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Personlig profil

Meritförteckning

 

ORCID: 0000-0001-6169-5035

 

CURRENT POSITIONS

** University Lecturer

Chancellor's Research Fellow in Medicinal Chemistry

Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, United Kingdom

 

**Adjunct Professor & Principal Investigator

Drug Discovery Programme, Faculty of Pharmacy, University of Helsinki, Finland

 

EDUCATION AND DEGREES AWARDED

**Fellow of the Higher Education Academy, UK (FHEA), 2017

**Title of “Docent” (Adjunct Professor) in Pharmaceutical Chemistry, University of Helsinki, Finland, 2015

**Ph.D. in Pharmaceutical Organic Chemistry, University of Coimbra, Portugal & University of Maryland, USA, (highest-scoring grade, “Passed with Distinction and Honours”), 2008

**Degree in Pharmaceutical Sciences (Pharm.D.), University of Coimbra, Portugal, Grade 17 out of 20 (First-class honours), awarded with the “ Sociedade Farmacêutica Lusitana Award” (best student of Pharmaceutical Sciences of the year in Portugal), 2003

 

RESEARCH AREAS

Drug Discovery, Medicinal Chemistry, Natural Products, Antimicrobial and anti-biofilm agents & materials, Neglected diseases, Cancer, (Neuro)inflammation

 

MAJOR FUNDING SOURCES

The Finnish Funding Agency for Innovation (TEKES); Huonekalusäätio; University of Helsinki Research Funds; Magnus Ehrnrooth Foundation; Portuguese Science and Technology Foundation (FCT); FP7-HEALTH-2013-INNOVATION-1 (European Funding); Academy of Finland; Tenovus Sctoland

 

CURRENT COMPOSITION OF RESEARCH GROUP

Doctoral students

Declan Mullen (Oct 2018 - ); Next generation bio-based antimicrobial agents

Ghada Hassan (Sep 2016-); Sustainable antimicrobial coatings

Tiina Ahonen (Sep 2014-); New drugs for chronic pain

Nina Forsman (co-supervisor; Sep 2016-); Sustainable multifunctional coatings for textiles and other cellulosic materials

 

FORMER RESEARCH GROUP MEMBERS

Post-doctoral researchers

Dr. Xing Wan (May 2017- Jan 2018); Sustainable antimicrobial coatings

Dr. Leena Keurulainen (Sep 2016 - Apr 2017); Sustainable antimicrobial coatings

 

Doctoral students

Dr. Laura Kolsi (main supervisor, graduated 2019); Synthesis of Abietane-Type Diterpenoids with Anticancer Activity

Dr. Raisa Haavikko (co-supervisor; graduated 2015); Synthesis of betulins with new bioactivities

Dr. Nehad El-Salamouni (visiting doctoral student; graduated 2013); Design and synthesis of some novel phenolic compounds and their quinone oxidation products of potential biological activities

 

M.Sc. students

M.Sc. Ruaraidh MacGregor (main supervisor, graduated 2018), Cellulose antimicrobial solutions

M.Sc. Graeme Lester (main supervisor, graduated 2018), The anticancer activity of picealactones

M.Sc. Declan Mullen (main supervisor, graduated 2018); Targeting metabolic serine hydrolases for the development of new anti-inflammatory drug leads

M.Sc. Henni-Karoliina Ropponen (main supervisor, graduated 2018); Exploiting the Potential of Abietane-type Diterpenoids for the Design and Synthesis of Antimicrobial and Anti-biofilm Agents

M.Sc. Peter Grutschreiber (co-supervisor, graduated 2017); Synthesis and characterisation of morphine derivatives as intermediates in development of new compounds for treatment of chronic pain

M.Sc. Tiina Mäenpää (co-supervisor, graduated 2017); Derivatives of abietic acid and their bioactivity

M.Sc. Eunice Cavalheiro (co-supervisor, graduated 2017); Synthesis of 5-methylene(thio)ureas (thio)barbiturates as potential xanthine oxidase inhibitors

M.Sc. Sara Krogerus (co-supervisor, graduated 2016); Benzylic oxidations of dehydroabietic acid derivatives at positions 7 and 15

M.Sc. Ghada Hassan (main supervisor, graduated 2016); Synthesis of abietic and dehydroabietic acid derivatives to target bacterial biofilms

M.Sc. Augustin Long (co-supervisor, graduated 2014); Modification of resin acids for the production of biologically active molecules

M.Sc. Anna-Kaarina Palomäki (co-supervisor; graduated 2013); Lääkeaineisiin ja rohdoksiin liittyvien tutkimuksellisten kokeellisten töiden kehittäminen lukion kemianopetukseen

 

Vetenskapsgrenar

  • 317 Farmaci
  • 116 Kemi

Internationellt och inhemskt samarbete Publikationer och projekt inom de senaste fem åren.

