1990 …2020

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Publikationer

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2020

Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients

Dickinson, A., Saraswat, M., Syrjänen, S., Tohmola, T., Silén, R., Randén-Brady, R., Carpén, T., Hagström, J., Haglund, C., Mattila, P., Mäkitie, A., Joenväärä, S. & Silén, S., 15 jun 2020, I : PLoS One. 15, 6, 13 s., 0233974.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Elevated TLR5 expression in vivo and loss of NF-kappa B activation via TLR5 in vitro detected in HPV-negative oropharyngeal squamous cell carcinoma

Kylmä, A. K., Tolvanen, T. A., Carpén, T., Haglund, C., Mäkitie, A., Mattila, P. S., Grenman, R., Jouhi, L., Sorsa, T., Lehtonen, S. & Hagström, J., jun 2020, I : Experimental and Molecular Pathology. 114, 9 s., 104435.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Epstein-Barr virus (EBV) and polyomaviruses are detectable in oropharyngeal cancer and EBV may have prognostic impact

Carpen, T., Syrjänen, S., Jouhi, L., Randen-Brady, R., Haglund, C., Mäkitie, A., Mattila, P. S. & Hagström, J., aug 2020, I : Cancer Immunology, Immunotherapy. 69, 8, s. 1615-1626 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2019

A2ML1 and otitis media: novel variants, differential expression, and relevant pathways

Larson, E. D., Magno, J. P. M., Steritz, M. J., Llanes, E. G. D., Cardwell, J., Pedro, M., Roberts, T. B., Einarsdottir, E., Rosanes, R. A. Q., Greenlee, C., Santos, R. A. P., Yousaf, A., Streubel, S-O., Santos, A. T. R., Ruiz, A. G., Mae Lagrana-Villagracia, S., Ray, D., Yarza, T. K. L., Scholes, M. A., Anderson, C. B. & 33 andra, Acharya, A., Gubbels, S. P., Bamshad, M. J., Cass, S. P., Lee, N. R., Shaikh, R. S., Nickerson, D. A., Mohlke, K. L., Prager, J. D., Cruz, T. L. G., Yoon, P. J., Abes, G. T., Schwartz, D. A., Chan, A. L., Wine, T. M., Maria Cutiongco-de la Paz, E., Friedman, N., Kechris, K., Kere, J., Leal, S. M., Yang, I., Patel, J. A., Tantoco, M. L. C., Riazuddin, S., Chan, K. H., Mattila, P. S., Reyes-Quintos, M. R. T., Ahmed, Z. M., Jenkins, H. A., Chonmaitree, T., Hafren, L., Chiong, C. M. & Santos-Cortez, R. L. P., aug 2019, I : Human Mutation. 40, 8, s. 1156-1171 16 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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ABO Genotype and Blood Type Are Associated with Otitis Media

Wiesen, B. M., Hafren, L., Einarsdottir, E., Kere, J., Mattila, P. S. & Santos-Cortez, R. L. P., 1 nov 2019, I : Genetic Testing and Molecular Biomarkers. 23, 11, s. 823-827 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer

Carpen, T., Sorsa, T., Jouhi, L., Tervahartiala, T., Haglund, C., Syrjänen, S., Tarkkanen, J., Mohamed, H., Mäkitie, A., Hagström, J. & Mattila, P. S., aug 2019, I : Cancer Immunology, Immunotherapy. 68, 8, s. 1263-1272 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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In situ hybridization for high-risk HPV E6/E7 mRNA is a superior method for detecting transcriptionally active HPV in oropharyngeal cancer

Randen-Brady, R., Carpen, T., Jouhi, L., Syrjänen, S., Haglund, C., Tarkkanen, J., Remes, S., Mäkitie, A., Mattila, P. S., Silen, S. & Hagström, J., aug 2019, I : Human Pathology. 90, s. 97-105 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2018

FUT2 Variants Confer Susceptibility to Familial Otitis Media

UWCMG, 1 nov 2018, I : American Journal of Human Genetics. 103, 5, s. 679-690 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Long-term follow-up after ESS and balloon sinuplasty: Comparison of symptom reduction and patient satisfaction

