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Publikationer 2005 2019

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2019

Dehydroabietylamine-Based Cellulose Nanofibril Films: A New Class of Sustainable Biomaterials for Highly Efficient, Broad-Spectrum Antimicrobial Effects

Hassan, G. A. M. S., Forsman, N., Wan, X., Keurulainen, L., Bimbo, L. M., Johansson, L-S., Sipari, N., Yli-Kauhaluoma, J. T., Zimmermann, R., Stehl, S., Werner, C., Saris, P. E. J., Österberg, M. & Moreira, V. M., 4 mar 2019, I : ACS Sustainable Chemistry & Engineering. 7, 5, s. 5002-5009 8 s.

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Pyrazine-Fused Triterpenoids Block the TRPA1 Ion Channel in Vitro and Inhibit TRPA1-Mediated Acute Inflammation in Vivo

Mäki-Opas, I., Hämäläinen, M., Moilanen, L., Haavikko, R. H., Ahonen, T. J., Alakurtti, S., Moreira, V. M., Muraki, K., Yli-Kauhaluoma, J. T. & Moilanen, E., 19 jun 2019, I : ACS chemical neuroscience. 10, 6, s. 2848-2857 10 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2018

Catalytic, Tunable, One-Step Bismuth(III) Triflate Reaction with Alcohols: Dehydration Versus Dimerization

Kolsi, L. E., Yli-Kauhaluoma, J. & Moreira, V. M., 9 aug 2018, I : ACS Omega. 3, 8, s. 8836–8842 7 s.

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Dehydroabietic oximes halt pancreatic cancer cell growth in the G1 phase through induction of p27 and downregulation of cyclin D1

Kolsi, L. E., Leal, A. S., Yli-Kauhaluoma, J., Liby, K. T. & Moreira, V. M., 29 okt 2018, I : Scientific Reports. 8, s. 1-13 13 s., 15923.

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Discovery of 12-thiazole abietanes as selective inhibitors of the human metabolic serine hydrolase hABHD16A

Ahonen, T. J., Savinainen, J. R., Yli-Kauhaluoma, J. T., Kalso, E. A., Laitinen, J. T. & Moreira, V. M., 13 dec 2018, I : ACS Medicinal Chemistry Letters. 9, 12, s. 1269-1273 9 s.

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Synthesis of 7β-hydroxy-8-ketone opioid derivatives with antagonist activity at mu- and delta-opioid receptors

Ahonen, T. J., Rinne, M., Grutschreiber, P., Mätlik, K., Airavaara, M., Schaarschmidt, D., Lang, H., Reiss, D., Xhaard, H., Gaveriaux-Ruff, C., Yli-Kauhaluoma, J. & Moreira, V. M., 10 maj 2018, I : European Journal of Medicinal Chemistry. 151, s. 495-507 13 s.

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Trisubstituted barbiturates and thiobarbiturates: Synthesis and biological evaluation as xanthine oxidase inhibitors, antioxidants, antibacterial and anti-proliferative agents

Figueiredo, J., Serrano, J. L., Cavalheiro, E., Keurulainen, L., Yli-Kauhaluoma, J. T., Moreira, V. M., Ferreira, S., Domingues, F. C., Silvestre, S. & Almeida, P., 1 jan 2018, I : European Journal of Medicinal Chemistry. 143, s. 829-842 14 s.

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2017

Antibacterial profiling of abietane-type diterpenoids

Helfenstein, A., Vahermo, M. M. A., Nawrot, D. A., Demirci, F., İşcan, G., Krogerus, S., Yli-Kauhaluoma, J. T., Moreira, V. M. & Tammela, P. S. M., jan 2017, I : Bioorganic & Medicinal Chemistry. 25, 1, s. 132-137 6 s.

