1991 …2019
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Publikationer 1991 2019

2019

Direct Measurement of Amorphous Solubility

Stukelj, J., Svanback, S., Agopov, M., Lobmann, K., Strachan, C. J., Rades, T. & Yliruusi, J., 4 jun 2019, I : Analytical Chemistry. 91, 11, s. 7411-7417 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Effect of headspace gas on nucleation of amorphous paracetamol

Palomäki, E. A. K., Yliruusi, J. K. & Ehlers, H., jun 2019, I : Journal of Drug Delivery Science and Technology. 51, s. 127-138 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Image-Based Investigation: Biorelevant Solubility of α and γ Indomethacin

Štukelj, J., Svanbäck, S., Kristl, J., Strachan, C. J. & Yliruusi, J., 19 mar 2019, I : Analytical Chemistry. 91, 6, s. 3997-4003 7 s.

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2018

3D printed UV light cured polydimethylsiloxane devices for drug delivery

Hollander, J., Hakala, R., Suominen, J., Moritz, N., Yliruusi, J. & Sandler, N., 15 jun 2018, I : International Journal of Pharmaceutics. 544, 2, s. 433-442 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Interdependence of particle properties and bulk powder behavior of indomethacin in quench-cooled molten two-phase solid dispersions

Semjonov, K., Salm, M., Lipiäinen, T., Kogermann, K., Lust, A., Laidmäe, I., Antikainen, O., Strachan, C. J., Ehlers, H., Yliruusi, J. & Heinämäki, J., 2018, I : International Journal of Pharmaceutics. 541, 1-2, s. 188-197 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Melt-electrospinning as a method to improve the dissolution and physical stability of a poorly water-soluble drug

Semjonov, K., Lust, A., Kogermann, K., Laidmäe, I., Maunu, S. L., Hirvonen, S-P., Yliruusi, J., Nurk, G., Lust, E. & Heinamäki, J., 30 aug 2018, I : European Journal of Pharmaceutical Sciences. 121, s. 260-268 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Time-Gated Raman Spectroscopy for Quantitative Determination of Solid-State Forms of Fluorescent Pharmaceuticals

Lipiäinen, T., Pessi, J., Movahedi, P., Koivistoinen, J., Kurki, L., Tenhunen, M., Yliruusi, J., Juppo, A. M., Heikkonen, J., Pahikkala, T. & Strachan, C. J., 3 apr 2018, I : Analytical Chemistry. 90, 7, s. 4832-4839 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2017

3D printed drug delivery devices: perspectives and technical challenges

Palo, M., Hollander, J., Suominen, J., Yliruusi, J. & Sandler, N., 2017, I : Expert Review of Medical Devices. 14, 9, s. 685-696 12 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Introducing a novel gravitation-based high-velocity compaction analysis method for pharmaceutical powders

Tanner, T., Antikainen, O., Ehlers, H. & Yliruusi, J., 30 jun 2017, I : International Journal of Pharmaceutics. 526, 1-2, s. 31-40 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Lyophilic matrix method for dissolution and release studies of nanoscale particles

Pessi, J., Svanbäck, S., Lassila, I., Haeggstrom, E. & Yliruusi, J., 25 okt 2017, I : Journal of Pharmaceutical and Biomedical Analysis. 145, s. 549-554 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Simultaneous Comparison of Two Roller Compaction Techniques and Two Particle Size Analysis Methods

Saarinen, T., Antikainen, O. & Yliruusi, J., nov 2017, I : AAPS PharmSciTech. 18, 8, s. 3198-3207 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Suberin Fatty Acids from Outer Birch Bark: Isolation and Physical Material Characterization

Heinämäki, J., Pirttimaa, M. M., Alakurtti, S., Pitkänen, H. P., Kanerva, H., Hulkko, J., Paaver, U., Aruväli, J., Yliruusi, J. & Kogermann, K., apr 2017, I : Journal of Natural Products. 80, 4, s. 916-924 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Development of a Novel Electrospun Nanofibrous Delivery System for Poorly Water-Soluble ß-Sitosterol

Paaver, U., Laidmäe, I., Almeida Santos, H., Yliruusi, J. K., Aruväli, J., Kogermann, K. & Heinämäki, J. T., aug 2016, I : Asian Journal of Pharmaceutical Sciences. 11, 4, s. 500–506 7 s.