Koskinen, A., Myller, J., Mattila, P., Penttilä, M., Silvola, J., Alastalo, I., Huhtala, H., Hytönen, M. & Toppila-Salmi, S., 2018, I : Acta Oto-Laryngologica. 138, s. 342-347 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Patients with early-stage oropharyngeal cancer can be identified with label-free serum proteomics

Tuhkuri, A., Saraswat, M., Mäkitie, A., Mattila, P., Silen, R., Dickinson, A., Carpen, T., Tohmola, T., Joenväärä, S. & Renkonen, S., 17 jul 2018, I : British Journal of Cancer. 119, 2, s. 200-212 13 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Presenting symptoms and clinical findings in HPV-positive and HPV-negative oropharyngeal cancer patients

Carpen, T., Sjöblom, A., Lundberg, M., Haglund, C., Markkola, A., Syrjänen, S., Tarkkanen, J., Mäkitie, A., Hagström, J. & Mattila, P., 2018, I : Acta Oto-Laryngologica. 138, 5, s. 513-518 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Tumor volume as a prognostic marker in p16-positive and p16-negative oropharyngeal cancer patients treated with definitive intensity-modulated radiotherapy

Carpen, T., Saarilahti, K., Haglund, C., Markkola, A., Tarkkanen, J., Hagström, J., Mattila, P. & Mäkitie, A., aug 2018, I : Strahlentherapie und Onkologie. 194, 8, s. 759-770 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2017

A mouse-to-man candidate gene study identifies association of chronic otitis media with the loci TGIF1 and FBXO11

Bhutta, M. F., Lambie, J., Hobson, L., Goel, A., Hafren, L., Einarsdottir, E., Mattila, P. S., Farrall, M., Brown, S. & Burton, M. J., 2 okt 2017, I : Scientific Reports. 7, 7 s., 12496.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Comparison of intra-operative characteristics and early post-operative outcomes between endoscopic sinus surgery and balloon sinuplasty

Koskinen, A., Mattila, P., Myller, J., Penttila, M., Silvola, J., Alastalo, I., Huhtala, H., Hytonen, M. & Toppila-Salmi, S., feb 2017, I : Acta Oto-Laryngologica. 137, 2, s. 202-206 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2016

Association of BMI-1 and p16 as prognostic factors for head and neck carcinomas

Lundberg, M., Renkonen, S., Haglund, C., Mattila, P. S., Leivo, I., Hagstrom, J. & Makitie, A. A., 3 maj 2016, I : Acta Oto-Laryngologica. 136, 5, s. 501-505 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Genome-wide association analysis reveals variants on chromosome 19 that contribute to childhood risk of chronic otitis media with effusion

Einarsdottir, E., Hafren, L., Leinonen, E., Bhutta, M. F., Kentala, E., Kere, J. & Mattila, P. S., 16 sep 2016, I : Scientific Reports. 6, 11 s., 33240.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Long-term follow-up after ESS and balloon sinuplasty: Comparison of symptom reduction and patient satisfaction

Koskinen, A., Myller, J., Mattila, P., Penttila, M., Silvola, J., Alastalo, I., Huhtala, H., Hytonen, M. & Toppila-Salmi, S., 3 maj 2016, I : Acta Oto-Laryngologica. 136, 5, s. 532-536 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2015

Predisposition to Childhood Otitis Media and Genetic Polymorphisms within the Toll-Like Receptor 4 (TLR4) Locus

Hafren, L., Einarsdottir, E., Kentala, E., Hammaren-Malmi, S., Bhutta, M. F., MacArthur, C. J., Wilmot, B., Casselbrant, M., Conley, Y. P., Weeks, D. E., Mandel, E. M., Vaarala, O., Kallio, A., Melin, M., Nieminen, J. K., Leinonen, E., Kere, J. & Mattila, P. S., 15 jul 2015, I : PLoS One. 10, 7, 14 s., 0132551.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Toll-like receptors 3, 7, and 9 in Juvenile nasopharyngeal angiofibroma

Renkonen, S., Cardell, L-O., Mattila, P., Lundberg, M., Haglund, C., Hagstrom, J. & Makitie, A. A., maj 2015, I : APMIS : Acta pathologica, microbiologica et immunologica Scandinavica. 123, 5, s. 439-444 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2014