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Regioselective Benzylic Oxidation of Aromatic Abietanes: Application to the Semisynthesis of the Naturally Occurring Picealactones A, B and C

Kolsi, L. E., Krogerus, S., Brito, V., Rüffer, T., Lang, H., Yli-Kauhaluoma, J. T., Silvestre, S. & Moreira, V. M., 22 aug 2017, I : ChemistrySelect. 2, 24, s. 7008-7012 5 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2016

Abietane-Type Diterpenoid Amides with Highly Potent and Selective Activity against Leishmania donovani and Trypanosoma cruzi

Pirttimaa, M., Nasereddin, A., Kopelyanskiy, D., Kaiser, M., Yli-Kauhaluoma, J., Oksman-Caldentey, K-M., Brun, R., Jaffe, C. L., Moreira, V. M. & Alakurtti, S., feb 2016, I : Journal of Natural Products. 79, 2, s. 362-368 7 s.

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Antiprotozoal activity of dehydroabietic acid derivatives against Leishmania donovani and Trypanosoma cruzi - SPECIAL ISSUE "NEW TALENT: EUROPE"

Vahermo, M., Krogerus, S., Nasereddin, A., Kaiser, M., Brun, R., Jaffe, C. L., Yli-Kauhaluoma, J. & Moreira, V. M., 2016, I : MedChemComm. 7, 3, s. 457-463 7 s.

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Betulin Derivatives Effectively Suppress Inflammation in Vitro and in Vivo

Laavola, M., Haavikko, R., Hämäläinen, M., Leppänen, T., Nieminen, R., Alakurtti, S., Moreira, V. M., Yli-Kauhaluoma, J. & Moilanen, E., feb 2016, I : Journal of Natural Products. 79, 2, s. 274-280 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Synthesis and Anti-Proliferative Activity of Sulfanyltriazolylnaphthalenols and Sulfanyltriazolylnaphthalene-1,4-diones

Chaaban, I., El Khawass, E. S. M., Abd El Razik, H. A., El Salamouni, N. S., Redondo-Horcajo, M., Barasoain, I., Fernando Diaz, J., Yli-Kauhaluoma, J. & Moreira, V. M., sep 2016, I : Archiv der Pharmazie : Chemistry in life sciences. 349, 9, s. 749-761 13 s.

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2015

New derivatives of dehydroabietic acid target planktonic and biofilm bacteria in Staphylococcus aureus and effectively disrupt bacterial membrane integrity

Manner, S., Vahermo, M., Skogman, M., Krogerus, S., Vuorela, P. M., Yli-Kauhaluoma, J., Fallarero, A. & Moreira, V. M., 21 jul 2015, I : European Journal of Medicinal Chemistry. 102, s. 68-79 12 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development

Härmä, V., Haavikko, R., Virtanen, J., Ahonen, I., Schukov, H-P., Alakurtti, S., Purev, E., Rischer, H., Yli-Kauhaluoma, J., Moreira, V. M., Nees, M. & Oksman-Caldentey, K-M., 12 maj 2015, I : PLoS One. 10, 5, 22 s., 0126111.

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2014

Isolation and purification of ent-pimara-8(14),15-diene from engineered Aspergillus nidulans by accelerated solvent extraction combined with HPLC

Bromann, K., Viljanen, K., Moreira, V. M., Yli-Kauhaluoma, J., Ruohonen, L. & Nakari-Setälä, T., 2014, I : Analytical Methods. 6, 4, s. 1227-1234 8 s.

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Synthesis and biological evaluation of new oxadiazoline-substituted naphthalenyl acetates as anticancer agents

Chaaban, I., El Khawass, E. S. M., El Razik, H. A. A., El Salamouni, N. S., Redondo-Horcajo, M., Barasoain, I., Díaz, J. F., Yli-Kauhaluoma, J. & Moreira, V. M., okt 2014, I : European Journal of Medicinal Chemistry. 87, s. 805-813 9 s.

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2013

(+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro

Fallarero, A., Skogman, M., Kujala, J., Rajaratnam, M., Moreira, V. M., Yli-Kauhaluoma, J. & Vuorela, P., jun 2013, I : International Journal of Molecular Sciences. 14, 6, s. 12054-12072 19 s.