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Development of Suberin Fatty Acids and Chloramphenicol-Loaded Antimicrobial Electrospun Nanofibrous Mats Intended for Wound Therapy

Tamm, I., Heinämäki, J., Laidmae, I., Rammo, L., Paaver, U., Ingebrigtsen, S. G., Skalko-Basnet, N., Halenius, A., Yliruusi, J., Pitkänen, P., Alakurtti, S. & Kogermann, K., mar 2016, I : Journal of Pharmaceutical Sciences. 105, 3, s. 1239-1247 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Device and method to produce nanofibers and constructs thereof

Salmi, A. H., Haeggström, E. O., Nieminen, H. J., Paulin, T. A., Rauhala, T. J. J., Yliruusi, J. K., Heinämäki, J. T., Laidmäe, I., Falk, K. & Veski, P., 29 sep 2016, Patentnr. WO 2016151191 A1, Prioritetsdatum 24 mar 2015

Forskningsoutput: Patent

Monitoring the recrystallisation of amorphous xylitol using Raman spectroscopy and wide-angle X-ray scattering

Palomäki, E., Ahvenainen, P., Ehlers, H., Svedström, K., Huotari, S. & Yliruusi, J., 7 maj 2016, I : International Journal of Pharmaceutics. 508, 1-2, s. 71-82 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Towards improved solubility of poorly water-soluble drugs: cryogenic co-grinding of piroxicam with carrier polymers

Penkina, A., Semjonov, K., Hakola, M., Vuorinen, S., Repo, T., Yliruusi, J., Aruväli, J., Kogermann, K., Veski, P. & Heinämäki, J., 3 mar 2016, I : Drug Development and Industrial Pharmacy. 42, 3, s. 378-388 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2015

Amorphous solid dispersions of piroxicam and Soluplus (R): Qualitative and quantitative analysis of piroxicam recrystallization during storage

Lust, A., Strachan, C. J., Veski, P., Aaltonen, J., Heinämäki, J., Yliruusi, J. & Kogermann, K., 30 maj 2015, I : International Journal of Pharmaceutics. 486, 1-2, s. 306-314 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Assessment of Recent Process Analytical Technology (PAT) Trends: A Multiauthor Review

Simon, L. L., Pataki, H., Marosi, G., Meemken, F., Hungerbuehler, K., Baiker, A., Tummala, S., Glennon, B., Kuentz, M., Steele, G., Kramer, H. J. M., Rydzak, J. W., Chen, Z., Morris, J., Kjell, F., Singh, R., Gani, R., Gernaey, K. V., Louhi-Kultanen, M., O'Reilly, J. & 26 andra, Sandler, N., Antikainen, O., Yliruusi, J., Frohberg, P., Ulrich, J., Braatz, R. D., Leyssens, T., von Stosch, M., Oliveira, R., Tan, R. B. H., Wu, H., Khan, M., O'Grady, D., Pandey, A., Westra, R., Delle-Case, E., Pape, D., Angelosante, D., Maret, Y., Steiger, O., Lenner, M., Abbou-Oucherif, K., Nagy, Z. K., Litster, J. D., Kamaraju, V. K. & Chiu, M-S., jan 2015, I : Organic Process Research and Development. 19, 1, s. 3-62 60 s.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

High-Speed Intrinsic Dissolution Rate in One Minute Using the Single-Particle Intrinsic Dissolution Rate Method

