Tiina Paunio

  • PL 22 (Välskärinkatu 12)

    00014

    Finland

  • PL 22 (Välskärinkatu 12)

    HELSINGIN YLIOPISTO

    Finland

  • Viikinkaari 5, Biocenter 2

    00790 Helsinki

    Finland

1992 …2025

Research output per year

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Personlig profil

Meritförteckning

Meritförteckning

I performed my PhD work at the laboratory of Professor Leena Peltonen-Palotie  during 1990-1995. This work led to DNA diagnostics of gelsolin-related amyloidosis and revelation of pathogenic processing of mutant gelsolin in neuronal cells. During a 2-year post doc period (1996-1998) at LGN-CNRS, Paris, I developed novel recombinant adenoviral vectors for gene therapy on an experimental model of Parkinson’s disease. Then, my focus shifted towards research on psychiatric traits and I started working as a project leader for large international collaboration on schizophrenia. This work led to understanding the truly heterogeneous background of psychosis as well as connections between genes, cognitive disturbances, and schizophrenia.

From year 2003, my main research focus has been on understanding the molecular mechanisms for disturbed mood and sleep and their relationship. We have revealed association of two genes, DISC1 and DAOA, to intermediate traits for BPD and we were able to replicate some of the findings from earlier genome-wide association studies. We found in a large nation-wide cohort of twins that poor sleep predicted depressed mood in a consistent pattern, while depressed mood did not predict poor sleep, evidencing for the central role of disturbed sleep in mood disorders. We have also found inter-individual variability in sleep quality-related responses to stressful life events and relation of childhood traumatic events to insomnia in adulthood. We found in a systematic association study in a population-based sample that some susceptibility genes associate to depression only in the presence of disturbed sleep. We also found a link between a bipolar susceptibility gene and visual performance, evidencing further for the direct neurobiological link between visual perception, circadian rhythm, and regulation of mood.

Vetenskapsgrenar

  • 3112 Neurovetenskaper

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer

Maternal and paternal depressive symptoms and children's emotional problems at the age of 2 and 5 years: a longitudinal study

Pietikäinen, J. T., Kiviruusu, O., Kylliäinen, A., Pölkki, P., Saarenpää-Heikkilä, O., Paunio, T. & Paavonen, E. J., feb 2020, I : Journal of Child Psychology & Psychiatry. 61, 2, s. 195-204 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Normal sleep development in infants: findings from two large birth cohorts

Paavonen, E. J., Saarenpaa-Heikkila, O., Morales-Munoz, I., Virta, M., Häkälä, N., Polkki, P., Kylliainen, A., Karlsson, H., Paunio, T. & Karlsson, L., 20 jan 2020, I : Sleep Medicine.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Parent-reported early sleep problems and internalising, externalising and dysregulation symptoms in toddlers

Morales-Munoz, I., Lemola, S., Saarenpää-Heikkilä, O., Kylliainen, A., Paunio, T., Polkki, P., Broome, M. R. & Paavonen, E. J., 2020, I : BMJ Paediatrics Open. 4, s. 1-9 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

Psychosocial treatments for employees with non-specific and persistent physical symptoms associated with indoor air: A randomised controlled trial with a one-year follow-up

Selinheimo, S., Vuokko, A., Hublin, C., Järnefelt, H., Karvala, K., Sainio, M., Suojalehto, H. & Paunio, T., apr 2020, I : Journal of Psychosomatic Research. 131, 9 s., 109962.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Tietoisuustaidot auttavat stressinhallinnassa

Repo, S., Renkonen, R. & Paunio, T., 1 apr 2020, I : Duodecim. 136, 7, s. 725-726 2 s.

Forskningsoutput: TidskriftsbidragLedareVetenskapligPeer review

Projekter

Tietoisuustaitoja opiskelijoille

Repo, S., Paunio, T., Elovainio, M., Pyörälä, E., Saarinen, J., Peltola, K., Härkönen, T. & Holopainen, M.

01/01/201831/12/2025

Projekt: Forskningsprojekt

Studies and wellbeing - Opiskelu ja hyvinvointi -tutkimus

Paunio, T., Pyörälä, E., Saarinen, J., Peltola, K., Härkönen, T., Vartia, J. & Elovainio, M.

09/12/2016 → …

Projekt: Forskningsprojekt

Lapsen uni ja terveys

Paavonen, J., Paunio, T., Saarenpää-Heikkilä, O., Pölkki, P., Kylliainen, A., Rusanen, E. & Pietiläinen, K.

01/01/2010 → …

Projekt: Forskningsprojekt

Priser

Vuoden artikkeli Lääkärilehdessä

Juulia Paavonen (!!Recipient), Tiina Maria Paunio (!!Recipient) & Tytti Solantaus (!!Recipient), 2009

Pris: Pris och hedersbetygelser

Aktiviteter

AMEE 2019

Saara Repo (Talare: Presentation), Tiina Paunio (Närvarande), Eeva Pyörälä (Närvarande), Marianne Holopainen (Närvarande), panajiota Räsänen (Närvarande), Marko Elovainio (Närvarande)
24 aug 201928 aug 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

AMEE 2019

Taina Hintsa (Talare: Presentation), Anne Helena Monni (Närvarande), Eeva Pyörälä (Närvarande), Marko Elovainio (Närvarande), Saara Repo (Närvarande), Tiina Paunio (Närvarande)
24 aug 201928 aug 2019

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

AMEE 2017

Tiina Maria Paunio (Poster presentation), Eeva Pyörälä (Poster presentation), Jussi Jukka Saarinen (Poster presentation), Kari Risto Johannes Peltola (Närvarande), Jonne Juntura (Poster presentation), Marko Juhani Elovainio (Poster presentation)
26 aug 201730 aug 2017

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Hosting a Seminar at Evidence-Based Psychotherapy

Tiina Paunio (Ordförande)
11 jan 2016

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

The 2nd Finnish Symposium of Biological Psychiatry, Finland

Zuzanna Misiewicz (Medlem i organisationskommitté), Iiris Maaria Hovatta (Medlem i organisationskommitté), Tiina Maria Paunio (Medlem i organisationskommitté)
19 dec 2016

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

Tidningsurklipp

Interview for Anna: Is it something serious?

Tiina Paunio & Kari Tikkinen

24/11/2018

1 objekt av Mediabevakning

Press/media: !!Press / Media

Interview on Iltalehti

Tiina Paunio

02/01/2017

1 Mediabidrag

Press/media: !!Press / Media

Interview on Reuters

Tiina Paunio

10/11/2016

1 Mediabidrag

Press/media: !!Press / Media

Interview on Helsingin Sanomat

Tiina Paunio

28/10/2016

1 Mediabidrag

Press/media: !!Press / Media

Interview on Yleisradio

Tiina Paunio

27/10/2016

1 Mediabidrag

Press/media: !!Press / Media