Forskningsresultat per år
Forskningsresultat per år
Personlig profil
Forskningsintressen
Maciej Maurycy Lalowski works at the Medicum, Department of Biochemistry and Developmental Biology, Meilahti Clinical Proteomics Core Facility, HiLIFE, University of Helsinki. Maciej does research in Proteomics, Neurodegeneration and Mass Spectrometry Imaging. The current research projects relate to Alzheimer's Disease, Mood Disorders, Neuronal Ceroid Lipofuscinosis and Schizophrenia.
Utbildning information
MSc degree (1991), graduated with distinction/Faculty of Biology, University of Warsaw, Poland, scope biochemistry
1991-1992: Postgraduate studies, graduated with distinction
Faculty of Geography, Institute of Developing Countries, University of Warsaw
PhD degree (1997), graduated with distinction
Polish Academy of Sciences, Warsaw-Poland /joint research at NYU Medical Center, Dept. of Pathology, NYC, USA (1992-1996)
Docent (2011): University of Helsinki, Faculty of Medicine, scope medical biochemistry
Doctor habilitated (doktor habilitowany) (2021) Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan
Title: "Systematic studies on protein interactions and affected disease pathways underlying neuronal ceroid lipofuscinosis" (15.07.2021)
Utbildning / akademisk kvalifikation
Biological sciences, Doctor of Science (Doctor habilitated), Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan
20 nov. 2020 → 15 juli 2021
Tilldelningsdatum: 15 juli 2021
Alzheimer's Disease/aging, Doctor of Philosophy, Medical Research Center, Polish Academy of Sciences
1 mars 1992 → 1 dec. 1997
Tilldelningsdatum: 1 dec. 1997
Externa befattningar
Visiting professor, Adam Mickiewicz University, Institute of Molecular Biology and Biotechnology, Department of Gene Expression
1 nov. 2022 → …
Adjunct, Institute of Bioorganic Chemistry, Polish Academy of Science, Poznan-Poland
3 aug. 2020 → 31 juli 2021
Vetenskapsgrenar
- 3111 Biomedicinska vetenskaper
- 1182 Biokemi, cell- och molekylärbiologi
- 3112 Neurovetenskaper
- 318 Medicinsk bioteknologi
Internationellt och inhemskt samarbete
Publikationer och projekt inom de senaste fem åren.
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Altered acylcarnitine metabolism and inflexible mitochondrial fuel utilization characterize the loss of neonatal myocardial regeneration capacity
Kankuri, E., Finckenberg, P., Leinonen, J., Tarkia, M., Björk, S., Purhonen, J., Kallijärvi, J., Kankainen, M., Soliymani, R., Łałowski, M. & Mervaala, E., apr. 2023, I: Experimental & Molecular Medicine. 55, 4, s. 806–817 12 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil -
Ketogenic diet changes microglial morphology and the hippocampal lipidomic profile differently in stress susceptible versus resistant male mice upon repeated social defeat.
González Ibáñez, F., Halvorson, T., Sharma, K., McKee, C., Carrier, M., Picard, K., Vernoux, N., Bisht, K., Deslauriers, J., Lalowski, M. & Tremblay, M-È., nov. 2023, I: Brain, Behavior, and Immunity. 114, 23, s. 383-406 24 s.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
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Minocycline treatment improves cognitive and functional plasticity in a preclinical mouse model of major depressive disorder
Poggini, S., Banqueri Lopez, M., Ciano Albanese, N., Golia, M. T., González Ibáñez, F., Limatola, C., Fuhrmann, M., Lalowski, M., Tremblay, M-E., Maggi, L., Kaminska, B. & Branchi, I., 12 mars 2023, I: Behavioural Brain Research. 441, 114295, 10 s., 114295.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
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The structure and function of YTHDF epitranscriptomic m6A readers.
