173-180 8 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Elevated Levels of StAR-Related Lipid Transfer Protein 3 Alter Cholesterol Balance and Adhesiveness of Breast Cancer Cells Potential Mechanisms Contributing to Progression of HER2-Positive Breast Cancers

  Vassilev, B., Sihto, H., Li, S., Holtta-Vuori, M., Ilola, J., Lundin, J., Isola, J., Kellokumpu-Lehtinen, P-L., Joensuu, H. & Ikonen, E., apr 2015, I: The American Journal of Pathology. 185, 4, s. 987-1000 14 s.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Exploring viewing behavior data from whole slide images to predict correctness of students' answers during practical exams in oral pathology

  Walkowski, S., Lundin, M., Szymas, J. & Lundin, J., 2015, I: Journal of pathology informatics. 6, 28.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• Immunological data from cancer patients treated with Ad5/3-E2F-Delta 24-GMCSF suggests utility for tumor immunotherapy

  Hemminki, O., Parviainen, S., Juhila, J., Turkki, R., Linder, N., Lundin, J., Kankainen, M., Ristimaki, A., Koski, A., Liikanen, I., Oksanen, M., Nettelbeck, D. M., Kairemo, K., Partanen, K., Joensuu, T., Kanerva, A. & Hemminki, A., 28 feb 2015, I: Oncotarget. 6, 6, s. 4467-4481 15 s.

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• Quantification of Estrogen Receptor-Alpha Expression in Human Breast Carcinomas With a Miniaturized, Low-Cost Digital Microscope: A Comparison with a High-End Whole Slide-Scanner: PLoS One

  Holmström, O., Linder, N., Lundin, M., Moilanen, H., Suutala, A., Turkki, R., Joensuu, H., Isola, J., Diwan, V. & Lundin, J., 2015, I: PLoS One. 10, 12, 16 s., 0144688.

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• Repeated intratumoral administration of ONCOS-102 leads to systemic antitumor CD8(+) T-cell response and robust cellular and transcriptional immune activation at tumor site in a patient with ovarian cancer

  Vassilev, L., Ranki, T., Joensuu, T., Jaeger, E., Karbach, J., Wahle, C., Partanen, K., Kairemo, K., Alanko, T., Turkki, R., Linder, N., Lundin, J., Ristimaki, A., Kankainen, M., Hemminki, A., Backman, C., Dienel, K., von Euler, M., Haavisto, E., Hakonen, T. & 5 andra, Juhila, J., Jaderberg, M., Priha, P., Vuolanto, A. & Pesonen, S., 2015, I: OncoImmunology. 4, 7, 5 s., 1017702.

  Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

• T-cell Subsets in Peripheral Blood and Tumors of Patients Treated With Oncolytic Adenoviruses

  Taipale, K., Liikanen, I., Juuso, J., Aila, K-K., Oksanen, M., Turkki, R., Linder, N., Lundin, J., Ristimäki, A., Kanerva, A., Koski, A., Joensuu, T., Vähä-Koskela, M. & Hemminki, A., maj 2015, I: Molecular therapy. 23, 5, s. 964-973 10 s.

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• 2014

  A Malaria Diagnostic Tool Based on Computer Vision Screening and Visualization of Plasmodium falciparum Candidate Areas in Digitized Blood Smears

  Linder, N., Turkki, R., Walliander, M., Martensson, A., Diwan, V., Rahtu, E., Pietikainen, M., Lundin, M. & Lundin, J., 21 aug 2014, I: PLoS One. 9, 8, 12 s., 104855.

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• Exploring the spatial dimension of estrogen and progesterone signaling: detection of nuclear labeling in lobular epithelial cells in normal mammary glands adjacent to breast cancer

  Grote, A., Abbas, M., Linder, N., Kreipe, H. H., Lundin, J. & Feuerhake, F., 19 dec 2014, I: Diagnostic Pathology. 9, Suppl 1, 13 s.

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