Svanbäck, S., Ehlers, H., Antikainen, O. & Yliruusi, J., 3 nov 2015, I : Analytical Chemistry. 87, 21, s. 11058-11064 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Non-destructive assessment of mechanical properties of microcrystalline cellulose compacts

Palomäki, E., Ehlers, H., Antikainen, O., Sandler, N. & Yliruusi, J., 30 nov 2015, I : International Journal of Pharmaceutics. 495, 2, s. 633-641 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Spectroscopic insight for tablet compression

Lakio, S., Ylinärä, H., Antikainen, O., Räikkönen, H. & Yliruusi, J., feb 2015, I : European Journal of Pharmaceutics and Biopharmaceutics. 90, s. 16-21 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Suberin fatty acids isolated from outer birch bark improve moisture barrier properties of cellulose ether films intended for tablet coatings

Heinämäki, J., Halenius, A., Paavo, M., Alakurtti, S., Pitkänen, P., Pirttimaa, M., Paaver, U., Kirsimäe, K., Kogermann, K. & Yliruusi, J., 15 jul 2015, I : International Journal of Pharmaceutics. 489, 1-2, s. 91-99 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2014

Fast Tablet Tensile Strength Prediction Based on Non-Invasive Analytics

Halenius, A., Lakio, S., Antikainen, O., Hatara, J. & Yliruusi, J., jun 2014, I : AAPS PharmSciTech. 15, 3, s. 781-791 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Microfluidics-assisted engineering of polymeric microcapsules with high encapsulation efficiency for protein drug delivery

Pessi, J., Santos, H. A., Miroshnyk, I., Yliruusi, J., Weitz, D. & Mirza, S., jun 2014, I : International Journal of Pharmaceutics. 472 , 1–2, s. 82–87 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

On-line monitoring of fluid bed granulation by photometric imaging

Soppela, I., Antikainen, O., Sandler, N. & Yliruusi, J., nov 2014, I : European Journal of Pharmaceutics and Biopharmaceutics. 88, 3, s. 879-885 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Optical microscopy as a comparative analytical technique for single-particle dissolution studies

Svanback, S., Ehlers, H. & Yliruusi, J., 20 jul 2014, I : International Journal of Pharmaceutics. 469, 1, s. 10-16 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2013

Challenges in Detecting Magnesium Stearate Distribution in Tablets

Lakio, S., Vajna, B., Farkas, I., Salokangas, H., Marosi, G. & Yliruusi, J., 2013, I : AAPS PharmSciTech. 14, 1, s. 435-444

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Direct Compression of Cellulose and Lignin Isolated by a New Catalytic Treatment

Penkina, A., Antikainen, O., Hakola, M., Vuorinen, S., Repo, T., Yliruusi, J., Veski, P., Kogermann, K. & Heinämäki, J., sep 2013, I : AAPS PharmSciTech. 14, 3, s. 1129-1136 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Diversity in Itraconazole Cocrystals with Aliphatic Dicarboxylic Acids of Varying Chain Length

Shevchenko, A., Miroshnyk, I., Pietila, L-O., Haarala, J., Salmia, J., Sinervo, K., Mirza, S., van Veen, B., Kolehmainen, E., Nonappa, M. & Yliruusi, J., nov 2013, I : Crystal Growth & Design. 13, 11, s. 4877-4884 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

From acacia honey monosaccharide content to a new external binary plasticizer applicable in aqueous whey protein films

Soininen, J. T., Heinämäki, J. & Yliruusi, J., 2013, I : Food and Bioproducts Processing. 91, 4, s. 440-446 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects

Palttala, I., Heinämäki, J., Honkanen, O., Suominen, R., Antikainen, O., Hirvonen, J. & Yliruusi, J., mar 2013, I : Drug Development and Industrial Pharmacy. 39, 3, s. 489-498 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2012

A new cocrystal and salts of itraconazole: comparison of solid-state properties, stability and dissolution behavior