Assessing direct and indirect airway hyperresponsiveness in children using impulse oscillometry

Kalliola, S., Malmberg, L. P., Kajosaari, M., Mattila, P. S., Pelkonen, A. S. & Makela, M. J., aug 2014, I : Annals of Allergy, Asthma, & Immunology. 113, 2, s. 166-172 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2013

Antigenic diversity and seroprevalences of Torque teno viruses in children and adults by ORF2-based immunoassays

Chen, T., Väisänen, E., Mattila, P. S., Hedman, K. & Söderlund-Venermo, M., feb 2013, I : Journal of General Virology. 94, Part 2, s. 409-417 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Extraintestinal Clostridium difficile Infections

Mattila, E., Arkkila, P., Mattila, P. S., Tarkka, E., Tissari, P. & Anttila, V-J., 15 sep 2013, I : Clinical Infectious Diseases. 57, 6, s. E148-E153 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Rifaksimiini uusiutuvan Clostridium difficile -infektion hoidossa

Mattila, E., Arkkila, P., Mattila, P., Tarkka, E., Tissari, P. & Anttila, V-J. A., 2013, I : Duodecim. 129, 1, s. 91 1 s.

Forskningsoutput: TidskriftsbidragArtikelProfessionell

Rifaximin in the treatment of recurrent Clostridium difficile infection

Mattila, E., Arkkila, P., Mattila, P. S., Tarkka, E., Tissari, P. & Anttila, V. -J., jan 2013, I : Alimentary Pharmacology & Therapeutics. 37, 1, s. 122-128 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2012

Adenoidectomy in young children and serum IgG antibodies to pneumococcal surface protein A and choline binding protein A

Mattila, P. S., Hammaren-Malmi, S., Saxen, H., Kaijalainen, T., Kayhty, H. & Tarkkanen, J., nov 2012, I : International Journal of Pediatric Otorhinolaryngology. 76, 11, s. 1569-1574 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Biotin IgM Antibodies in Human Blood: A Previously Unknown Factor Eliciting False Results in Biotinylation-Based Immunoassays

Chen, T., Hedman, L., Mattila, P. S., Jartti, L., Jartti, T., Ruuskanen, O., Söderlund-Venermo, M. & Hedman, K., 2012, I : PLoS One. 7, 8, s. Article Number: e42376 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Fecal Transplantation, Through Colonoscopy, Is Effective Therapy for Recurrent Clostridium difficile Infection

Mattila, E., Uusitalo-Seppala, R., Wuorela, M., Lehtola, L., Nurmi, H., Ristikankare, M., Moilanen, V., Salminen, K., Seppala, M., Mattila, P. S., Anttila, V-J. & Arkkila, P., 2012, I : Gastroenterology. 142, 3, s. 490-496 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Genetic background and the risk of otitis media

Hafrén, L., Kentala, E., Järvinen, T. M., Leinonen, E., Onkamo, P., Kere, J. & Mattila, P., 2012, I : International Journal of Pediatric Otorhinolaryngology. 76, 1, s. 41-44 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Transforming growth factor beta 1 genotype and p16 as prognostic factors in head and neck squamous cell carcinoma

Lundberg, M., Leivo, I., Saarilahti, K., Makitie, A. A. & Mattila, P. S., 2012, I : Acta Oto-Laryngologica. 132, 9, s. 1006-1012 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Treatment of Chronic Rhinosinusitis With Antibiotics

Mattila, P. S., 2012, I : Clinical Infectious Diseases. 54, 1, s. 69-70 2 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskaplig

Type I and III collagen degradation products in serum predict patient survival in head and neck squamous cell carcinoma

Nurmenniemi, S., Koivula, M-K., Nyberg, P., Tervahartiala, T., Sorsa, T., Mattila, P. S., Salo, T. & Risteli, J., 2012, I : Oral Oncology. 48, 2, s. 136-140 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2011

Antibody responses to tetanus and diphtheria vaccine in chronic and recurrent rhinosinusitis

Tahkokallio, O., Koskinen, A., Kentala, E., Olander, R-M. & Mattila, P. S., 2011, I : Rhinology : official organ of the International rhinologic society. 49, 1, s. 90-94 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Clinical spectrum of bacteraemic Fusobacterium infections: From septic shock to nosocomial bacteraemia