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Drug repositioning: a machine-learning approach through data integration

Napolitano, F., Zhao, Y., Moreira, V. M., Tagliaferri, R., Kere, J., D'Amato, M. & Greco, D., 22 jun 2013, I : Journal of Cheminformatics. 5, Article Number: 30 , 9 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Novel Oleanolic Vinyl Boronates: Synthesis and Antitumor Activity

Moreira, V. M., Salvador, J. A. R., Simões, S., Destro, F. & Gavioli, R., 31 jan 2013, I : European Journal of Medicinal Chemistry. 63, s. 46-56

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2012

Efficient oxidation of oleanolic acid derivatives using magnesium bis(monoperoxyphthalate) hexahydrate (MMPP): A convenient 2-step procedure towards 12-oxo-28-carboxylic acid derivatives.

Salvador, J. A. R., Moreira, V. M., Pinto, R. M. A., Leal, A. S. & Paixão, J. A., 30 jan 2012, I : Beilstein Journal of Organic Chemistry. 8, s. 164-169 6 s.

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2011

Bismuth(III) Triflate-Based Catalytic Direct Opening of Oleanolic Hydroxy-gamma-lactones to Afford 12-Oxo-28-carboxylic Acids

Salvador, J. A. R., Moreira, V. M., Pinto, R. M. A., Leal, A. S. & Le Roux, C., 10 okt 2011, I : Advanced Synthesis & Catalysis. 353, s. 2637-2642

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The reaction of azoles with 17-chloro-16-formylandrosta-5,16-dien-3-yl-acetate: Synthesis and structural elucidation of novel 16-azolylmethylene-17-oxoandrostanes.

Moreira, V. M., Salvador, J. A. R., Matos Beja, A. & Paixão, J. A., 23 feb 2011, I : Steroids. 76, s. 582-587

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2009
2008

1H-and 2H-indazole derivatives of androsta-5,16-dien-3β-ol

Silva, M. R., Moreira, V., Cardoso, C., M. Beja, A. & Salvador, J. A. R., 15 mar 2008, I : Acta Crystallographica. Section C: Crystal Structure Communications. C64, s. o217-o219

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Conformation of 17-Chloro-16-formylandrosta-5,16-dien-3β-yl acetate and 17-chloroandrosta-5,16-dien-3β-yl acetate

Silva, M. R., Moreira, V. M., Cardoso, C., Matos Beja, A. & Salvador, J. A. R., 2008, I : Acta Crystallographica. Section C: Crystal Structure Communications. C64, s. o529-o531

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

Synthesis of novel C17 steroidal carbamates. Studies on CYP17 action, androgen receptor binding and function, and prostate cancer cell growth

Moreira, V. M., Vasaitis, T. S., Guo, Z., Njar, V. C. O. & Salvador, J. A. R., 6 jun 2008, I : Steroids. 73, s. 1217-1227

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review

2007

3-Oxoandrost-4-en-17beta-yl 1H-imidazole-1-carboxylate

Silva, M. R., Matos Beja, A., Moreira, V., Santos, R. C. & Salvador, J. A. R., 9 nov 2007, I : Acta Crystallographica. Section E: Structure Reports Online. E63, s. o4824-

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Synthesis and evaluation of novel 17-indazole androstene derivatives designed as CYP17 inhibitors

Moreira, V., Vasaitis, T. S., Njar, V. C. O. & Salvador, J. A. R., 15 aug 2007, I : Steroids. 72, s. 939-948

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2005

One-pot, high yield synthesis of α-ketols from delta5-steroids

Salvador, J. A. R., Moreira, V., Hanson, J. R. & Carvalho, R. A., 20 dec 2005, I : Steroids. 71, s. 266-272 7 s.

Forskningsoutput: TidskriftsbidragArtikelVetenskapligPeer review