Forskningsresultat per år
Forskningsresultat per år
Personlig profil
Information om forskning och undervisning
Our group is interested in how neuronal diversity is generated during embryonic development. In particular, we study the mechanisms of intercellular communication and gene regulation, which control neuronal differentiation in a distinct region of the vertebrate brain - the midbrain.
The midbrain contains neurons, such as dopaminergic and GABAergic neurons, which control several aspects of behavior, are involved in psychiatric disease and are targets of medical treatments as well as drugs of abuse. However, their molecular diversity and regulation of their development from neuroepithelial stem cells are poorly understood. We are addressing these questions using a combination of genetic and molecular approaches.
Vetenskapsgrenar
- 1184 Genetik, utvecklingsbiologi, fysiologi
- 3112 Neurovetenskaper
Internationellt och inhemskt samarbete
Publikationer och projekt inom de senaste fem åren.
Publikationer
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ADHD-like behaviors caused by inactivation of a transcription factor controlling the balance of inhibitory and excitatory neuron development in the mouse anterior brainstem
Morello, F., Voikar, V., Parkkinen, P., Panhelainen, A., Rosenholm, M., Makkonen, A., Rantamäki, T., Piepponen, P., Aitta-aho, T. & Partanen, J., 21 okt 2020, I : Translational Psychiatry. 10, 1, 15 s., 357.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil -
Kainate receptors regulate development of glutamatergic synaptic circuitry in the rodent amygdala
Ryazantseva, M., Englund, J., Shintyapina, A., Huupponen, J., Shteinikov, V., Pitkänen, A., Partanen, J. M. & Lauri, S. E., 23 mar 2020, I : eLife. 9, 25 s., 52798.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil -
Molecular Fingerprint and Developmental Regulation of the Tegmental GABAergic and Glutamatergic Neurons Derived from the Anterior Hindbrain
Morello, F., Borshagovski, D., Survila, M., Tikker, L., Sadik-Ogli, S., Kirjavainen, A., Estartús, N., Knaapi, L., Lahti, L., Törönen, P., Mazutis, L., Delogu, A., Salminen, M., Achim, K. & Partanen, J., 13 okt 2020, I : Cell Reports. 33, 2, 26 s., 108268.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil -
Crosstalk of Intercellular Signaling Pathways in the Generation of Midbrain Dopaminergic Neurons In Vivo and from Stem Cells
Brodski, C., Blaess, S., Partanen, J. & Prakash, N., 15 jan 2019, I : Journal of Developmental Biology. 7, 1, 34 s., 3.Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review
Öppen tillgångFil -
A complex genomic locus drives mtDNA replicase POLG expression to its disease-related nervous system regions
Nikkanen, J., Landoni, J. C., Balboa, D., Haugas, M., Partanen, J., Paetau, A., Isohanni, P., Brilhante, V. & Suomalainen, A., jan 2018, I : EMBO molecular medicine. 10, 1, s. 13-21 9 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil
Priser
Aktiviteter
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Examination of doctoral dissertation Jokinen
Juha Partanen (Förhandsgranskare)
2015Aktivitet: Examinationstyper › Förhandsgranskare av doktorsavhandling
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Examination of doctoral dissertation Zarkada
Juha Partanen (Förhandsgranskare)
2014Aktivitet: Examinationstyper › Förhandsgranskare av doktorsavhandling
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Examination of doctoral dissertation Hakanen
Juha Partanen (Förhandsgranskare)
2014Aktivitet: Examinationstyper › Förhandsgranskare av doktorsavhandling
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Examination of doctoral dissertation Fang
Juha Partanen (Förhandsgranskare)
2013Aktivitet: Examinationstyper › Förhandsgranskare av doktorsavhandling
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Suomen kehitysbiologian seura (Extern organisation)
Juha Partanen (Ordförande)
2013 → 2015Aktivitet: Medlemskapstyper › Medlemskap eller annan roll i organ inom privat företag/organisation