Sikorski, V., Selberg, S., Lalowski, M., Karelson, M. & Kankuri, E., 2023, I: Trends in Pharmacological Sciences. 44, 6, s. 335-353 19 s.Forskningsoutput: Tidskriftsbidrag › Översiktsartikel › Peer review
Öppen tillgångFil -
Integrative Organelle-Based Functional Proteomics: In Silico Prediction of Impaired Functional Annotations in SACS KO Cell Model
Morani, F., Doccini, S., Galatolo, D., Pezzini, F., Soliymani, R., Simonati, A., Lalowski, M., Gemignani, F. & Santorelli, F. M., aug. 2022, I: Biomolecules. 12, 8, 15 s., 1024.Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review
Öppen tillgångFil
Projekter
- 4 Slutfört
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MicroSynDep: Microglial control of synaptic function in stress response and vulnerability to depression
01/10/2018 → 31/10/2022
Projekt: Forskningsprojekt
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SZ_TEST: Towards Early Molecular Diagnostics of Schizophrenia
01/01/2017 → 31/12/2020
Projekt: Forskningsprojekt
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H2020 RISE project SZ_TEST
Lindholm, D. B., Lalowski, M., Vaheri, A., Tienari, P. & Korhonen, L.
01/01/2017 → 31/12/2020
Projekt: Forskningsprojekt
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Prop-AD: PROP-AD: Propagation behaviour of peripheral amyloid-β towards brain structures: effects of the blood-brain barrier.
01/10/2016 → 31/08/2019
Projekt: Forskningsprojekt
Aktiviteter
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Regression plane concept for analysing continuous cellular processes with machine learning
Maciej Lalowski (Medlem i avhandlingskommitté)
1 apr. 2021 → 31 dec. 2025Aktivitet: Examinationstyper › Medlem i doktorsavhandlingskommitté
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Spring Proteomics Highlights
Maciej Lalowski (Talare: Ordförande)
14 apr. 2021Aktivitet: Typer för deltagande i eller organisering av evenemang › Arrangemang av och deltagande i konferens/workshop/kurs/seminarium
Fil -
Platelet-derived extracellular vesicle subpopulations in health and disease
Maciej Lalowski (Medlem i avhandlingskommitté)
1 jan. 2021 → 31 dec. 2025Aktivitet: Examinationstyper › Medlem i doktorsavhandlingskommitté
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Diagnostic and prognostic role of expressed KRAS and BRAF mutations in MAPK/ERK-driven cancers
Maciej Lalowski (Annan roll (beskriv i "Relationsbeskrivning")), Jakob Stenman (Handledare), Arto Orpana (Bihandledare), Tho Huu Ho (Handledare), Ulf Gunarsson (Opponent), Klaus Elenius (Förhandsgranskare) & Markus Mäkinen (Förhandsgranskare)
21 juni 2021Aktivitet: Examinationstyper › Förhandsgranskare av doktorsavhandling
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Federation of European Biochemical Societies (Extern organisation)
Maciej Lalowski (Styrelsemedlem)
1 jan. 2020 → 31 dec. 2024Aktivitet: Medlemskapstyper › Medlemskap eller annan roll i inhemskt/internationellt offentligt organ
Tidningsurklipp
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Researchers have found a promising therapy for cardiac regeneration
Maciej Lalowski & Esko Kankuri
30/06/2020
5 objekt av Mediabevakning
Press/media: !!Press / Media
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A potential treatment for cardiac regeneration
Maciej Lalowski & Esko Kankuri
30/06/2020
3 objekt av Mediabevakning
Press/media: !!Press / Media
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Researchers use 'multiomics' approach to study newborn mouse heart
Maciej Lalowski & Esko Kankuri
04/06/2018
1 objekt av Mediabevakning
Press/media: !!Press / Media
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'Multiomics' and the newborn mouse heart
Maciej Lalowski & Esko Kankuri
01/06/2018 → 04/06/2018
3 objekt av Mediabevakning
Press/media: !!Press / Media
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'Multiomics' and the newborn mouse heart - New insights into the development of heart disease therapeutics
Maciej Lalowski, Päivi Lakkisto, Esko Kankuri & Marc Baumann
01/06/2018
1 objekt av Mediabevakning
Press/media: !!Press / Media