Shevchenko, A., Bimbo, L. M., Miroshnyk, I., Haarala, J., Jelínková, K., Syrjänen, K., van Veen, B., Kiesvaara, J., A. Santos, H. & Yliruusi, J., 2012, I : International Journal of Pharmaceutics. 436, 1-2, s. 403-409 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effect of polyethyleneglycol on coenzyme Q10 bioavailability from nanosystems in vitro

Karlina, M. V., Kosman, V. M., Pozharitskaya, O. N., Shikov, A. N., Makarov, V. G., Heinämäki, J., Yliruusi, J. & Hiltunen, R., 2012, I : Pharmaceutical Chemistry Journal. 46, 4, s. 241-244 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Particle size and packing characterization by diffuse light transmission

Ehlers, H., Heinämäki, J. & Yliruusi, J., okt 2012, I : Particuology. 10, 5, s. 619-627 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Solid-state properties of softwood lignin and cellulose isolated by a new acid precipitation method

Penkina, A., Hakola, M., Paaver, U., Vuorinen, S., Kirsimäe, K., Kogermann, K., Veski, P., Yliruusi, J., Repo, T. & Heinämäki, J., 1 dec 2012, I : International Journal of Biological Macromolecules. 51, 5, s. 939-945 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2011

3D-Simulation of internal tablet strength during tableting

Siiriä, S-M., Antikainen, O., Heinämäki, J. & Yliruusi, J., 2011, I : AAPS PharmSciTech. 12, 2, s. 593-603 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Coupling Polymorphism/Solvatomorphism and Physical Stability Evaluation with Early Salt Synthesis Optimization of an Investigational Drug

Shevchenko, A., Din Belle, D., Tiittanen, S., Karjalainen, A., Tolvanen, A., Tanninen, V-P., Haarala, J., Mäkelä, M., Yliruusi, J. & Miroshnyk, I., 26 apr 2011, I : Organic Process Research and Development. 15, 3, s. 666-672

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

DEM simulation of influence of parameters on energy and degree of mixing

Siiriä, S. & Yliruusi, J., aug 2011, I : Particuology. 9, 4, s. 406-413 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effects of moisture on tablet compression of chitin

García Mir, V., Heinämäki, J., Antikainen, O., Iraizoz Colartea, A., Airaksinen, S., Karjalainen, M., Bilbao Revoredo, O., Maria Nieto, O. & Yliruusi, J., 2011, I : Carbohydrate Polymers. 86, 2, s. 477-483

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effects of spray drying on physicochemical properties of chitosan acid salts

Fernández Cervera, M., Heinämäki, J., de la Paz, N., López, O., Maunu, S. L., Virtanen, T., Hatanpää, T., Antikainen, O., Nogueira, A., Fundora, J. & Yliruusi, J., 2011, I : AAPS PharmSciTech. 12, 2, s. 637-649 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Rapid particle size measurement using 3D surface imaging

Soppela, I., Airaksinen, S., Hatara, J., Räikkönen, H., Antikainen, O., Yliruusi, J. & Sandler, N., apr 2011, I : AAPS PharmSciTech. 12, 2, s. 476-484

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Real-time image-based investigation of spheronization and drying phenomena using different pellet formulations

Burggraeve, A., Sandler, N., Heinämäki, J., Räikkönen, H., Remon, J. P., Vervaet, C., DeBeer, T. & Yliruusi, J., 2011, I : European Journal of Pharmaceutical Sciences. 44, 5, s. 635-642 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2010

Application of Crustacean Chitin as a Co-diluent in Direct Compression of Tablets

Garcia Mir, V., Heinämäki, J., Antikainen, O., Sandler, N., Bilbao Revoredo, O., Iraizoz Colarte, A., Maria Nieto, O. & Yliruusi, J., 2010, I : AAPS PharmSciTech. 11, s. 409-415 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Colorful drying

Lakio, S., Heinämäki, J. & Yliruusi, J., 2010, I : AAPS PharmSciTech. 11, 1, s. 46-53

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review