Foto på Kristiina Mäkinen
  • PL 56 (Viikinkaari 9)

    00014

    Finland

  • Viikinkaari 1, Biocentre 3

    00790 Helsinki

    Finland

19952019
Om du gjort några ändringar i Pure kommer de visas här snart.

Personlig profil

Information om forskning och undervisning

Research

Plant health is an increasingly important issue as sufficient food security is endangered by the global climate change and growing population of the world. The research in the group focuses on the molecular mechanisms underlying Potato virus A (PVA) infection. PVA is a member of genus Potyvirus, which is economically the most devastating group of plant RNA viruses. Understanding the different stages of virus infection is a prerequisite for being able to prevent infections. The research in the group is carried out with the advanced techniques of biochemistry, and molecular and cell biology. The aims of  our research are:

 1) to produce novel information of the various stages of the virus multiplication cycle (protein synthesis, RNA replication, virus movement, encapsidation), and how these functions are localized and coordinated within the infected cells.

2) to tackle the disease problem caused by the genus Potyvirus, which is economically the most devastating group of plant viruses. Host factors involved in viral multiplication represent potential targets for virus control. Their identification and functional characterization is one of the major frontiers in virus research.

3) to exploit viruses as gene vectors, viral regulatory sequences as valuable elements in plant expression vectors and virus particles in nanobiotechnology applications.

Teaching

My teaching consists of basic lecture and laboratory courses in biochemistry and gene technology. I have been an organizer and teacher on post graduate courses on plant virology, heterologous protein production in plants and protein interactions and biochemical analyses. I have supervised several MSc and PhD students.

Keywords

  • 1183 Växtbiologi, mikrobiologi, virologi

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer 1995 2019

  • 44 Artikel
  • 5 Kapitel
  • 5 Översiktsartikel
  • 1 Antologi eller special utgåva

Molecular insights into the function of the viral RNA silencing suppressor HCPro

Ivanov, K., Eskelin, K. J., Bašić, M., De, S., Lohmus, A., Varjosalo, M. T. & Mäkinen, K. M., 2016, I : Plant Journal. 85, 1, s. 30-45 16 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Formation of Potato virus A-induced RNA granules and viral translation are interrelated processes required for optimal virus accumulation

Hafren, A. J., Lohmus, A. & Mäkinen, K. M., 7 dec 2015, I : PLoS Pathogens. 11, 12, 28 s., e1005314.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

HSP70 and Its Cochaperone CPIP Promote Potyvirus Infection in Nicotiana benthamiana by Regulating Viral Coat Protein Functions

Hafren, A., Hofius, D., Rönnholm, G., Sonnewald, U. & Mäkinen, K., 2010, I : Plant Cell. 22, s. 523-535 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Introduction to Special Issue of Molecular Plant Pathology - “Extracellular and intracellular perception of plant viruses”.

Aranda, M., Mäkinen, K. & Verchot, J., 2 jun 2019, (!!Accepted/In press)

Forskningsoutput: Bok/rapportAntologi eller special utgåvaVetenskaplig

Öppen tillgång
Fil

Projekter 2007 2018

Aktiviteter 1999 2019

Molecular Plant Pathology (Tidskrift)

Kristiina Mäkinen (Redaktör)
1 jan 201531 dec 2017

Aktivitet: Typer för peer review av output och redaktionsarbeteRedaktör för vetenskaplig tidskrift

Doctoral Programme in Plant Sciences (Extern organisation)

Kristiina Mäkinen (Styrelsemedlem)
1 jan 201431 dec 2017

Aktivitet: MedlemskapstyperMedlemskap eller annan role i inhemsk/internationell kommitté, råd, styrelse

Societas biochemica, biophysica et microbiologica Fenniae eli "Biobio-seura" (Extern organisation)

Kristiina Mäkinen (Styrelsemedlem)
2010 → …

Aktivitet: MedlemskapstyperMedlemskap eller annan role i inhemsk/internationell kommitté, råd, styrelse

ScanVir2019 conference

Kristiina Mäkinen (Närvarande)
5 jun 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangPublic Talks

Production of heterologous proteins and metabolites in plants

Karen Sims-Huopaniemi (Medlem i organisationskommitté), Kristiina Mäkinen (Ordförande i organisationskommitté), Teemu Teeri (Ordförande i organisationskommitté)
6 maj 201910 maj 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium