• PL 63 (Haartmaninkatu 8)

    00014

    Finland

20072019

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2019

Activation of the TRKB receptor mediates the panicolytic-like effect of the NOS inhibitor aminoguanidine

Ribeiro, D. E., Casarotto, P. C., Júnior, A. S., Fernandes, G. G., Pinheiro, L. C., Tanus- Santos, J. E., Zangrossi Jr, H., Silveira Guimarães, F., Lourenço Joca, S. R. & Biojone, C., 13 jul 2019, I : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 93, s. 232-239 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Dual mechanism of TRKB activation by anandamide through CB1 and TRPV1 receptors

Diniz, C. R. A. F., Biojone, C., Joca, S. R. L., Rantamäki, T., Castren, E., Guimaraes, F. S. & Casarotto, P. C., 21 feb 2019, I : PeerJ. 7, 21 s., 6493.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2

Fred, S. M., Laukkanen, L., Brunello, C. A., Vesa, L., Göös, H., Cardon, I., Moliner, R., Maritzen, T., Varjosalo, M., Casarotto, P. C. & Castren, E., 29 nov 2019, I : Journal of Biological Chemistry. 294, 48, s. 18150-18161 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Reduced P2X receptor levels are associated with antidepressant effect in the learned helplessness model

Ribeiro, D. E., Casarotto, P. C., Staquini, L., Pinto e Silva, M. A., Biojone, C., Wegener, G. & Joca, S., 21 okt 2019, I : PeerJ. 7, 17 s., 7834.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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TrkB-ICD Fragment, Originating From BDNF Receptor Cleavage, Is Translocated to Cell Nucleus and Phosphorylates Nuclear and Axonal Proteins

Fonseca-Gomes, J., Jerónimo-Santos, A., Lesnikova, A., Casarotto, P., Castrén, E., Sebastião, A. M. & Diógenes, M. J., 1 feb 2019, I : Frontiers in Molecular Neuroscience. 12, 8 s., 4.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2018

Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN

Diniz, C. R. A. F., Casarotto, P. C., Fred, S. M., Biojone, C., Castrén, E. & Joca, S. R. L., jun 2018, I : Neuropharmacology. 135, s. 163-171 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Elastase-2 Knockout Mice Display Anxiogenic- and Antidepressant-Like Phenotype: Putative Role for BDNF Metabolism in Prefrontal Cortex

Diniz, C. R. A. F., Becari, C., Lesnikova, A., Biojone, C., Salgado, M. C. O., Salgado, H. C., Resstel, L. B. M., Guimaraes, F. S., Castren, E., Casarotto, P. C. & Joca, S. R. L., aug 2018, I : Molecular Neurobiology. 55, 8, s. 7062-7071 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Inducible nitric oxide synthase (NOS2) knockout mice as a model of trichotillomania

Casarotto, P. C., Biojone, C., Montezuma, K., Cunha, F. Q., Joca, S. R. L., Castren, E. & Guimaraes, F. S., 17 apr 2018, I : PeerJ. 6, s. e4635 13 s., 4635.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine

Pryazhnikov, E., Mugantseva, E., Casarotto, P., Kolikova, J., Fred, S. M., Toptunov, D., Afzalov, R., Hotulainen, P., Voikar, V., Terry-Lorenzo, R., Engel, S., Kirov, S., Castren, E. & Khiroug, L., 24 apr 2018, I : Scientific Reports. 8, 12 s., 6464.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2017

Isoflurane produces antidepressant effects and induces TrkB signaling in rodents

Antila, H., Ryazantseva, M., Popova, D., Sipilä, P., Guirado, R., Kohtala, S., Yalcin, I., Lindholm, J., Vesa, L., Sato, V., Cordeira, J., Autio, H., Kislin, M., Rios, M., Joca, S., Casarotto, P., Khiroug, L., Lauri, S., Taira, T., Castren, E. & 1 andra, Rantamäki, T., 10 aug 2017, I : Scientific Reports. 7, 12 s., 7811.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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Monoamine involvement in the antidepressant-like effect induced by P2 blockade

Diniz, C. R. A. F., Rodrigues, M., Casarotto, P. C., Pereira, V. S., Crestani, C. C. & Joca, S. R. L., 2017, I : Brain Research . 1676, s. 19-27 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

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2016

NMDA-NO signaling in the dorsal and ventral hippocampus time-dependently modulates the behavioral responses to forced swimming stress

Diniz, C. R. A. F., Casarotto, P. & Joca, S. R. L., 1 jul 2016, I : Behavioural Brain Research. 307, s. 126-136 11 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2015

BDNF-TRKB signaling system of the dorsal periaqueductal gray matter is implicated in the panicolytic-like effect of antidepressant drugs

Casarotto, P. C., dos Santos, P. C., Lucas, G. A., Biojone, C., Pobbe, R. L. H., Vilela-Costa, H. H., Joca, S. R. L., Guimaraes, F. S. & Zangrossi, H., jun 2015, I : European Neuropsychopharmacology. 25, 6, s. 913-922 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Interplay Between Nitric Oxide and Brain-Derived Neurotrophic Factor in Neuronal Plasticity

Biojone, C., Casarotto, P. C., Joca, S. R. & Castren, E., 2015, I : C N S & Neurological Disorders. 14, 8, s. 979-987 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2014

Cannabidiol reverses the mCPP-induced increase in marble-burying behavior

Nardo, M., Casarotto, P. C., Gomes, F. V. & Guimaraes, F. S., okt 2014, I : Fundamental & Clinical Pharmacology. 28, 5, s. 544-550 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2013

Antidepressant- and anticompulsive-like effects of purinergic receptor blockade: Involvement of nitric oxide

Pereira, V. S., Casarotto, P. C., Hiroaki-Sato, V. A., Sartim, A. G., Guimaraes, F. S. & Joca, S. R. L., dec 2013, I : European Neuropsychopharmacology. 23, 12, s. 1769-1778 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

The antimanic-like effect of phenytoin and carbamazepine on methylphenidate-induced hyperlocomotion: role of voltage-gated sodium channels

Tonelli, D. A. G., Pereira, M., Siba, I. P., Martynhak, B. J., Correia, D., Casarotto, P. C., Biojone, C., Guimaraes, F. S., Joca, S. L. R. & Andreatini, R., 2013, I : Fundamental & Clinical Pharmacology. 27, 6, s. 650-655 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2012

Fine-tuning of defensive behaviors in the dorsal periaqueductal gray by atypical neurotransmitters

Fogaca, M. V., Lisboa, S. F., Aguiar, D. C., Moreira, F. A., Gomes, F. V., Casarotto, P. C. & Guimaraes, F. S., apr 2012, I : Brazilian Journal of Medical and Biological Research. 45, 4, s. 357-365 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Intrahippocampal injection of brain-derived neurotrophic factor increases anxiety-related, but not panic-related defensive responses: involvement of serotonin

Casarotto, P. C., de Bortoli, V. C. & Zangrossi, H., feb 2012, I : Behavioural Pharmacology. 23, 1, s. 80-88 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Opposing Roles for Cannabinoid Receptor Type-1 (CB1) and Transient Receptor Potential Vanilloid Type-1 Channel (TRPV1) on the Modulation of Panic-Like Responses in Rats

Casarotto, P. C., Terzian, A. L. B., Aguiar, D. C., Zangrossi, H., Guimaraes, F. S., Wotjak, C. T. & Moreira, F. A., jan 2012, I : Neuropsychopharmacology. 37, 2, s. 478-486 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2011

Anti-aversive effects of the atypical antipsychotic, aripiprazole, in animal models of anxiety

Biojone, C., Casarotto, P. C., Resstel, L. B., Zangrossi, H., Guimaraes, F. S. & Moreira, F. A., jun 2011, I : Journal of Psychopharmacology. 25, 6, s. 801-807 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Facilitation of CB1 receptor-mediated neurotransmission decreases marble burying behavior in mice

Gomes, F. V., Casarotto, P. C., Resstel, L. B. M. & Guimaraes, F. S., 30 mar 2011, I : Progress in Neuro-Psychopharmacology & Biological Psychiatry. 35, 2, s. 434-438 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2010

Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors

Casarotto, P. C., Gomes, F. V., Resstel, L. B. M. & Guimaraes, F. S., jul 2010, I : Behavioural Pharmacology. 21, 4, s. 353-358 6 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Panicolytic-like effect of BDNF in the rat dorsal periaqueductal grey matter: the role of 5-HT and GABA

Casarotto, P. C., de Bortoli, V. C., de Aguiar Correa, F. M., Moraes Resstel, L. B. & Zangrossi, H., jun 2010, I : International Journal of Neuropsychopharmacology. 13, 5, s. 573-582 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2007

Dexamethasone-induced anhedonia: antidepressant reversion, hippocampal BDNF level, and role of glucocorticoids receptors

Andreatini, R., Casarotto, P. C. & Zanata, S. M., okt 2007, I : European Neuropsychopharmacology. 17, s. S362-S362 1 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Repeated paroxetine treatment reverses anhedonia induced in rats by chronic mild stress or dexamethasone

Casarotto, P. C. & Andreatini, R., nov 2007, I : European Neuropsychopharmacology. 17, 11, s. 735-742 8 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review