Publikationer 2005 2019

Regioselective Benzylic Oxidation of Aromatic Abietanes: Application to the Semisynthesis of the Naturally Occurring Picealactones A, B and C

Kolsi, L. E., Krogerus, S., Brito, V., Rüffer, T., Lang, H., Yli-Kauhaluoma, J. T., Silvestre, S. & Moreira, V. M., 22 aug 2017, I : ChemistrySelect. 2, 24, s. 7008-7012 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

What is medicinal chemistry? – Demystifying a rapidly evolving discipline!

Moreira, V. M., 2017, (Insänt) I : MedChemComm. 9

Forskningsoutput: TidskriftsbidragArtikelProfessionell

Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi - SPECIAL ISSUE "NEW TALENT: EUROPE"

Vahermo, M., Krogerus, S., Nasereddin, A., Kaiser, M., Brun, R., Jaffe, C. L., Yli-Kauhaluoma, J. & Moreira, V. M., 2016, I : MedChemComm. 7, 3, s. 457-463 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Öppen tillgång
Fil

New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity

Manner, S., Vahermo, M., Skogman, M., Krogerus, S., Vuorela, P. M., Yli-Kauhaluoma, J., Fallarero, A. & Moreira, V. M., 21 jul 2015, I : European Journal of Medicinal Chemistry. 102, s. 68-79 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Drug repositioning: a machine-learning approach through data integration

Napolitano, F., Zhao, Y., Moreira, V. M., Tagliaferri, R., Kere, J., D'Amato, M. & Greco, D., 22 jun 2013, I : Journal of Cheminformatics. 5, Article Number: 30 , 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Projekter 2011 2018

Priser

Chancellor's Research Fellowship

Vânia M. Moreira (!!Recipient), sep 2017

Pris: Pris och hedersbetygelser

Doctoral Scholarship (SFRH/BD/12508/2003)

Vânia M. Moreira (!!Recipient), 2003

Pris: Pris och hedersbetygelser

Post-doctoral Fellowship (SFRH/BPD/45037/2008)

Vânia M. Moreira (!!Recipient), 2009

Pris: Pris och hedersbetygelser

Semi-finalist team in OneStart Competition: GFL mimetics, Helsinki

Vânia M. Moreira (!!Recipient), 5 mar 2013

Pris: Pris och hedersbetygelser

Aktiviteter 2003 2017

COST Action CM1307, “Targeted chemotherapy towards diseases caused by endoparasites“ (Extern organisation)

Vânia M. Moreira (Medlem)
jan 2016

Aktivitet: MedlemskapstyperMedlemskap eller annan role i inhemsk/internationell kommitté, råd, styrelse

Member of the International Scientific Advisory Committee of the XXIV EFMC International Symposium on Medicinal Chemistry (EFMC-ISMC)

Vânia M. Moreira (Medlem av vetenskaplig kommitté)
aug 2016sep 2016

Aktivitet: Typer för deltagande i eller organisering av evenemangArrangemang av och deltagande i konferens/workshop/kurs/seminarium

University of Strathclyde

Vânia M. Moreira (Besökande forskare)
maj 2017aug 2017

Aktivitet: Typer för besök till extern institutionAkademisk besök på annan institution

Invited talk, International Caparica Christmas Congress on Translational Chemistry

Vânia M. Moreira (!!Speaker)
dec 2017

Aktivitet: Typer för tal eller presentation!!Invited talk

Design of new antibacterial coating materials

Vânia M. Moreira (Handledare)
sep 2016

Aktivitet: ExaminationstyperHandledare eller bihandledare av doktorsavhandling

Press / media

HY news: Tutkijat kaivautuvat kivun juurille

Vânia M. Moreira

10/12/2013

1 mediabidrag

Press/media: !!Press / Media

Curing prostate cancer without side effects

Vânia M. Moreira

01/01/2012

1 mediabidrag

Press/media: !!Press / Media