Nohrstrom, E., Mattila, T., Pettilä, V., Kuusela, P. I., Carlson, P., Kentala, E. & Mattila, P. S., 2011, I : Scandinavian Journal of Infectious Diseases. 43, 6-7, s. 463-470 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Increased incidence of oropharyngeal cancer and p16 expression

Lundberg, M., Leivo, I., Saarilahti, K., Mäkitie, A. A. & Mattila, P. S., 2011, I : Acta Oto-Laryngologica. 131, 9, s. 1008-1011 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Seroepidemiology of the Newly Found Trichodysplasia Spinulosa-Associated Polyomavirus

Chen, T., Mattila, P. S., Jartti, T., Ruuskanen, O., Soderlund-Venermo, M. & Hedman, K., 2011, I : Journal of Infectious Diseases. 204, 10, s. 1523-1526 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Serological evidence of Merkel cell polyomavirus primary infections in childhood

Chen, T., Hedman, L., Mattila, P., Jartti, T., Ruuskanen, O., Söderlund-Venermo, M. & Hedman, K., 2011, I : Journal of Clinical Virology. 50, 2, s. 125-129 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2010

Adenoidectomy and nasopharyngeal carriage of Streptococcus pneumoniae in young children

Mattila, P. S., Hammaren-Malmi, S., Saxen, H., Kaijalainen, T., Käyhty, H. & Tarkkanen, J., 2010, I : Archives of Disease in Childhood. 95, s. 696-702 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Amoxicillin treatment increases rate of late recurrence of acute otitis media in young children

Mattila, P. S., 2010, I : The Journal of Pediatrics. 156, 1, s. 163 1 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Plasma level of tissue inhibitor of matrix metalloproteinase-1 but not that of matrix metalloproteinase-8 predicts survival in head and neck squamous cell cancer

Pradhan-Palikhe, P., Vesterinen, T., Tarkkanen, J., Leivo, I., Sorsa, T., Salo, T. & Mattila, P. S., 2010, I : Oral Oncology. 46, 7, s. 514-518 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

TGF beta 1 genetic polymorphism is associated with survival in head and neck squamous cell carcinoma independent of the severity of chemoradiotherapy induced mucositis

Lundberg, M., Saarilahti, K., Mäkitie, A. A. & Mattila, P. S., 2010, I : Oral Oncology. 46, 5, s. 369-372 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2009

ASSOCIATION BETWEEN TRANSFORMING GROWTH FACTOR beta 1 GENETIC POLYMORPHISM AND RESPONSE TO CHEMORADIOTHERAPY IN HEAD AND NECK SQUAMOUS CELL CANCER

Lundberg, M., Pajusto, M., Koskinen, W. J., Makitie, A. A., Aaltonen, L-M. & Mattila, P. S., 2009, I : Head & Neck. 31, 5, s. 664-672 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Effect of adenoidectomy on respiratory function: a randomised prospective study

Mattila, P. S., Hammaren-Malmi, S., Pelkonen, A., Malmberg, L. P., Mäkelä, M., Saxen, H., Tarkkanen, J. & Malmberg, P., 2009, I : Archives of Disease in Childhood. 94, 5, s. 366-370 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2008

Exercise-induced changes in respiratory impedance in young wheezy children and nonatopic controls

Malmberg, P., Mäkelä, M., Mattila, P., Hammaren-Malmi, S. & Pelkonen, A., 2008, I : Pediatric Pulmonology. 43, 6, s. 538-544 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Factor H binding as a complement evasion mechanism for an anaerobic pathogen, Fusobacterium necrophorum

Friberg, N., Carlson, P., Kentala, E., Mattila, P. S., Kuusela, P., Meri, S. & Jarva, H., 2008, I : Journal of Immunology. 181, 12, s. 8624-8632 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Hereditary hemorrhagic telangiectasia type 1 and 2 mutations in Finland

Sankelo, M., Halme, M., Laitinen, T. & Mattila, P. S., 2008, I : Acta Oto-Laryngologica. 128, s. 1238-1241 4 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review