20112020

Forskningsoutput per år

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Publikationer

2020

Age-associated changes in the immune system may influence the response to anti-PD1 therapy in metastatic melanoma patients

Kasanen, H., Hernberg, M., Mäkelä, S., Brück, O., Juteau, S., Kohtamäki, L., Ilander, M., Mustjoki, S. & Kreutzman, A., 8 feb 2020, I : Cancer Immunology, Immunotherapy. 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival

Brück, O., Dufva, O., Hohtari, H., Blom, S., Turkki, R., Ilander, M., Kovanen, P., Pallaud, C., Ramos, P. M., Lähteenmäki, H., Välimäki, K., El Missiry, M., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 28 jan 2020, I : Blood advances. 4, 2, s. 274-286 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Plasma proteomics of biomarkers for inflammation or cancer cannot predict relapse in chronic myeloid leukaemia patients stopping tyrosine kinase inhibitor therapy

Soderlund, S., Persson, I., Ilanderd, M., Guilhot, J., Hjorth-Hansen, H., Koskenvesa, P., Richter, J., Saussele, S., Mustjoki, S. & Olsson-Strömberg, U., mar 2020, I : Leukemia Research. 90, 7 s., 106310.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2019

Novel TMEM173 Mutation and the Role of Disease Modifying Alleles

Keskitalo, S., Haapaniemi, E., Einarsdottir, E., Rajamäki, K., Heikkilä, H., Ilander, M., Pöyhönen, M., Morgunova, E., Hokynar, K., Lagström, S., Kivirikko, S., Mustjoki, S., Eklund, K., Saarela, J., Kere, J., Seppänen, M. R. J., Ranki, A., Hannula-Jouppi, K. & Varjosalo, M., 5 dec 2019, I : Frontiers in Immunology. 10, 17 s., 2770.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Pharmacological reactivation of MYC-dependent apoptosis induces susceptibility to anti-PD-1 immunotherapy

Haikala, H. M., Anttila, J. M., Marques, E., Raatikainen, T., Ilander, M., Hakanen, H., Ala-Hongisto, H., Savelius, M., Balboa, D., Von Eyss, B., Eskelinen, V., Munne, P., Nieminen, A. I., Otonkoski, T., Schüler, J., Laajala, T. D., Aittokallio, T., Sihto, H., Mattson, J., Heikkilä, P. & 7 andra, Leidenius, M., Joensuu, H., Mustjoki, S., Kovanen, P., Eilers, M., Leverson, J. D. & Klefström, J., 6 feb 2019, I : Nature Communications. 10, 17 s., 620.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2018

ADA2 deficiency: Clonal lymphoproliferation in a subset of patients

Trotta, L., Martelius, T., Siitonen, T., Hautala, T., Hämäläinen, S., Juntti, H., Taskinen, M., Ilander, M., Andersson, E. I., Zavialov, A., Kaustio, M., Keski-Filppula, R., Hershfield, M., Mustjoki, S., Tapiainen, T., Seppänen, M. & Saarela, J., apr 2018, I : Journal of Allergy and Clinical Immunology. 141, 4, s. 1534-+ 12 s.

Forskningsoutput: TidskriftsbidragBrevVetenskapligPeer review

Divergent roles for antigenic drive in the aetiology of primary versus dasatinib-associated CD8(+) TCR-Vβ(+) expansions

Lissina, A., McLaren, J. E., Ilander, M., Andersson, E. I., Lewis, C. S., Clement, M., Herman, A., Ladell, K., Llewellyn-Lacey, S., Miners, K. L., Gostick, E., Melenhorst, J. J., Barrett, A. J., Price, D. A., Mustjoki, S. & Wooldridge, L., 7 feb 2018, I : Scientific Reports. 8, 12 s., 2534.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Genome-Scale CRISPR Screens Identify Essential Genes for Sensitivity to Natural Killer Cells in Hematological Malignancies

Dufva, O., Klievink, J., Saeed, K., Kankainen, M., Ilander, M., Hannunen, T., Lagstrom, S., Ellonen, P., Lee, D. A. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Immune cell phenotype and functional defects in Netherton syndrome

Eränkö, E., Ilander, M., Tuomiranta, M., Mäkitie, A., Lassila, T., Kreutzman, A., Klemetti, P., Mustjoki, S., Hannula-Jouppi, K. & Ranki, A., 26 nov 2018, I : Orphanet journal of rare diseases. 13, 10 s., 213.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Quantitative Multiplex Immunohistochemistry Identifies Immunosuppression in the AML Bone Marrow and NK-Cells As Prognostic Biomarker in Intermediate-Risk Patients

Bruck, O., Dufva, O., Blom, S., Turkki, R., Ilander, M., Siitonen, S. M., Kovanen, P., Pallaud, C., Ramos, P. M., Lahteenmaki, H., Valimaki, K., Ribeiro, A., Kallioniemi, O., Porkka, K., Pellinen, T. & Mustjoki, S., 29 nov 2018, I : Blood. 132, 3 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2017

Combined immunodeficiency and hypoglycemia associated with mutations in hypoxia upregulated 1

Haapaniemi, E. M., Fogarty, C., Keskitalo, S., Katayama, S., Vihinen, H., Ilander, M., Mustjoki, S., Krjutskov, K., Lehto, M., Hautala, T., Eriksson-Rosenberg, O., Jokitalo, E., Velagapudi, V., Varjosalo, M., Seppanen, M. & Kere, J., apr 2017, I : Journal of Allergy and Clinical Immunology. 139, 4, s. 1391-+ 14 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskaplig

