Foto av Kristiina Mäkinen

Kristiina Mäkinen, Docent, university lecturer

  • PL 56 (Viikinkaari 9)

    00014

    Finland

  • Viikinkaari 1, Biocentre 3

    00790 Helsinki

    Finland

19952020

Forskningsoutput per år

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Personlig profil

Information om forskning och undervisning

Research

Plant health is an increasingly important issue as sufficient food security is endangered by the global climate change and growing population of the world. The research in the group focuses on the molecular mechanisms underlying Potato virus A (PVA) infection. PVA is a member of genus Potyvirus, which is economically the most devastating group of plant RNA viruses. Understanding the different stages of virus infection is a prerequisite for being able to prevent infections. The research in the group is carried out with the advanced techniques of biochemistry, and molecular and cell biology. The aims of  our research are:

 1) to produce novel information of the various stages of the virus multiplication cycle (protein synthesis, RNA replication, virus movement, encapsidation), and how these functions are localized and coordinated within the infected cells.

2) to tackle the disease problem caused by the genus Potyvirus, which is economically the most devastating group of plant viruses. Host factors involved in viral multiplication represent potential targets for virus control. Their identification and functional characterization is one of the major frontiers in virus research.

3) to exploit viruses as gene vectors, viral regulatory sequences as valuable elements in plant expression vectors and virus particles in nanobiotechnology applications.

Teaching

My teaching consists of basic lecture and laboratory courses in biochemistry and gene technology. I have been an organizer and teacher on post graduate courses on plant virology, heterologous protein production in plants and protein interactions and biochemical analyses. I have supervised several MSc and PhD students.

Vetenskapsgrenar

  • 1183 Växtbiologi, mikrobiologi, virologi

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer

Insights into the Functions of eIF4E-Binding Motif of VPg in Potato Virus A Infection

Saha, S. & Makinen, K., feb 2020, I : Viruses. 12, 2, 22 s., 197.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Dynamics of Protein Accumulation from the 3 ' End of Viral RNA Are Different from Those in the Rest of the Genome in Potato Virus A Infection

Saha, S., Hafren, A. & Makinen, K., okt 2019, I : Journal of Virology. 93, 19, 18 s., ARTN e00721-19.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Introduction to Special Issue of Molecular Plant Pathology - "Extracellular and intracellular perception of plant viruses"

Aranda, M. A., Makinen, K. & Verchot, J., sep 2019, I : Molecular Plant Pathology. 20, 9, s. 1183-1184 2 s.

Forskningsoutput: TidskriftsbidragLedareVetenskaplig

Öppen tillgång
Fil

Molecular Plant Pathology: Special Issue of Molecular Plant Pathology - “Extracellular and intracellular perception of plant viruses”.

Aranda, M. (red.), Mäkinen, K. (red.) & Verchot, J. (red.), sep 2019, John Wiley & Sons Ltd.

Forskningsoutput: Bok/rapportAntologi eller special utgåvaVetenskaplig

Öppen tillgång

Plant susceptibility genes as a source for potyvirus resistance.

Mäkinen, K., 7 dec 2019, I : Annals of Applied Biology.

Forskningsoutput: TidskriftsbidragÖversiktsartikelVetenskapligPeer review

Projekter

Aktiviteter

Federation of European Biochemical Societies - Advanced Courses Committee (Extern organisation)

Kristiina Mäkinen (Styrelsemedlem)
20202023

Aktivitet: MedlemskapstyperMedlemskap eller annan role i inhemsk/internationell kommitté, råd, styrelse

International Advances in Plant Virology 2019

Kristiina Mäkinen (Talare: Inledningsanförande (keynote))
29 okt 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Molecular Plant Pathology (Tidskrift)

Miguel Aranda (Redaktör), Kristiina Mäkinen (Redaktör), Jeanmarie Verchot (Redaktör)
sep 2019

Aktivitet: Typer för peer review av output och redaktionsarbeteRedaktör för serie

18th Congress of International-Society-for-Molecular-Plant-Microbe-Interactions (IS-MPMI) - Satellite meeting: Extracellular and Intracellular Perception of Viruses

Kristiina Mäkinen (Medlem i organisationskommitté)
14 jul 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Plant Gene Editing panel discussionGenome editing for plant improvement – prospects and challenges

Kristiina Mäkinen (Medlem i organisationskommitté)
11 sep 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium