Tobias Freitag

Personlig profil

Meritförteckning

Tobias Freitag, MD, is a medical researcher and experimental immunologist, trained in gastroenterology and rheumatology. His scientific research is focused on (mucosal) immunology and translational medicine, autoimmune diseases, particularly celiac disease, mechanisms of tolerance to intestinal antigens (food, microbial and self-proteins), regulatory T cell function and rodent disease models. He has been a principal investigator of the Finnish-Swedish NARPANord consortium, investigating pathogenesis of type 1 narcolepsy, and is currently a member of the Academy of Finland Personalized Health-DIGIN Health research consortium, searching for microbial triggers of celiac disease. Starting from 2019, he will contribute as Junior Researcher to the Translational Immunology Research Program at the University of Helsinki, studying therapeutic immune tolerance induction.

Vetenskapsgrenar

311 Basmedicin
312 Klinisk medicin

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer 2001 2017

8 Artikel
4 Konferensartikel
3 Översiktsartikel
2 Kapitel
1 Mer
- 1 Doktorsavhandling

Deep sequencing of blood and gut T-cell receptor beta-chains reveals gluten-induced immune signatures in celiac disease

Yohannes, D. A., Freitag, T. L., de Kauwe, A., Kaukinen, K., Kurppa, K., Wacklin, P., Mäki, M., Arstila, T. P., Anderson, R. P., Greco, D. & Saavalainen, P., 21 dec 2017, I : Scientific Reports. 7, 12 s., 17977.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Öppen tillgång

Fil

Antigenic Differences between AS03 Adjuvanted Influenza A (H1N1) Pandemic Vaccines: Implications for Pandemrix-Associated Narcolepsy Risk

Vaarala, O., Vuorela, A., Partinen, M., Baumann, M., Freitag, T. L., Meri, S., Saavalainen, P., Jauhiainen, M., Soliymani, R., Kirjavainen, T., Olsen, P., Saarenpaa-Heikkila, O., Rouvinen, J., Roivainen, M., Nohynek, H., Jokinen, J., Julkunen, I. & Kilpi, T., 15 dec 2014, I : PLoS One. 9, 12, 23 s., 114361.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Öppen tillgång

Fil

Wheat amylase trypsin inhibitors drive intestinal inflammation via activation of toll-like receptor 4

Junker, Y., Zeissig, S., Kim, S-J., Barisani, D., Wieser, H., Leffler, D. A., Zevallos, V., Libermann, T. A., Dillon, S., Freitag, T. L., Kelly, C. P. & Schuppan, D., 17 dec 2012, I : Journal of Experimental Medicine. 209, 13, s. 2395-2408 14 s.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review

Human Risk Allele HLA-DRB1*0405 Predisposes Class II Transgenic Ab0 NOD Mice to Autoimmune Pancreatitis

Freitag, T. L., Cham, C., Sung, H-H., Beilhack, G. F., Durinovic-Bello, I., Patel, S. D., Bronson, R. T., Schuppan, D. & Sonderstrup, G., 2010, I : Gastroenterology. 139, 1, s. 281-291 11 s.

Forskningsoutput: Tidskriftsbidrag › Artikel › Vetenskaplig › Peer review