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Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models

Hekim, C., Ilander, M., Yan, J., Michaud, E., Smykla, R., Vaha-Koskela, M., Savola, P., Tahtinen, S., Saikko, L., Hemminki, A., Kovanen, P. E., Porkka, K., Lee, F. Y. F. & Mustjoki, S., feb 2017, I : Cancer immunology research. 5, 2, s. 157-169 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Dasatinib Reversibly Disrupts Endothelial Vascular Integrity by Increasing Non-Muscle Myosin II Contractility in a ROCK-Dependent Manner

Kreutzman, A., Colom-Fernandez, B., Marcos Jimenez, A., Ilander, M., Cuesta-Mateos, C., Perez-Garcia, Y., Delgado Arevalo, C., Bruck, O., Hakanen, H., Saarela, J., Ortega-Carrion, A., de Rosendo, A., Juanes-Garcia, A., Luis Steegmann, J., Mustjoki, S., Vicente-Manzanares, M. & Munoz-Calleja, C., 1 nov 2017, I : Clinical Cancer Research. 23, 21, s. 6697-6707 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Immune control in chronic myeloid leukemia

Ilander, M. & Mustjoki, S., 3 nov 2017, I : Oncotarget. 8, 61, s. 102763-102764 2 s.

Forskningsoutput: TidskriftsbidragLedareVetenskaplig

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Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia

Ilander, M., Olsson-Stromberg, U., Schlums, H., Guilhot, J., Bruck, O., Lahteenmaki, H., Kasanen, T., Koskenvesa, P., Soderlund, S., Hoglund, M., Markevarn, B., Sjalander, A., Lotfi, K., Dreimane, A., Lubking, A., Holm, E., Bjoreman, M., Lehmann, S., Stenke, L., Ohm, L. & 11 andra, Gedde-Dahl, T., Majeed, W., Ehrencrona, H., Koskela, S., Saussele, S., Mahon, F-X., Porkka, K., Hjorth-Hansen, H., Bryceson, Y. T., Richter, J. & Mustjoki, S., maj 2017, I : Leukemia. 31, 5, s. 1108-1116 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2016

Effects of Dasatinib and Interferon-alpha Combination Treatment on the Immune System in CML

Ilander, M., Lahteenmaki, H., Olsson-Stromberg, U., Stentoft, J., Richter, J., Koskenvesa, P., Hoglund, M., Dreimane, A., Porkka, K., Gedde-Dahl, T., Gjertsen, B. T., Gruber, F. X., Stenke, L., Myhr-Eriksson, K., Markevarn, B., Lubking, A., Vestergaard, H., Udby, L., Bjerrum, O. W., Hjorth-Hansen, H. & 1 andra, Mustjoki, S., 2 dec 2016, I : Blood. 128, 22, 5 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

Intrafamily and Interfamilial Phenotype Variation and Immature Immunity in Patients With Netherton Syndrome and Finnish SPINK5 Founder Mutation

Hannula-Jouppi, K., Laasanen, S-L., Ilander, M., Furio, L., Tuomiranta, M., Marttila, R., Jeskanen, L., Häyry, V., Kanerva, M., Kivirikko, S., Tuomi, M-L., Heikkila, H., Mustjoki, S., Hovnanian, A. & Ranki, A., apr 2016, I : Jama dermatology. 152, 4, s. 435-442 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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T and NK cell mediated immunity in chronic myeloid leukaemia

Ilander, M., 2016, Helsinki : University of Helsinki. 91 s.

Forskningsoutput: AvhandlingDoktorsavhandlingSamling av artiklar

2014

Dasatinib promotes Th1-type responses in granzyme B expressing T-cells

Kreutzman, A., Ilander, M., Porkka, K., Vakkila, J. & Mustjoki, S., 1 maj 2014, I : OncoImmunology. 3, e28925.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Enlarged Memory T-Cell Pool and Enhanced Th1-Type Responses in Chronic Myeloid Leukemia Patients Who Have Successfully Discontinued IFN-alpha Monotherapy

Ilander, M., Kreutzman, A., Rohon, P., Melo, T., Faber, E., Porkka, K., Vakkila, J. & Mustjoki, S., 31 jan 2014, I : PLoS One. 9, 1, 11 s., 87794.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Immunology and Immunotherapy of Chronic Myeloid Leukemia

Ilander, M., Hekim, C. & Mustjoki, S., mar 2014, I : Current hematologic malignancy reports. 9, 1, s. 17-23 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Functional Characterization of T- and NK-Cells in Chronic Myeloid Leukemia Patients Treated with Interferon-alpha Monotherapy.

Ilander, M. M., Kreutzman, A., Rohon, P., Melo, T., Faber, E., Porkka, K., Vakkila, J. & Mustjoki, S., 16 nov 2012, I : Blood. 120, 21, 2 s.

Forskningsoutput: TidskriftsbidragMötesabstraktForskningPeer review

2011

Intracerebral Borna disease virus infection of bank voles leading to peripheral spread and reverse transcription of viral RNA

Kinnunen, P. M., Inkeroinen, H., Ilander, M., Kallio, E. R., Heikkilä, H. P., Koskela, E., Mappes, T., Palva, A., Vaheri, A., Kipar, A. & Vapalahti, O., 2011, I : PLoS One. 6, 8, s. e23622 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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